Standardized comparison of cardiovascular risk factors prevalence in spanish women and men living with HIV and in the general population

People living with HIV (PLWH) have an increased risk of cardiovascular (CV) disease, likely due to a higher prevalence of CV risk factors. We compared the age-standardized prevalence and management of CV risk factors in PLWH to that of the general population in Spain. Blood pressure, lipid, glucose,...

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Bibliographic Details
Authors: Camps-Vilaró, Anna; Pérez-Fernández, Silvia; Subirana Cachinero, Isaac; Teira, Ramón; Estrada, Vicente; Domingo, Pere; Dégano, Irene R.; Marrugat de la Iglesia, Jaume
Format: Article
Status:Published version
Publication date:2021
Country:España
Institution:Universitat Pompeu Fabra
Repository:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/54031
Online Access:http://hdl.handle.net/10230/54031
http://dx.doi.org/10.3390/jpm11111085
Access Level:Open access
Keyword:HIV
Cardiovascular risk factor
General population
People living with HIV
Prevalence
Description
Summary:People living with HIV (PLWH) have an increased risk of cardiovascular (CV) disease, likely due to a higher prevalence of CV risk factors. We compared the age-standardized prevalence and management of CV risk factors in PLWH to that of the general population in Spain. Blood pressure, lipid, glucose, and anthropometric profiles were cross-sectionally compared along with the treatment of hypertension, dyslipidemia, and diabetes in a general population cohort and a PLWH cohort. Prevalence rates were standardized by the direct method by 10-year age groups in European standard populations and stratified by gender. We included 47,593 individuals aged 35 to 74 years, 28,360 from the general population cohort and 19,233 from the PLWH cohort. Compared to the general population, PLWH had a higher concentration of triglycerides (>35 mg/dL in women and >26 mg/dL in men) and a higher prevalence of smoking (>23% and >17%) and diabetes (>9.9% and >8.5%). The prevalence of treated diabetes, hypertension, and dyslipidemia were up to three-fold lower in both women and men living with HIV. There was a significant difference in PLWH compared to the general population in the lipid, glucose, and anthropometric profile. In addition, PLWH were less often treated for diagnosed diabetes, hypertension, and dyslipidemia.