Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection
Integrase strand transfer inhibitors (INSTI) are a main component of the current antiretroviral regimens recommended for treatment of HIV infection. However, little is known about the impact of INSTI on neurocognition and neuroimaging. We developed a prospective observational trial to evaluate the e...
| Autores: | ; ; ; ; ; ; ; ; ; ; ; ; ; ; |
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| Tipo de documento: | Artículo |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Lenguaje: | Inglés |
| OAI Identifier: | oai:ddd.uab.cat:255608 |
| Acceso en línea: | https://ddd.uab.cat/record/255608 https://dx.doi.org/urn:doi:10.1038/s41598-021-90678-6 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | Infectious diseases Cognitive neuroscience Anxiety Depression Central nervous system infections |
| _version_ | 1878742647142612992 |
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| author | Prats, Anna|||0000-0002-3586-4525 |
| author2 | Martínez-Zalacaín, Ignacio|||0000-0002-4036-0284 Mothe, Beatriz|||0000-0001-9975-407X Negredo Puigmal, Eugènia|||0000-0001-5298-1734 Pérez-Álvarez, Núria|||0000-0001-6582-1553 Garolera, Maite Domenech, Sira|||0000-0002-5700-768X Coll, Pep Meulbroek, Michael Chamorro, Anna Fumaz, Carmina R.|||0000-0003-0838-3395 Ferrer, Maria Jose Clotet Sala, Bonaventura|||0000-0003-3232-4598 Soriano-Mas, Carles|||0000-0003-4574-6597 Muñoz-Moreno, José Antonio|||0000-0002-7239-5422 |
| author2_role | author author author author author author author author author author author author author author |
| author_browse | Chamorro, Anna Clotet Sala, Bonaventura|||0000-0003-3232-4598 Coll, Pep Domenech, Sira|||0000-0002-5700-768X Ferrer, Maria Jose Fumaz, Carmina R.|||0000-0003-0838-3395 Garolera, Maite Martínez-Zalacaín, Ignacio|||0000-0002-4036-0284 Meulbroek, Michael Mothe, Beatriz|||0000-0001-9975-407X Muñoz-Moreno, José Antonio|||0000-0002-7239-5422 Negredo Puigmal, Eugènia|||0000-0001-5298-1734 Prats, Anna|||0000-0002-3586-4525 Pérez-Álvarez, Núria|||0000-0001-6582-1553 Soriano-Mas, Carles|||0000-0003-4574-6597 |
| author_facet | Prats, Anna|||0000-0002-3586-4525 Martínez-Zalacaín, Ignacio|||0000-0002-4036-0284 Mothe, Beatriz|||0000-0001-9975-407X Negredo Puigmal, Eugènia|||0000-0001-5298-1734 Pérez-Álvarez, Núria|||0000-0001-6582-1553 Garolera, Maite Domenech, Sira|||0000-0002-5700-768X Coll, Pep Meulbroek, Michael Chamorro, Anna Fumaz, Carmina R.|||0000-0003-0838-3395 Ferrer, Maria Jose Clotet Sala, Bonaventura|||0000-0003-3232-4598 Soriano-Mas, Carles|||0000-0003-4574-6597 Muñoz-Moreno, José Antonio|||0000-0002-7239-5422 |
| author_role | author |
| collection | Dipòsit Digital de Documents de la UAB |
| description | Integrase strand transfer inhibitors (INSTI) are a main component of the current antiretroviral regimens recommended for treatment of HIV infection. However, little is known about the impact of INSTI on neurocognition and neuroimaging. We developed a prospective observational trial to evaluate the effects of INSTI-based antiretroviral therapy on comprehensive brain outcomes (cognitive, functional, and imaging) according to the time since HIV-1 acquisition. We recruited men living with HIV who initiated antiretroviral therapy with INSTI < 3 months since the estimated date of HIV-1 acquisition (n = 12) and. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_f9b232bfbb67f91d93b2e01b6967f892 |
| institution | Universitat Autònoma de Barcelona |
| instname_str | Universitat Autònoma de Barcelona |
| language | eng |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:ddd.uab.cat:255608 |
| publishDate | 2021 |
| publishDateSort | 2021 |
| reponame_str | Dipòsit Digital de Documents de la UAB |
| spelling | Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection Prats, Anna|||0000-0002-3586-4525 Martínez-Zalacaín, Ignacio|||0000-0002-4036-0284 Mothe, Beatriz|||0000-0001-9975-407X Negredo Puigmal, Eugènia|||0000-0001-5298-1734 Pérez-Álvarez, Núria|||0000-0001-6582-1553 Garolera, Maite Domenech, Sira|||0000-0002-5700-768X Coll, Pep Meulbroek, Michael Chamorro, Anna Fumaz, Carmina R.|||0000-0003-0838-3395 Ferrer, Maria Jose Clotet Sala, Bonaventura|||0000-0003-3232-4598 Soriano-Mas, Carles|||0000-0003-4574-6597 Muñoz-Moreno, José Antonio|||0000-0002-7239-5422 Infectious diseases Cognitive neuroscience Anxiety Depression Central nervous system infections Integrase strand transfer inhibitors (INSTI) are a main component of the current antiretroviral regimens recommended for treatment of HIV infection. However, little is known about the impact of INSTI on neurocognition and neuroimaging. We developed a prospective observational trial to evaluate the effects of INSTI-based antiretroviral therapy on comprehensive brain outcomes (cognitive, functional, and imaging) according to the time since HIV-1 acquisition. We recruited men living with HIV who initiated antiretroviral therapy with INSTI < 3 months since the estimated date of HIV-1 acquisition (n = 12) and. https://ddd.uab.cat/record/255608 https://dx.doi.org/urn:doi:10.1038/s41598-021-90678-6 |
| spellingShingle | Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection Prats, Anna|||0000-0002-3586-4525 Infectious diseases Cognitive neuroscience Anxiety Depression Central nervous system infections |
| title | Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection |
| title_full | Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection |
| title_fullStr | Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection |
| title_full_unstemmed | Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection |
| title_short | Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection |
| title_sort | Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection |
| topic | Infectious diseases Cognitive neuroscience Anxiety Depression Central nervous system infections |
| topic_facet | Infectious diseases Cognitive neuroscience Anxiety Depression Central nervous system infections |
| url | https://ddd.uab.cat/record/255608 https://dx.doi.org/urn:doi:10.1038/s41598-021-90678-6 |