Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
Background: Lichen planus (LP) is a chronic autoimmune disease that affects the oral mucosa as well as the skin, genital mucosa and other sites. Objective: to evaluate the correlation between oral, genital and cutaneous lichen planus, in a sample of LP patients. Material and methods: This descriptiv...
| Authors: | ; ; ; ; ; |
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| Format: | Article |
| Status: | Published version |
| Publication date: | 2019 |
| Country: | España |
| Institution: | Universidad de Barcelona |
| Repository: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/171919 |
| Online Access: | https://hdl.handle.net/2445/171919 |
| Access Level: | Open access |
| Keyword: | Liquen pla Manifestacions orals de les malalties Aparell genital Lichen planus Oral manifestations of general diseases Generative organs |
| _version_ | 1878741888856489985 |
|---|---|
| author | Cassol Spanemberg, Juliana |
| author2 | Blanco Carrión, Andrés Rodríguez de Rivera Campillo, Ma Eugenia Estrugo Devesa, Albert Jané Salas, Enric López López, José, 1958- |
| author2_role | author author author author author |
| author_browse | Blanco Carrión, Andrés Cassol Spanemberg, Juliana Estrugo Devesa, Albert Jané Salas, Enric López López, José, 1958- Rodríguez de Rivera Campillo, Ma Eugenia |
| author_facet | Cassol Spanemberg, Juliana Blanco Carrión, Andrés Rodríguez de Rivera Campillo, Ma Eugenia Estrugo Devesa, Albert Jané Salas, Enric López López, José, 1958- |
| author_role | author |
| collection | Dipòsit Digital de la UB |
| description | Background: Lichen planus (LP) is a chronic autoimmune disease that affects the oral mucosa as well as the skin, genital mucosa and other sites. Objective: to evaluate the correlation between oral, genital and cutaneous lichen planus, in a sample of LP patients. Material and methods: This descriptive study reviewed 274 clinical histories of patients, who all presented histological confirmation of lichen planus verified by a pathologist, attending research centers in Barcelona. Results: A total of 40 LP patients (14.59%) presented genital lesions. Of 131 patients with cutaneous LP (47.8%), the most commonly affected zones were the body's flexor surfaces, representing 60.1% of cases. 24% of patients (n=55) related the start of the lesions with previous stress events. Of the 131 subjects with cutaneous lesions, 19% (n=25) also presented oral lichen planus (OLP). Of the total sample, 53.6% (n=147) of patients presented oral lesions. The systemic diseases most commonly associated with this patient sample were psychological problems such as stress, anxiety and depression (48%), hypertension (27%), gastric problems (12%), and diabetes (9.7%). A family history of lichen planus was found in only 2 cases (0,72%) out of the total of 274. Conclusions: Any patient with OLP should undergo a thorough history and examination to investigate potential extraoral manifestations. The fact that 37 patients with OLP in this patient series were identified with simultaneous involvement at more than one site highlights the need for thorough evaluation and multidisciplinary approaches to this disease. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_ecedd1f6fd28a67efac2e55f47bf5cfd |
| institution | Universidad de Barcelona |
| instname_str | Universidad de Barcelona |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:diposit.ub.edu:2445/171919 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher | Medicina Oral SL |
| publisherStr | Medicina Oral SL |
| reponame_str | Dipòsit Digital de la UB |
| spelling | Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients Cassol Spanemberg, Juliana Blanco Carrión, Andrés Rodríguez de Rivera Campillo, Ma Eugenia Estrugo Devesa, Albert Jané Salas, Enric López López, José, 1958- Liquen pla Manifestacions orals de les malalties Aparell genital Lichen planus Oral manifestations of general diseases Generative organs Background: Lichen planus (LP) is a chronic autoimmune disease that affects the oral mucosa as well as the skin, genital mucosa and other sites. Objective: to evaluate the correlation between oral, genital and cutaneous lichen planus, in a sample of LP patients. Material and methods: This descriptive study reviewed 274 clinical histories of patients, who all presented histological confirmation of lichen planus verified by a pathologist, attending research centers in Barcelona. Results: A total of 40 LP patients (14.59%) presented genital lesions. Of 131 patients with cutaneous LP (47.8%), the most commonly affected zones were the body's flexor surfaces, representing 60.1% of cases. 24% of patients (n=55) related the start of the lesions with previous stress events. Of the 131 subjects with cutaneous lesions, 19% (n=25) also presented oral lichen planus (OLP). Of the total sample, 53.6% (n=147) of patients presented oral lesions. The systemic diseases most commonly associated with this patient sample were psychological problems such as stress, anxiety and depression (48%), hypertension (27%), gastric problems (12%), and diabetes (9.7%). A family history of lichen planus was found in only 2 cases (0,72%) out of the total of 274. Conclusions: Any patient with OLP should undergo a thorough history and examination to investigate potential extraoral manifestations. The fact that 37 patients with OLP in this patient series were identified with simultaneous involvement at more than one site highlights the need for thorough evaluation and multidisciplinary approaches to this disease. Medicina Oral SL https://hdl.handle.net/2445/171919 |
| spellingShingle | Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients Cassol Spanemberg, Juliana Liquen pla Manifestacions orals de les malalties Aparell genital Lichen planus Oral manifestations of general diseases Generative organs |
| status_str | publishedVersion |
| title | Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients |
| title_full | Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients |
| title_fullStr | Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients |
| title_full_unstemmed | Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients |
| title_short | Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients |
| title_sort | Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients |
| topic | Liquen pla Manifestacions orals de les malalties Aparell genital Lichen planus Oral manifestations of general diseases Generative organs |
| topic_facet | Liquen pla Manifestacions orals de les malalties Aparell genital Lichen planus Oral manifestations of general diseases Generative organs |
| url | https://hdl.handle.net/2445/171919 |