The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction
Background A higher incidence of childhood trauma (CT) has been reported in first episode of psychosis (FEP). There is, however, a lack of knowledge about the synergetic effect between CT and recent stressful events (RSE). Methods Information on specific types of CT (under 17 years) and RSE (within...
| Autores: | ; ; ; ; ; ; ; |
|---|---|
| Tipo de documento: | Artículo |
| Estado: | Accepted version |
| Fecha de publicación: | 2019 |
| País: | España |
| Institución: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2445/173141 |
| Acceso en línea: | https://hdl.handle.net/2445/173141 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | Traumes psíquics Malalties mentals Infants Psychic trauma Mental illness Children |
| _version_ | 1878742478120550400 |
|---|---|
| author | Ayesa Arriola, Rosa |
| author2 | Setien Suero, Esther Marques-Feixa, Laia Neergaard, Karl Butjosa, A. Vázquez-Bourgon, J. Fañanás Saura, Lourdes Crespo Facorro, Benedicto |
| author2_role | author author author author author author author |
| author_browse | Ayesa Arriola, Rosa Butjosa, A. Crespo Facorro, Benedicto Fañanás Saura, Lourdes Marques-Feixa, Laia Neergaard, Karl Setien Suero, Esther Vázquez-Bourgon, J. |
| author_facet | Ayesa Arriola, Rosa Setien Suero, Esther Marques-Feixa, Laia Neergaard, Karl Butjosa, A. Vázquez-Bourgon, J. Fañanás Saura, Lourdes Crespo Facorro, Benedicto |
| author_role | author |
| collection | Recercat. Dipósit de la Recerca de Catalunya |
| description | Background A higher incidence of childhood trauma (CT) has been reported in first episode of psychosis (FEP). There is, however, a lack of knowledge about the synergetic effect between CT and recent stressful events (RSE). Methods Information on specific types of CT (under 17 years) and RSE (within the past 3 years) was available for 290 FEP patients and 52 healthy controls (HC). Cognitive function at baseline was assessed through a comprehensive neuropsychological test battery. Results While 45.2% of FEP patients and 25% of HC reported at least one CT event, 62.7% of FEP and 21.2% of HC reported an RSE. Meanwhile, 36.2% of FEP patients and 9.6% of HC encountered both childhood and recent stressful events. The patients that just reported CT showed normality in all but the verbal memory cognitive domain; those with additive CT and RSE presented worse general cognitive function, specifically on working memory, processing speed, and executive function. RSE and general cognitive dysfunction were significant determinants of psychosis onset. Conclusions These results support a synergetic influence of trauma and stressful events on brain function and allow a better understanding of mediators for psychotic disorders useful in the design of specific strategies based on stress‐targeted therapies. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_f6a5cb4a2d37f41bd8ee9efb5ca927e0 |
| institution | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| instname_str | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:recercat.cat:2445/173141 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher | John Wiley & Sons |
| publisherStr | John Wiley & Sons |
| reponame_str | Recercat. Dipósit de la Recerca de Catalunya |
| spelling | The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction Ayesa Arriola, Rosa Setien Suero, Esther Marques-Feixa, Laia Neergaard, Karl Butjosa, A. Vázquez-Bourgon, J. Fañanás Saura, Lourdes Crespo Facorro, Benedicto Traumes psíquics Malalties mentals Infants Psychic trauma Mental illness Children Background A higher incidence of childhood trauma (CT) has been reported in first episode of psychosis (FEP). There is, however, a lack of knowledge about the synergetic effect between CT and recent stressful events (RSE). Methods Information on specific types of CT (under 17 years) and RSE (within the past 3 years) was available for 290 FEP patients and 52 healthy controls (HC). Cognitive function at baseline was assessed through a comprehensive neuropsychological test battery. Results While 45.2% of FEP patients and 25% of HC reported at least one CT event, 62.7% of FEP and 21.2% of HC reported an RSE. Meanwhile, 36.2% of FEP patients and 9.6% of HC encountered both childhood and recent stressful events. The patients that just reported CT showed normality in all but the verbal memory cognitive domain; those with additive CT and RSE presented worse general cognitive function, specifically on working memory, processing speed, and executive function. RSE and general cognitive dysfunction were significant determinants of psychosis onset. Conclusions These results support a synergetic influence of trauma and stressful events on brain function and allow a better understanding of mediators for psychotic disorders useful in the design of specific strategies based on stress‐targeted therapies. John Wiley & Sons https://hdl.handle.net/2445/173141 |
| spellingShingle | The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction Ayesa Arriola, Rosa Traumes psíquics Malalties mentals Infants Psychic trauma Mental illness Children |
| status_str | acceptedVersion |
| title | The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction |
| title_full | The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction |
| title_fullStr | The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction |
| title_full_unstemmed | The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction |
| title_short | The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction |
| title_sort | The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction |
| topic | Traumes psíquics Malalties mentals Infants Psychic trauma Mental illness Children |
| topic_facet | Traumes psíquics Malalties mentals Infants Psychic trauma Mental illness Children |
| url | https://hdl.handle.net/2445/173141 |