Genetic inbreeding depression load for fertility traits in Pura Raza Española mares
Fertility is a key factor in the economic success of horse farms. However, it has received little attention due to the difficulty of measuring fertility objectively. Since its studbook creation (1912), the Pura Raza Española (PRE) breed has been a closed population and become high in-bred resulting...
| Authors: | ; ; ; ; ; |
|---|---|
| Format: | Article |
| Status: | Published version |
| Publication date: | 2021 |
| Country: | España |
| Institution: | Universidad de Sevilla (US) |
| Repository: | idUS. Depósito de Investigación de la Universidad de Sevilla |
| OAI Identifier: | oai:idus.us.es:11441/156569 |
| Online Access: | https://hdl.handle.net/11441/156569 https://doi.org/10.1093/jas/skab316 |
| Access Level: | Open access |
| Keyword: | fertility genetic parameters horses inbreeding depression inbreeding load heterogeneity reproductive efficiency |
| _version_ | 1878740872335458304 |
|---|---|
| author | Perdomo González, Davinia Isabel |
| author2 | Molina, Antonio Sánchez Guerrero, María José Bartolomé Medina, Ester Varona, L. Valera Córdoba, María Mercedes |
| author2_role | author author author author author |
| author_browse | Bartolomé Medina, Ester Molina, Antonio Perdomo González, Davinia Isabel Sánchez Guerrero, María José Valera Córdoba, María Mercedes Varona, L. |
| author_facet | Perdomo González, Davinia Isabel Molina, Antonio Sánchez Guerrero, María José Bartolomé Medina, Ester Varona, L. Valera Córdoba, María Mercedes |
| author_role | author |
| collection | idUS. Depósito de Investigación de la Universidad de Sevilla |
| description | Fertility is a key factor in the economic success of horse farms. However, it has received little attention due to the difficulty of measuring fertility objectively. Since its studbook creation (1912), the Pura Raza Española (PRE) breed has been a closed population and become high in-bred resulting in inbreeding depression (poor phenotypic values). Nevertheless, heterogeneous effects of inbreeding depression have been detected among founders and nonfounders. The aims of this study were (1) to analyze the genetic parameters for reproductive traits in mares of the PRE horse breed and (2) to estimate, for the first time, the inbreeding depression load associated with common ancestors of the breed. A total of 22,799 mares were analyzed. Heritability estimates ranged from 0.05 (interval between first and second foaling) to 0.16 (age at first foaling), whereas inbreeding depression load ratios ranged from 0.06 (parturition efficiency at 6th foaling) to 0.17 (age at first foaling), for a partial inbreeding coefficient of 10%. Although heritability is related to the variability expressed in the population, inbreeding depression load ratios measure the potential variability, whether expressed in the population or not. Most correlations between additive and inbreeding depression load genetic values were significant (P < 0.001) and of low to moderate magnitude. Our results confirm that individual inbreeding depression loads allow us to select horses that have a genetic value resistant to the deleterious effects of inbreeding. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_dae23a7b65ebe98202ec7c9c5186f00a |
| institution | Universidad de Sevilla (US) |
| instname_str | Universidad de Sevilla (US) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:idus.us.es:11441/156569 |
| publishDate | 2021 |
| publishDateSort | 2021 |
| publisher | Oxford University Press |
| publisherStr | Oxford University Press |
| reponame_str | idUS. Depósito de Investigación de la Universidad de Sevilla |
| spelling | Genetic inbreeding depression load for fertility traits in Pura Raza Española mares Perdomo González, Davinia Isabel Molina, Antonio Sánchez Guerrero, María José Bartolomé Medina, Ester Varona, L. Valera Córdoba, María Mercedes fertility genetic parameters horses inbreeding depression inbreeding load heterogeneity reproductive efficiency Fertility is a key factor in the economic success of horse farms. However, it has received little attention due to the difficulty of measuring fertility objectively. Since its studbook creation (1912), the Pura Raza Española (PRE) breed has been a closed population and become high in-bred resulting in inbreeding depression (poor phenotypic values). Nevertheless, heterogeneous effects of inbreeding depression have been detected among founders and nonfounders. The aims of this study were (1) to analyze the genetic parameters for reproductive traits in mares of the PRE horse breed and (2) to estimate, for the first time, the inbreeding depression load associated with common ancestors of the breed. A total of 22,799 mares were analyzed. Heritability estimates ranged from 0.05 (interval between first and second foaling) to 0.16 (age at first foaling), whereas inbreeding depression load ratios ranged from 0.06 (parturition efficiency at 6th foaling) to 0.17 (age at first foaling), for a partial inbreeding coefficient of 10%. Although heritability is related to the variability expressed in the population, inbreeding depression load ratios measure the potential variability, whether expressed in the population or not. Most correlations between additive and inbreeding depression load genetic values were significant (P < 0.001) and of low to moderate magnitude. Our results confirm that individual inbreeding depression loads allow us to select horses that have a genetic value resistant to the deleterious effects of inbreeding. Oxford University Press https://hdl.handle.net/11441/156569 https://doi.org/10.1093/jas/skab316 |
| spellingShingle | Genetic inbreeding depression load for fertility traits in Pura Raza Española mares Perdomo González, Davinia Isabel fertility genetic parameters horses inbreeding depression inbreeding load heterogeneity reproductive efficiency |
| status_str | publishedVersion |
| title | Genetic inbreeding depression load for fertility traits in Pura Raza Española mares |
| title_full | Genetic inbreeding depression load for fertility traits in Pura Raza Española mares |
| title_fullStr | Genetic inbreeding depression load for fertility traits in Pura Raza Española mares |
| title_full_unstemmed | Genetic inbreeding depression load for fertility traits in Pura Raza Española mares |
| title_short | Genetic inbreeding depression load for fertility traits in Pura Raza Española mares |
| title_sort | Genetic inbreeding depression load for fertility traits in Pura Raza Española mares |
| topic | fertility genetic parameters horses inbreeding depression inbreeding load heterogeneity reproductive efficiency |
| topic_facet | fertility genetic parameters horses inbreeding depression inbreeding load heterogeneity reproductive efficiency |
| url | https://hdl.handle.net/11441/156569 https://doi.org/10.1093/jas/skab316 |