Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films

A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical,...

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Authors: Figueiredo, Andrea G. P. R.; Figueiredo, Ana R. P.; Alonso Varona, Ana Isabel; De Matos Fernandes, Susana; Palomares Casado, Teodoro; Rubio Azpeitia, Eva; Barros-Timmons, Ana; Silvestre, Armando J. D.; Neto, Carlos Pascoal; Freire, Carmen S. R.
Format: Article
Publication date:2013
Country:España
Institution:Universidad del País Vasco
Repository:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/11289
Online Access:http://hdl.handle.net/10810/11289
Access Level:Open access
Keyword:cellulose
hydrogels
composites
scaffolds
diffusion
delivery
phema
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author Figueiredo, Andrea G. P. R.
author2 Figueiredo, Ana R. P.
Alonso Varona, Ana Isabel
De Matos Fernandes, Susana
Palomares Casado, Teodoro
Rubio Azpeitia, Eva
Barros-Timmons, Ana
Silvestre, Armando J. D.
Neto, Carlos Pascoal
Freire, Carmen S. R.
author2_role author
author
author
author
author
author
author
author
author
author_browse Alonso Varona, Ana Isabel
Barros-Timmons, Ana
De Matos Fernandes, Susana
Figueiredo, Ana R. P.
Figueiredo, Andrea G. P. R.
Freire, Carmen S. R.
Neto, Carlos Pascoal
Palomares Casado, Teodoro
Rubio Azpeitia, Eva
Silvestre, Armando J. D.
author_facet Figueiredo, Andrea G. P. R.
Figueiredo, Ana R. P.
Alonso Varona, Ana Isabel
De Matos Fernandes, Susana
Palomares Casado, Teodoro
Rubio Azpeitia, Eva
Barros-Timmons, Ana
Silvestre, Armando J. D.
Neto, Carlos Pascoal
Freire, Carmen S. R.
author_role author
collection Addi. Archivo Digital para la Docencia y la Investigación
description A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.
eu_rights_str_mv openAccess
format article
id ES_f83e18b2030e005dfd9ff44b11fe8de7
institution Universidad del País Vasco
instname_str Universidad del País Vasco
network_acronym_str ES
network_name_str España
oai_identifier_str oai:addi.ehu.eus:10810/11289
publishDate 2013
publishDateSort 2013
publisher Hindawi Publishing Corporation
publisherStr Hindawi Publishing Corporation
reponame_str Addi. Archivo Digital para la Docencia y la Investigación
spelling Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films Figueiredo, Andrea G. P. R. Figueiredo, Ana R. P. Alonso Varona, Ana Isabel De Matos Fernandes, Susana Palomares Casado, Teodoro Rubio Azpeitia, Eva Barros-Timmons, Ana Silvestre, Armando J. D. Neto, Carlos Pascoal Freire, Carmen S. R. cellulose hydrogels composites scaffolds diffusion delivery phema A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications. Andrea G. P. R. Figueiredo and Susana C. M. Fernandes thank the Fundacao para a Ciencia e Tecnologia (Portugal) for their Scientific Research Grants (SFRH/BPD/63219/2009 and SFRH/BPD/70119/2010, resp.), cofinancing by POPH/ESF Program. The authors thank CICECO (Pest-C/CTM/LA0011/2013) and FCT for funding within the scope of the "National Program for Scientific reequipment," Rede/1509/RME/2005, REEQ/515/CTM/2005, and University of the Basque Country for financial support (UPV/EHU, Project GIU 10/16). The authors also acknowledge the technical and human support of General Research Services (SGIker) from the UPV/EHU for the SEM analysis. Hindawi Publishing Corporation http://hdl.handle.net/10810/11289
spellingShingle Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
Figueiredo, Andrea G. P. R.
cellulose
hydrogels
composites
scaffolds
diffusion
delivery
phema
title Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title_full Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title_fullStr Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title_full_unstemmed Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title_short Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
title_sort Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films
topic cellulose
hydrogels
composites
scaffolds
diffusion
delivery
phema
topic_facet cellulose
hydrogels
composites
scaffolds
diffusion
delivery
phema
url http://hdl.handle.net/10810/11289