Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)
Genetic variation at the melanocortin-1 receptor (MC1R) gene is correlated with melanin color variation in many birds. Feral pigeons (Columba livia) show two major melanin-based colorations: a red coloration due to pheomelanic pigment and a black coloration due to eumelanic pigment. Furthermore, wit...
| Authors: | ; ; ; ; ; ; ; ; ; |
|---|---|
| Format: | Article |
| Status: | Published version |
| Publication date: | 2013 |
| Country: | España |
| Institution: | Universitat Pompeu Fabra |
| Repository: | Repositorio Digital de la UPF |
| OAI Identifier: | oai:repositori.upf.edu:10230/21320 |
| Online Access: | http://hdl.handle.net/10230/21320 http://dx.doi.org/10.1186/1756-0500-6-310 |
| Access Level: | Open access |
| Keyword: | Columba livia Feral pigeon MC1R Pigmentation Color Birds |
| _version_ | 1878741652980367360 |
|---|---|
| author | Derelle, Romain |
| author2 | Kondrashov, Fyodor A., 1979- Arkhipov, Vladimir Y. Corbel, Hélène Frantz, Adrien Gasparini, Julien Jacquin, Lisa Jacob, Gwenaël Thibault, Sophie Baudry, Emmanuelle |
| author2_role | author author author author author author author author author |
| author_browse | Arkhipov, Vladimir Y. Baudry, Emmanuelle Corbel, Hélène Derelle, Romain Frantz, Adrien Gasparini, Julien Jacob, Gwenaël Jacquin, Lisa Kondrashov, Fyodor A., 1979- Thibault, Sophie |
| author_facet | Derelle, Romain Kondrashov, Fyodor A., 1979- Arkhipov, Vladimir Y. Corbel, Hélène Frantz, Adrien Gasparini, Julien Jacquin, Lisa Jacob, Gwenaël Thibault, Sophie Baudry, Emmanuelle |
| author_role | author |
| collection | Repositorio Digital de la UPF |
| description | Genetic variation at the melanocortin-1 receptor (MC1R) gene is correlated with melanin color variation in many birds. Feral pigeons (Columba livia) show two major melanin-based colorations: a red coloration due to pheomelanic pigment and a black coloration due to eumelanic pigment. Furthermore, within each color type, feral pigeons display continuous variation in the amount of melanin pigment present in the feathers, with individuals varying from pure white to a full dark melanic color. Coloration is highly heritable and it has been suggested that it is under natural or sexual selection, or both. Our objective was to investigate whether MC1R allelic variants are associated with plumage color in feral pigeons./n/nWe sequenced 888 bp of the coding sequence of MC1R among pigeons varying both in the type, eumelanin or pheomelanin, and the amount of melanin in their feathers. We detected 10 non-synonymous substitutions and 2 synonymous substitution but none of them were associated with a plumage type. It remains possible that non-synonymous substitutions that influence coloration are present in the short MC1R fragment that we did not sequence but this seems unlikely because we analyzed the entire functionally important region of the gene./nOur results show that color differences among feral pigeons are probably not attributable to amino acid variation at the MC1R locus. Therefore, variation in regulatory regions of MC1R or variation in other genes may be responsible for the color polymorphism of feral pigeons. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_e8fe2b04a5b92e7b8ab3385db89ebf2f |
| institution | Universitat Pompeu Fabra |
| instname_str | Universitat Pompeu Fabra |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:repositori.upf.edu:10230/21320 |
| publishDate | 2013 |
| publishDateSort | 2013 |
| publisher | BioMed Central |
| publisherStr | BioMed Central |
| reponame_str | Repositorio Digital de la UPF |
| spelling | Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R) Derelle, Romain Kondrashov, Fyodor A., 1979- Arkhipov, Vladimir Y. Corbel, Hélène Frantz, Adrien Gasparini, Julien Jacquin, Lisa Jacob, Gwenaël Thibault, Sophie Baudry, Emmanuelle Columba livia Feral pigeon MC1R Pigmentation Color Birds Genetic variation at the melanocortin-1 receptor (MC1R) gene is correlated with melanin color variation in many birds. Feral pigeons (Columba livia) show two major melanin-based colorations: a red coloration due to pheomelanic pigment and a black coloration due to eumelanic pigment. Furthermore, within each color type, feral pigeons display continuous variation in the amount of melanin pigment present in the feathers, with individuals varying from pure white to a full dark melanic color. Coloration is highly heritable and it has been suggested that it is under natural or sexual selection, or both. Our objective was to investigate whether MC1R allelic variants are associated with plumage color in feral pigeons./n/nWe sequenced 888 bp of the coding sequence of MC1R among pigeons varying both in the type, eumelanin or pheomelanin, and the amount of melanin in their feathers. We detected 10 non-synonymous substitutions and 2 synonymous substitution but none of them were associated with a plumage type. It remains possible that non-synonymous substitutions that influence coloration are present in the short MC1R fragment that we did not sequence but this seems unlikely because we analyzed the entire functionally important region of the gene./nOur results show that color differences among feral pigeons are probably not attributable to amino acid variation at the MC1R locus. Therefore, variation in regulatory regions of MC1R or variation in other genes may be responsible for the color polymorphism of feral pigeons. Romain Derelle was supported by grant from Plan Nacional 004302 BFU2012-31329. Fyodor A Kondrashov was supported by grants HHMI (Howard Hughes Medical Institute) 003803 and EMBO 003691 EUI-EURYIP-2011-4320 BioMed Central http://hdl.handle.net/10230/21320 http://dx.doi.org/10.1186/1756-0500-6-310 |
| spellingShingle | Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R) Derelle, Romain Columba livia Feral pigeon MC1R Pigmentation Color Birds |
| status_str | publishedVersion |
| title | Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R) |
| title_full | Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R) |
| title_fullStr | Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R) |
| title_full_unstemmed | Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R) |
| title_short | Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R) |
| title_sort | Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R) |
| topic | Columba livia Feral pigeon MC1R Pigmentation Color Birds |
| topic_facet | Columba livia Feral pigeon MC1R Pigmentation Color Birds |
| url | http://hdl.handle.net/10230/21320 http://dx.doi.org/10.1186/1756-0500-6-310 |