Epidemiological Study of Rickettsial Infections in Patients with Hypertransaminemia in Madrid (Spain)

A retrospective analysis was performed to detect anti-rickettsial antibodies in the serum of patients with hypertransaminemia of unknown etiology, and in that of healthy members of the general population of Madrid (Spain). Among 143 patients 16 (11.2%) were positive for anti-R. conorii IgG antibodie...

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Bibliographic Details
Authors: Lledó García, María Lourdes|||0000-0001-5387-6792; Gegúndez Cámara, María Isabel|||0000-0003-4986-1605; Beltrán Dubón, María; Saz Pérez, José Vicente; González, Rosario
Format: Article
Publication date:2009
Country:España
Institution:Universidad de Cádiz
Repository:e_Buah Biblioteca Digital Universidad de Alcalá
Language:English
OAI Identifier:oai:ebuah.uah.es:10017/61149
Online Access:http://hdl.handle.net/10017/61149
https://dx.doi.org/10.3390/ijerph6102526
Access Level:Open access
Keyword:Rickettsiae
hypertransaminemia
liver dysfunction
prevalence
Spain
Medicina
Medicine
Description
Summary:A retrospective analysis was performed to detect anti-rickettsial antibodies in the serum of patients with hypertransaminemia of unknown etiology, and in that of healthy members of the general population of Madrid (Spain). Among 143 patients 16 (11.2%) were positive for anti-R. conorii IgG antibodies and 7% for R. typhi. PCR analysis was performed in patients with IgM antibodies. Among 143 healthy subjects from the general population, seven (4.9%) were positive for anti-R. conorii IgG antibodies, and 2.8% for R. typhi. These results show that anti-rickettsial antibodies are more commonly detected in patients with hypertransaminemia than in healthy people.