Association between anxiety and severe quality-of-life impairment in postmenopausal women: Analysis of a multicenter Latin American cross-sectional study

Objective: To evaluate associations between anxiety and severe impairment of quality of life (QoL) in Latin American postmenopausal women. Methods: This was a secondary analysis of a multicenter cross-sectional study among postmenopausal women aged 40 to 59 from 11 Latin American countries. We evalu...

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Detalles Bibliográficos
Autores: Núñez Pizarro, Jorge L.; González Luna, Alejandro; Blümel, Juan E.; Barón, Germán; Bencosme, Ascanio; Benítez, Zully; Bravo, Luz M.; Calle, Andrés; Flores, Daniel; Espinoza, María T.; Gómez, Gustavo; Hernández Bueno, José A.; Martino, Mabel; Lima, Selva; Monterrosa, Alvaro; Mostajo, Desiree; Ojeda, Eliana; Onatra, William; Sánchez, Hugo; Tserotas, Konstantinos; Vallejo, María S.; Witis, Silvina; Zúñiga, María C.; Chedraui, Peter; Mezones-Holguín, Edward
Tipo de documento: Artículo
Fecha de publicación:2017
País:Perú
Institución:UPC
Repositorio:UPC-Institucional
Lenguaje:Inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/620969
Acceso en línea:https://doi.org/10.1097/GME.0000000000000813
http://hdl.handle.net/10757/620969
Nivel de acceso:Acceso abierto
Palabra clave:Anxie
Climateric
Latin America
Menopause
Quality of life
Symptoms
Descripción
Sumario:Objective: To evaluate associations between anxiety and severe impairment of quality of life (QoL) in Latin American postmenopausal women. Methods: This was a secondary analysis of a multicenter cross-sectional study among postmenopausal women aged 40 to 59 from 11 Latin American countries. We evaluated anxiety (The Goldberg Depression and Anxiety Scale), and QoL (Menopause Rating Scale [MRS]), and included sociodemographic, clinical, lifestyle, and anthropometric variables in the analysis. Poisson family generalized linear models with robust standard errors were used to estimate prevalence ratios (PRs) and 95% CIs. There were two adjusted models: a statistical model that included variables associated with the outcomes in bivariate analyses, and an epidemiologic model that included potentially confounding variables from literature review. Results: Data from 3,503 women were included; 61.9% had anxiety (Goldberg). Severe QoL impairment (total MRS score >=17) was present in 13.7% of women, as well as severe symptoms (MRS subscales): urogenital (25.5%), psychological (18.5%), and somatic (4.5%). Anxiety was independently associated with severe QoL impairment and severe symptoms in the epidemiological (MRS total score: PR 3.6, 95% CI, 2.6-5.0; somatic: 5.1, 95% CI, 2.6-10.1; psychological: 2.8, 95% CI, 2.2-3.6; and urogenital: 1.4, 95% CI, 1.2-1.6) and the statistical model (MRS total score: PR 3.5, 95% CI, 2.6-4.9; somatic: 5.0, 95% CI, 2.5-9.9; psychological: 2.9, 95% CI, 2.2-3.7; and urogenital: 1.4; 95% CI, 1.2-1.6). Conclusions: In this postmenopausal Latin American sample, anxiety was independently associated with severe QoL impairment. Hence, screening for anxiety in this population is important.