Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach
On the basis of the discussion of the current state of research on relevant topics of non-muscle-invasive bladder cancer (NMIBC) among a group of experts of the Spanish Oncology Gen-itourinary (SOGUG) Working Group, recommendations were proposed to overcome the challenges posed by the management of...
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| Format: | Article |
| Publication date: | 2021 |
| Country: | España |
| Institution: | Universitat Autònoma de Barcelona |
| Repository: | Dipòsit Digital de Documents de la UAB |
| Language: | English |
| OAI Identifier: | oai:ddd.uab.cat:270257 |
| Online Access: | https://ddd.uab.cat/record/270257 https://dx.doi.org/urn:doi:10.3390/cancers13194762 |
| Access Level: | Open access |
| Keyword: | Non-muscle-invasive bladder cancer Microhematuria Transurethral resection Histological variants Molecular subtypes Immunotherapy |
| _version_ | 1878740812223741952 |
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| author | Rubio-Briones, José |
| author2 | Algaba, Ferran|||0000-0002-0071-4164 Gallardo Díaz, Enrique|||0000-0002-1375-3488 Marcos-Rodríguez, José Antonio Climent, Miguel Ángel|||0000-0001-7523-0212 Gomez-Caamaño, Antonio|||0000-0002-9773-4590 Garcia Vicente, Ana M. Maroto Rey, Pablo|||0000-0002-0030-0412 Rodríguez Antolín, Alfredo Sanz, Julián Vera González, Maria Almudena González-del-Alba, Aránzazu|||0000-0001-6570-009X Conde Moreno, Antonio José|||0000-0003-1024-0924 González-Haba, Eva González-Peramato, Pilar Linares Espinós, Estefania López-Beltran, Antonio Pelechano, Paula Garrido, Marga Gironés Sarrió, Regina Zapatero, Almudena|||0000-0003-2930-2312 Arranz Alija, Jose Ángel |
| author2_role | author author author author author author author author author author author author author author author author author author author author author |
| author_browse | Algaba, Ferran|||0000-0002-0071-4164 Arranz Alija, Jose Ángel Climent, Miguel Ángel|||0000-0001-7523-0212 Conde Moreno, Antonio José|||0000-0003-1024-0924 Gallardo Díaz, Enrique|||0000-0002-1375-3488 Garcia Vicente, Ana M. Garrido, Marga Gironés Sarrió, Regina Gomez-Caamaño, Antonio|||0000-0002-9773-4590 González-Haba, Eva González-Peramato, Pilar González-del-Alba, Aránzazu|||0000-0001-6570-009X Linares Espinós, Estefania López-Beltran, Antonio Marcos-Rodríguez, José Antonio Maroto Rey, Pablo|||0000-0002-0030-0412 Pelechano, Paula Rodríguez Antolín, Alfredo Rubio-Briones, José Sanz, Julián Vera González, Maria Almudena Zapatero, Almudena|||0000-0003-2930-2312 |
| author_facet | Rubio-Briones, José Algaba, Ferran|||0000-0002-0071-4164 Gallardo Díaz, Enrique|||0000-0002-1375-3488 Marcos-Rodríguez, José Antonio Climent, Miguel Ángel|||0000-0001-7523-0212 Gomez-Caamaño, Antonio|||0000-0002-9773-4590 Garcia Vicente, Ana M. Maroto Rey, Pablo|||0000-0002-0030-0412 Rodríguez Antolín, Alfredo Sanz, Julián Vera González, Maria Almudena González-del-Alba, Aránzazu|||0000-0001-6570-009X Conde Moreno, Antonio José|||0000-0003-1024-0924 González-Haba, Eva González-Peramato, Pilar Linares Espinós, Estefania López-Beltran, Antonio Pelechano, Paula Garrido, Marga Gironés Sarrió, Regina Zapatero, Almudena|||0000-0003-2930-2312 Arranz Alija, Jose Ángel |
| author_role | author |
| collection | Dipòsit Digital de Documents de la UAB |
| description | On the basis of the discussion of the current state of research on relevant topics of non-muscle-invasive bladder cancer (NMIBC) among a group of experts of the Spanish Oncology Gen-itourinary (SOGUG) Working Group, recommendations were proposed to overcome the challenges posed by the management of NMIBC in clinical practice. A unified definition of the term 'microhe-maturia' and the profile of the patient at risk are needed. Establishing a 'hematuria clinic' would contribute to a centralized and more efficient evaluation of patients with this clinical sign. Second or repeated transurethral resection (re-TUR) needs to be defined, including the time window after the first procedure within which re-TUR should be performed. Complete tumor resection is man-datory when feasible, with specification of the presence or absence of muscle. Budding should be used as a classification system, and stratification of T1 tumors especially in extensive and deep tu-mors, is advisable. The percentage of the high-grade component should always be reported, and, in multiple tumors, grades should be reported separately. Luminal and basal subtypes can be identi-fied because of possibly different clinical outcomes. Molecular subtypes and immunotherapy are incorporated in the management of muscle-invasive bladder cancer but data on NMIBC are still preliminary. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_d9d22ea00a82da308965fc039d908918 |
