Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine
Nanoparticles have become a powerful tool in oncology not only as carrier of the highly toxic chemotherapeutic drugs but also as imaging contrast agents that provide valuable information about the state of the disease and its progression. The enhanced permeation and retention effect for loaded nanoc...
| Autores: | ; |
|---|---|
| Tipo de documento: | Artículo |
| Fecha de publicación: | 2020 |
| País: | España |
| Institución: | Universidad Complutense de Madrid (UCM) |
| Repositorio: | Docta Complutense |
| Lenguaje: | Inglés |
| OAI Identifier: | oai:docta.ucm.es:20.500.14352/6636 |
| Acceso en línea: | https://hdl.handle.net/20.500.14352/6636 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | nanomedicine mesoporous silica nanoparticles theranostics antitumoral therapy. Materiales 3312 Tecnología de Materiales |
| _version_ | 1878742731425054720 |
|---|---|
| author | Baeza, Alejandro |
| author2 | Vallet Regí, María Dulce Nombre |
| author2_role | author |
| author_browse | Baeza, Alejandro Vallet Regí, María Dulce Nombre |
| author_facet | Baeza, Alejandro Vallet Regí, María Dulce Nombre |
| author_role | author |
| collection | Docta Complutense |
| description | Nanoparticles have become a powerful tool in oncology not only as carrier of the highly toxic chemotherapeutic drugs but also as imaging contrast agents that provide valuable information about the state of the disease and its progression. The enhanced permeation and retention effect for loaded nanocarriers in tumors allow substantial improvement of selectivity and safety of anticancer nanomedicines. Additionally, the possibility to design stimuli-responsive nanocarriers able to release their payload in response to specific stimuli provide an excellent control on the administered dosage. The aim of this review is not to present a comprehensive revision of the different theranostic mesoporous silica nanoparticles (MSN) which have been published in the recent years but just to describe a few selected examples to offer a panoramic view to the reader about the suitability and effectiveness of these nanocarriers in the oncology field. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_fb3f3305f4f1d5e65d2e3d5a4a68c246 |
| institution | Universidad Complutense de Madrid (UCM) |
| instname_str | Universidad Complutense de Madrid (UCM) |
| language | eng |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:docta.ucm.es:20.500.14352/6636 |
| publishDate | 2020 |
| publishDateSort | 2020 |
| publisher | MDPI |
| publisherStr | MDPI |
| reponame_str | Docta Complutense |
| spelling | Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine Baeza, Alejandro Vallet Regí, María Dulce Nombre nanomedicine mesoporous silica nanoparticles theranostics antitumoral therapy. Materiales 3312 Tecnología de Materiales Nanoparticles have become a powerful tool in oncology not only as carrier of the highly toxic chemotherapeutic drugs but also as imaging contrast agents that provide valuable information about the state of the disease and its progression. The enhanced permeation and retention effect for loaded nanocarriers in tumors allow substantial improvement of selectivity and safety of anticancer nanomedicines. Additionally, the possibility to design stimuli-responsive nanocarriers able to release their payload in response to specific stimuli provide an excellent control on the administered dosage. The aim of this review is not to present a comprehensive revision of the different theranostic mesoporous silica nanoparticles (MSN) which have been published in the recent years but just to describe a few selected examples to offer a panoramic view to the reader about the suitability and effectiveness of these nanocarriers in the oncology field. MDPI https://hdl.handle.net/20.500.14352/6636 |
| spellingShingle | Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine Baeza, Alejandro nanomedicine mesoporous silica nanoparticles theranostics antitumoral therapy. Materiales 3312 Tecnología de Materiales |
| title | Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine |
| title_full | Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine |
| title_fullStr | Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine |
| title_full_unstemmed | Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine |
| title_short | Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine |
| title_sort | Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicine |
| topic | nanomedicine mesoporous silica nanoparticles theranostics antitumoral therapy. Materiales 3312 Tecnología de Materiales |
| topic_facet | nanomedicine mesoporous silica nanoparticles theranostics antitumoral therapy. Materiales 3312 Tecnología de Materiales |
| url | https://hdl.handle.net/20.500.14352/6636 |