Prenatal diagnosis of placental mesenchymal dysplasia

Placental mesenchymal dysplasia is a rare and benign placental abnormality. It is characterized by placentomegaly with multiple cystic lesions of the villous tree and vascular abnormalities along with increased maternal serum alpha-fetoprotein concentrations. It is an unknown clinical entity and can...

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Bibliographic Details
Authors: Reyna-Villasmil, Eduardo; Torres-Cepeda, Duly; Rondon-Tapia, Martha
Format: Article
Status:Published version
Publication date:2021
Country:Perú
Institution:SPOG
Repository:Revista Peruana de Ginecología y Obstetricia
Language:Spanish
English
OAI Identifier:oai:ginecologiayobstetricia.pe:article/2309
Online Access:https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2309
Access Level:Open access
Keyword:Placental diseases
Ultrasound
Prenatal diagnosis
Enfermedades placentarias
Ultrasonografía
Diagnóstico prenatal
Description
Summary:Placental mesenchymal dysplasia is a rare and benign placental abnormality. It is characterized by placentomegaly with multiple cystic lesions of the villous tree and vascular abnormalities along with increased maternal serum alpha-fetoprotein concentrations. It is an unknown clinical entity and can be confused with gestational trophoblastic disease due to the similar ultrasound findings in both entities; but the management and the perinatal outcome are different. It should be included in the differential diagnosis of ultrasound findings showing a normal-appearing fetus and a placenta with cystic lesions. However, placental mesenchymal dysplasia is associated with complications such as intrauterine growth restriction and intrauterine fetal death. Due to the high number of complications and associated pathologies, it is necessary to increase ultrasound evaluations to reduce fetal morbidity and mortality. A case of prenatal diagnosis of placental mesenchymal dysplasia with normal fetus is presented.