Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial

Objective: To compare the anesthetic action of 0.5% bupivacaine in relation to 4% articaine, both with 1:200,000 epinephrine, in the surgical removal of lower third molars. As a secondary objective hemodynamic changes using both anesthetics were analyzed. Study Design: Triple-blind crossover randomi...

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Autores: Sancho Puchades, Manuel; Vílchez Pérez, Miguel-Ángel; Valmaseda Castellón, Eduardo; Paredes García, Jordi; Berini Aytés, Leonardo; Gay Escoda, Cosme
Tipo de documento: Artículo
Estado:Published version
Fecha de publicación:2012
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/52483
Acceso en línea:https://hdl.handle.net/2445/52483
Nivel de acceso:Acceso abierto
Palabra clave:Anestèsia en odontologia
Assaigs clínics
Dolor postoperatori
Dent molar
Anestèsia local
Extracció dental
Anesthesia in dentistry
Clinical trials
Postoperative pain
Molar
Local anesthesia
Teeth extraction
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author Sancho Puchades, Manuel
author2 Vílchez Pérez, Miguel-Ángel
Valmaseda Castellón, Eduardo
Paredes García, Jordi
Berini Aytés, Leonardo
Gay Escoda, Cosme
author2_role author
author
author
author
author
author_browse Berini Aytés, Leonardo
Gay Escoda, Cosme
Paredes García, Jordi
Sancho Puchades, Manuel
Valmaseda Castellón, Eduardo
Vílchez Pérez, Miguel-Ángel
author_facet Sancho Puchades, Manuel
Vílchez Pérez, Miguel-Ángel
Valmaseda Castellón, Eduardo
Paredes García, Jordi
Berini Aytés, Leonardo
Gay Escoda, Cosme
author_role author
collection Dipòsit Digital de la UB
description Objective: To compare the anesthetic action of 0.5% bupivacaine in relation to 4% articaine, both with 1:200,000 epinephrine, in the surgical removal of lower third molars. As a secondary objective hemodynamic changes using both anesthetics were analyzed. Study Design: Triple-blind crossover randomized clinical trial. Eighteen patients underwent bilateral removal of impacted lower third molars using 0.5% bupivacaine or 4% articaine in two different appointments. Preoperative, intraoperative and postoperative variables were recorded. Differences were assessed with McNemar tests and repeated measures ANOVA tests. Results: Both solutions exhibited similar latency times and intraoperative efficacy. Statistical significant lower pain levels were observed with bupivacaine between the fifth (p=0.011) and the ninth (p=0.007) postoperative hours. Bupivacaine provided significantly longer lasting soft tissue anesthesia (p<0.05). Systolic blood pressure and heart rate values were significantly higher with articaine. Conclusions: Bupivacaine could be a valid alternative to articaine especially due to its early postoperative pain prevention ability.
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instname_str Universidad de Barcelona
network_acronym_str ES
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oai_identifier_str oai:diposit.ub.edu:2445/52483
publishDate 2012
publishDateSort 2012
publisher Medicina Oral SL
publisherStr Medicina Oral SL
reponame_str Dipòsit Digital de la UB
spelling Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial Sancho Puchades, Manuel Vílchez Pérez, Miguel-Ángel Valmaseda Castellón, Eduardo Paredes García, Jordi Berini Aytés, Leonardo Gay Escoda, Cosme Anestèsia en odontologia Assaigs clínics Dolor postoperatori Dent molar Anestèsia local Extracció dental Anesthesia in dentistry Clinical trials Postoperative pain Molar Local anesthesia Teeth extraction Objective: To compare the anesthetic action of 0.5% bupivacaine in relation to 4% articaine, both with 1:200,000 epinephrine, in the surgical removal of lower third molars. As a secondary objective hemodynamic changes using both anesthetics were analyzed. Study Design: Triple-blind crossover randomized clinical trial. Eighteen patients underwent bilateral removal of impacted lower third molars using 0.5% bupivacaine or 4% articaine in two different appointments. Preoperative, intraoperative and postoperative variables were recorded. Differences were assessed with McNemar tests and repeated measures ANOVA tests. Results: Both solutions exhibited similar latency times and intraoperative efficacy. Statistical significant lower pain levels were observed with bupivacaine between the fifth (p=0.011) and the ninth (p=0.007) postoperative hours. Bupivacaine provided significantly longer lasting soft tissue anesthesia (p<0.05). Systolic blood pressure and heart rate values were significantly higher with articaine. Conclusions: Bupivacaine could be a valid alternative to articaine especially due to its early postoperative pain prevention ability. Medicina Oral SL https://hdl.handle.net/2445/52483
spellingShingle Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial
Sancho Puchades, Manuel
Anestèsia en odontologia
Assaigs clínics
Dolor postoperatori
Dent molar
Anestèsia local
Extracció dental
Anesthesia in dentistry
Clinical trials
Postoperative pain
Molar
Local anesthesia
Teeth extraction
status_str publishedVersion
title Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial
title_full Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial
title_fullStr Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial
title_full_unstemmed Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial
title_short Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial
title_sort Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial
topic Anestèsia en odontologia
Assaigs clínics
Dolor postoperatori
Dent molar
Anestèsia local
Extracció dental
Anesthesia in dentistry
Clinical trials
Postoperative pain
Molar
Local anesthesia
Teeth extraction
topic_facet Anestèsia en odontologia
Assaigs clínics
Dolor postoperatori
Dent molar
Anestèsia local
Extracció dental
Anesthesia in dentistry
Clinical trials
Postoperative pain
Molar
Local anesthesia
Teeth extraction
url https://hdl.handle.net/2445/52483