| institution | Universitat Autònoma de Barcelona |
| instname_str | Universitat Autònoma de Barcelona |
| language | eng |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:ddd.uab.cat:270257 |
| publishDate | 2021 |
| publishDateSort | 2021 |
| reponame_str | Dipòsit Digital de Documents de la UAB |
| spelling | Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach Practical recommendations from the spanish oncology genitourinary (sogug) working group Rubio-Briones, José Algaba, Ferran|||0000-0002-0071-4164 Gallardo Díaz, Enrique|||0000-0002-1375-3488 Marcos-Rodríguez, José Antonio Climent, Miguel Ángel|||0000-0001-7523-0212 Gomez-Caamaño, Antonio|||0000-0002-9773-4590 Garcia Vicente, Ana M. Maroto Rey, Pablo|||0000-0002-0030-0412 Rodríguez Antolín, Alfredo Sanz, Julián Vera González, Maria Almudena González-del-Alba, Aránzazu|||0000-0001-6570-009X Conde Moreno, Antonio José|||0000-0003-1024-0924 González-Haba, Eva González-Peramato, Pilar Linares Espinós, Estefania López-Beltran, Antonio Pelechano, Paula Garrido, Marga Gironés Sarrió, Regina Zapatero, Almudena|||0000-0003-2930-2312 Arranz Alija, Jose Ángel Non-muscle-invasive bladder cancer Microhematuria Transurethral resection Histological variants Molecular subtypes Immunotherapy On the basis of the discussion of the current state of research on relevant topics of non-muscle-invasive bladder cancer (NMIBC) among a group of experts of the Spanish Oncology Gen-itourinary (SOGUG) Working Group, recommendations were proposed to overcome the challenges posed by the management of NMIBC in clinical practice. A unified definition of the term 'microhe-maturia' and the profile of the patient at risk are needed. Establishing a 'hematuria clinic' would contribute to a centralized and more efficient evaluation of patients with this clinical sign. Second or repeated transurethral resection (re-TUR) needs to be defined, including the time window after the first procedure within which re-TUR should be performed. Complete tumor resection is man-datory when feasible, with specification of the presence or absence of muscle. Budding should be used as a classification system, and stratification of T1 tumors especially in extensive and deep tu-mors, is advisable. The percentage of the high-grade component should always be reported, and, in multiple tumors, grades should be reported separately. Luminal and basal subtypes can be identi-fied because of possibly different clinical outcomes. Molecular subtypes and immunotherapy are incorporated in the management of muscle-invasive bladder cancer but data on NMIBC are still preliminary. https://ddd.uab.cat/record/270257 https://dx.doi.org/urn:doi:10.3390/cancers13194762 |
| spellingShingle | Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach Rubio-Briones, José Non-muscle-invasive bladder cancer Microhematuria Transurethral resection Histological variants Molecular subtypes Immunotherapy |
| title | Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach |
| title_full | Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach |
| title_fullStr | Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach |
| title_full_unstemmed | Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach |
| title_short | Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach |
| title_sort | Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach |
| topic | Non-muscle-invasive bladder cancer Microhematuria Transurethral resection Histological variants Molecular subtypes Immunotherapy |
| topic_facet | Non-muscle-invasive bladder cancer Microhematuria Transurethral resection Histological variants Molecular subtypes Immunotherapy |
| url | https://ddd.uab.cat/record/270257 https://dx.doi.org/urn:doi:10.3390/cancers13194762 |