The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development
Polycomb Group regulation in Arabidopsis (Arabidopsis thaliana) is required to maintain cell differentiation and allow developmental phase transitions. This is achieved by the activity of three PcG repressive complex 2s (PRC2s) and the participation of a yet poorly defined PRC1. Previous results sho...
| Autores: | ; ; ; ; ; |
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| Tipo de documento: | Artículo |
| Estado: | Submitted version |
| Fecha de publicación: | 2017 |
| País: | España |
| Institución: | Universidad de Sevilla (US) |
| Repositorio: | idUS. Depósito de Investigación de la Universidad de Sevilla |
| OAI Identifier: | oai:idus.us.es:11441/111108 |
| Acceso en línea: | https://hdl.handle.net/11441/111108 https://doi.org/10.1104/pp.16.01259 |
| Nivel de acceso: | Acceso abierto |
| _version_ | 1878741138875088896 |
|---|---|
| author | Merini, Wiam |
| author2 | Romero Campero, Francisco José Gómez Zambrano, Ángeles Zhou, Yue Turck, Franziska Calonje, Myriam |
| author2_role | author author author author author |
| author_browse | Calonje, Myriam Gómez Zambrano, Ángeles Merini, Wiam Romero Campero, Francisco José Turck, Franziska Zhou, Yue |
| author_facet | Merini, Wiam Romero Campero, Francisco José Gómez Zambrano, Ángeles Zhou, Yue Turck, Franziska Calonje, Myriam |
| author_role | author |
| collection | idUS. Depósito de Investigación de la Universidad de Sevilla |
| description | Polycomb Group regulation in Arabidopsis (Arabidopsis thaliana) is required to maintain cell differentiation and allow developmental phase transitions. This is achieved by the activity of three PcG repressive complex 2s (PRC2s) and the participation of a yet poorly defined PRC1. Previous results showed that apparent PRC1 components perform discrete roles during plant development, suggesting the existence of PRC1 variants; however, it is not clear in how many processes these components participate. We show that AtBMI1 proteins are required to promote all developmental phase transitions and to control cell proliferation during organ growth and development, expanding their proposed range of action. While AtBMI1 function during germination is closely linked to B3 domain transcription factors VAL1/2 possibly in combination with GT-box binding factors, other AtBMI1 regulatory networks require participation of different factor combinations. Conversely, EMF1 and LHP1 bind many H3K27me3 positive genes up-regulated in atbmi1a/b/c mutants; however, loss of their function affects expression of a different subset, suggesting that even if EMF1, LHP1, and AtBMI1 exist in a common PRC1 variant, their role in repression depends on the functional context. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_dfd55e72551a75ca5a37e799fdd87aec |
| institution | Universidad de Sevilla (US) |
| instname_str | Universidad de Sevilla (US) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:idus.us.es:11441/111108 |
| publishDate | 2017 |
| publishDateSort | 2017 |
| publisher | American Society of Plant Biologists |
| publisherStr | American Society of Plant Biologists |
| reponame_str | idUS. Depósito de Investigación de la Universidad de Sevilla |
| spelling | The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development Merini, Wiam Romero Campero, Francisco José Gómez Zambrano, Ángeles Zhou, Yue Turck, Franziska Calonje, Myriam Polycomb Group regulation in Arabidopsis (Arabidopsis thaliana) is required to maintain cell differentiation and allow developmental phase transitions. This is achieved by the activity of three PcG repressive complex 2s (PRC2s) and the participation of a yet poorly defined PRC1. Previous results showed that apparent PRC1 components perform discrete roles during plant development, suggesting the existence of PRC1 variants; however, it is not clear in how many processes these components participate. We show that AtBMI1 proteins are required to promote all developmental phase transitions and to control cell proliferation during organ growth and development, expanding their proposed range of action. While AtBMI1 function during germination is closely linked to B3 domain transcription factors VAL1/2 possibly in combination with GT-box binding factors, other AtBMI1 regulatory networks require participation of different factor combinations. Conversely, EMF1 and LHP1 bind many H3K27me3 positive genes up-regulated in atbmi1a/b/c mutants; however, loss of their function affects expression of a different subset, suggesting that even if EMF1, LHP1, and AtBMI1 exist in a common PRC1 variant, their role in repression depends on the functional context. Ministerio de Economía y Competitividad BIO2013-44078-P American Society of Plant Biologists https://hdl.handle.net/11441/111108 https://doi.org/10.1104/pp.16.01259 |
| spellingShingle | The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development Merini, Wiam |
| status_str | submittedVersion |
| title | The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development |
| title_full | The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development |
| title_fullStr | The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development |
| title_full_unstemmed | The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development |
| title_short | The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development |
| title_sort | The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development |
| url | https://hdl.handle.net/11441/111108 https://doi.org/10.1104/pp.16.01259 |