Prenatal diagnosis of placental mesenchymal dysplasia

Placental mesenchymal dysplasia is a rare and benign placental abnormality. It is characterized by placentomegaly with multiple cystic lesions of the villous tree and vascular abnormalities along with increased maternal serum alpha-fetoprotein concentrations. It is an unknown clinical entity and can...

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Detalhes bibliográficos
Autores: Reyna-Villasmil, Eduardo; Torres-Cepeda, Duly; Rondon-Tapia, Martha
Tipo de documento: Artigo
Estado:Published version
Data de publicação:2021
País:Perú
Recursos:SPOG
Repositório:Revista Peruana de Ginecología y Obstetricia
Idioma:Espanhol
Inglês
OAI Identifier:oai:ginecologiayobstetricia.pe:article/2309
Acesso em linha:https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2309
Nível de acesso:Acesso aberto
Palavra-chave:Placental diseases
Ultrasound
Prenatal diagnosis
Enfermedades placentarias
Ultrasonografía
Diagnóstico prenatal
Descrição
Resumo:Placental mesenchymal dysplasia is a rare and benign placental abnormality. It is characterized by placentomegaly with multiple cystic lesions of the villous tree and vascular abnormalities along with increased maternal serum alpha-fetoprotein concentrations. It is an unknown clinical entity and can be confused with gestational trophoblastic disease due to the similar ultrasound findings in both entities; but the management and the perinatal outcome are different. It should be included in the differential diagnosis of ultrasound findings showing a normal-appearing fetus and a placenta with cystic lesions. However, placental mesenchymal dysplasia is associated with complications such as intrauterine growth restriction and intrauterine fetal death. Due to the high number of complications and associated pathologies, it is necessary to increase ultrasound evaluations to reduce fetal morbidity and mortality. A case of prenatal diagnosis of placental mesenchymal dysplasia with normal fetus is presented.