Telling true from false: cannabis users show increased susceptibility to false memories
Previous studies on the neurocognitive impact of cannabis use have found working and declarative memory deficits that tend to normalize with abstinence. An unexplored aspect of cognitive function in chronic cannabis users is the ability to distinguish between veridical and illusory memories, a cruci...
| Authors: | ; ; ; ; ; ; |
|---|---|
| Format: | Article |
| Status: | Published version |
| Publication date: | 2015 |
| Country: | España |
| Institution: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repository: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2445/125342 |
| Online Access: | https://hdl.handle.net/2445/125342 |
| Access Level: | Open access |
| Keyword: | Cànnabis Neurociència cognitiva Trastorns de la memòria Cannabis Cognitive neuroscience Memory disorders |
| _version_ | 1878740481936982016 |
|---|---|
| author | Riba, Jordi |
| author2 | Valle, Marta Sampedro, Frederic Rodriguez Pujadas, Aina Martínez Horta, Saúl Kulisevsky, Jaime Rodríguez Fornells, Antoni |
| author2_role | author author author author author author |
| author_browse | Kulisevsky, Jaime Martínez Horta, Saúl Riba, Jordi Rodriguez Pujadas, Aina Rodríguez Fornells, Antoni Sampedro, Frederic Valle, Marta |
| author_facet | Riba, Jordi Valle, Marta Sampedro, Frederic Rodriguez Pujadas, Aina Martínez Horta, Saúl Kulisevsky, Jaime Rodríguez Fornells, Antoni |
| author_role | author |
| collection | Recercat. Dipósit de la Recerca de Catalunya |
| description | Previous studies on the neurocognitive impact of cannabis use have found working and declarative memory deficits that tend to normalize with abstinence. An unexplored aspect of cognitive function in chronic cannabis users is the ability to distinguish between veridical and illusory memories, a crucial aspect of reality monitoring that relies on adequate memory function and cognitive control. Using functional magnetic resonance imaging, we show that abstinent cannabis users have an increased susceptibility to false memories, failing to identify lure stimuli as events that never occurred. In addition to impaired performance, cannabis users display reduced activation in areas associated with memory processing within the lateral and medial temporal lobe (MTL), and in parietal and frontal brain regions involved in attention and performance monitoring. Furthermore, cannabis consumption was inversely correlated with MTL activity, suggesting that the drug is especially detrimental to the episodic aspects of memory. These findings indicate that cannabis users have an increased susceptibility to memory distortions even when abstinent and drug-free, suggesting a long-lasting compromise of memory and cognitive control mechanisms involved in reality monitoring. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_d3d7bfc009446e2ed34ffd8984bd2c8a |
| institution | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| instname_str | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:recercat.cat:2445/125342 |
| publishDate | 2015 |
| publishDateSort | 2015 |
| publisher | Nature Publishing Group |
| publisherStr | Nature Publishing Group |
| reponame_str | Recercat. Dipósit de la Recerca de Catalunya |
| spelling | Telling true from false: cannabis users show increased susceptibility to false memories Riba, Jordi Valle, Marta Sampedro, Frederic Rodriguez Pujadas, Aina Martínez Horta, Saúl Kulisevsky, Jaime Rodríguez Fornells, Antoni Cànnabis Neurociència cognitiva Trastorns de la memòria Cannabis Cognitive neuroscience Memory disorders Previous studies on the neurocognitive impact of cannabis use have found working and declarative memory deficits that tend to normalize with abstinence. An unexplored aspect of cognitive function in chronic cannabis users is the ability to distinguish between veridical and illusory memories, a crucial aspect of reality monitoring that relies on adequate memory function and cognitive control. Using functional magnetic resonance imaging, we show that abstinent cannabis users have an increased susceptibility to false memories, failing to identify lure stimuli as events that never occurred. In addition to impaired performance, cannabis users display reduced activation in areas associated with memory processing within the lateral and medial temporal lobe (MTL), and in parietal and frontal brain regions involved in attention and performance monitoring. Furthermore, cannabis consumption was inversely correlated with MTL activity, suggesting that the drug is especially detrimental to the episodic aspects of memory. These findings indicate that cannabis users have an increased susceptibility to memory distortions even when abstinent and drug-free, suggesting a long-lasting compromise of memory and cognitive control mechanisms involved in reality monitoring. Nature Publishing Group https://hdl.handle.net/2445/125342 |
| spellingShingle | Telling true from false: cannabis users show increased susceptibility to false memories Riba, Jordi Cànnabis Neurociència cognitiva Trastorns de la memòria Cannabis Cognitive neuroscience Memory disorders |
| status_str | publishedVersion |
| title | Telling true from false: cannabis users show increased susceptibility to false memories |
| title_full | Telling true from false: cannabis users show increased susceptibility to false memories |
| title_fullStr | Telling true from false: cannabis users show increased susceptibility to false memories |
| title_full_unstemmed | Telling true from false: cannabis users show increased susceptibility to false memories |
| title_short | Telling true from false: cannabis users show increased susceptibility to false memories |
| title_sort | Telling true from false: cannabis users show increased susceptibility to false memories |
| topic | Cànnabis Neurociència cognitiva Trastorns de la memòria Cannabis Cognitive neuroscience Memory disorders |
| topic_facet | Cànnabis Neurociència cognitiva Trastorns de la memòria Cannabis Cognitive neuroscience Memory disorders |
| url | https://hdl.handle.net/2445/125342 |