Accuracy of standard bipolar amplitude voltage thresholds to identify late potential channels in ventricular tachycardia ablation

Background: Ventricular tachycardia (VT) is caused by the presence of a slow conduction channel (CC) of border zone (BZ) tissue inside the scar-core tissue. Electroanatomic mapping can depict this tissue by voltage mapping. Areas of slow conduction can be detected as late potentials (LPs) and their...

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Autores: Roca Luque, Ivo; Zaraket, Fatima; Garre Anguera de Sojo, Paz; Sánchez Somonte, Paula; Quinto, Levio; Borràs, Roger; Guasch i Casany, Eduard; Arbelo, Elena; Tolosana, José M. (José María); Brugada Terradellas, Josep, 1958-; Mont Girbau, Lluís
Tipo de documento: Artículo
Estado:Published version
Fecha de publicación:2022
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/214271
Acceso en línea:https://hdl.handle.net/2445/214271
Nivel de acceso:Acceso abierto
Palabra clave:Taquicàrdia
Ventricles cardíacs
Cicatrius
Malalties del cor
Tachycardia
Ventricle of heart
Scars
Heart diseases
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author Roca Luque, Ivo
author2 Zaraket, Fatima
Garre Anguera de Sojo, Paz
Sánchez Somonte, Paula
Quinto, Levio
Borràs, Roger
Guasch i Casany, Eduard
Arbelo, Elena
Tolosana, José M. (José María)
Brugada Terradellas, Josep, 1958-
Mont Girbau, Lluís
author2_role author
author
author
author
author
author
author
author
author
author
author_browse Arbelo, Elena
Borràs, Roger
Brugada Terradellas, Josep, 1958-
Garre Anguera de Sojo, Paz
Guasch i Casany, Eduard
Mont Girbau, Lluís
Quinto, Levio
Roca Luque, Ivo
Sánchez Somonte, Paula
Tolosana, José M. (José María)
Zaraket, Fatima
author_facet Roca Luque, Ivo
Zaraket, Fatima
Garre Anguera de Sojo, Paz
Sánchez Somonte, Paula
Quinto, Levio
Borràs, Roger
Guasch i Casany, Eduard
Arbelo, Elena
Tolosana, José M. (José María)
Brugada Terradellas, Josep, 1958-
Mont Girbau, Lluís
author_role author
collection Dipòsit Digital de la UB
description Background: Ventricular tachycardia (VT) is caused by the presence of a slow conduction channel (CC) of border zone (BZ) tissue inside the scar-core tissue. Electroanatomic mapping can depict this tissue by voltage mapping. Areas of slow conduction can be detected as late potentials (LPs) and their abolition is the most accepted ablation endpoint. In the current guidelines, bipolar voltage thresholds for BZ and core scar are 1.5 and 0.5 mV respectively. The performance of these values is controversial. The aim of the study is to analyze the diagnostic yield of current amplitude thresholds in voltage map to define VT substrate in terms of CCs of LPs. Predictors of usefulness of current thresholds will be analyzed. Methods: All patients with structural heart disease who underwent VT ablation in Hospital Clinic in 2016-2017 were included. Maps with delineation of CCs based on LPs were created with contact force sensor catheter. Thresholds were adjusted for every patient based on CCs. Diagnostic yield and predictors of performance of conventional thresholds were analyzed. Results: During study period, 57 consecutive patients were included (age: 60.4 ± 8.5; 50.2% ischemic cardiomyopathy, LVEF 39.8 ± 13.5%). Cutoff voltages that better identified the scar and BZ according to the LP channels were 0.32 (0.02-2 mV) and 1.84 (0.3-6 mV) respectively. Current voltage thresholds identified correctly core and BZ in 87.7% and 42.1% of the patients respectively. Accuracy was worse in non-ischemic cardiomyopathy (NICM) especially for BZ (28.6% vs 55.2%, p = 0.042). Conclusions: Accuracy of standard voltage thresholds for scar and BZ is poor in terms of LPs detection. Diagnostic yield is worse in NICM patients specially for border zone.
eu_rights_str_mv openAccess
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institution Universidad de Barcelona
instname_str Universidad de Barcelona
network_acronym_str ES
network_name_str España
oai_identifier_str oai:diposit.ub.edu:2445/214271
publishDate 2022
publishDateSort 2022
publisher Springer Verlag
publisherStr Springer Verlag
reponame_str Dipòsit Digital de la UB
spelling Accuracy of standard bipolar amplitude voltage thresholds to identify late potential channels in ventricular tachycardia ablation Roca Luque, Ivo Zaraket, Fatima Garre Anguera de Sojo, Paz Sánchez Somonte, Paula Quinto, Levio Borràs, Roger Guasch i Casany, Eduard Arbelo, Elena Tolosana, José M. (José María) Brugada Terradellas, Josep, 1958- Mont Girbau, Lluís Taquicàrdia Ventricles cardíacs Cicatrius Malalties del cor Tachycardia Ventricle of heart Scars Heart diseases Background: Ventricular tachycardia (VT) is caused by the presence of a slow conduction channel (CC) of border zone (BZ) tissue inside the scar-core tissue. Electroanatomic mapping can depict this tissue by voltage mapping. Areas of slow conduction can be detected as late potentials (LPs) and their abolition is the most accepted ablation endpoint. In the current guidelines, bipolar voltage thresholds for BZ and core scar are 1.5 and 0.5 mV respectively. The performance of these values is controversial. The aim of the study is to analyze the diagnostic yield of current amplitude thresholds in voltage map to define VT substrate in terms of CCs of LPs. Predictors of usefulness of current thresholds will be analyzed. Methods: All patients with structural heart disease who underwent VT ablation in Hospital Clinic in 2016-2017 were included. Maps with delineation of CCs based on LPs were created with contact force sensor catheter. Thresholds were adjusted for every patient based on CCs. Diagnostic yield and predictors of performance of conventional thresholds were analyzed. Results: During study period, 57 consecutive patients were included (age: 60.4 ± 8.5; 50.2% ischemic cardiomyopathy, LVEF 39.8 ± 13.5%). Cutoff voltages that better identified the scar and BZ according to the LP channels were 0.32 (0.02-2 mV) and 1.84 (0.3-6 mV) respectively. Current voltage thresholds identified correctly core and BZ in 87.7% and 42.1% of the patients respectively. Accuracy was worse in non-ischemic cardiomyopathy (NICM) especially for BZ (28.6% vs 55.2%, p = 0.042). Conclusions: Accuracy of standard voltage thresholds for scar and BZ is poor in terms of LPs detection. Diagnostic yield is worse in NICM patients specially for border zone. Springer Verlag https://hdl.handle.net/2445/214271
spellingShingle Accuracy of standard bipolar amplitude voltage thresholds to identify late potential channels in ventricular tachycardia ablation
Roca Luque, Ivo
Taquicàrdia
Ventricles cardíacs
Cicatrius
Malalties del cor
Tachycardia
Ventricle of heart
Scars
Heart diseases
status_str publishedVersion
title Accuracy of standard bipolar amplitude voltage thresholds to identify late potential channels in ventricular tachycardia ablation
title_full Accuracy of standard bipolar amplitude voltage thresholds to identify late potential channels in ventricular tachycardia ablation
title_fullStr Accuracy of standard bipolar amplitude voltage thresholds to identify late potential channels in ventricular tachycardia ablation
title_full_unstemmed Accuracy of standard bipolar amplitude voltage thresholds to identify late potential channels in ventricular tachycardia ablation
title_short Accuracy of standard bipolar amplitude voltage thresholds to identify late potential channels in ventricular tachycardia ablation
title_sort Accuracy of standard bipolar amplitude voltage thresholds to identify late potential channels in ventricular tachycardia ablation
topic Taquicàrdia
Ventricles cardíacs
Cicatrius
Malalties del cor
Tachycardia
Ventricle of heart
Scars
Heart diseases
topic_facet Taquicàrdia
Ventricles cardíacs
Cicatrius
Malalties del cor
Tachycardia
Ventricle of heart
Scars
Heart diseases
url https://hdl.handle.net/2445/214271