Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.
The urochordate Oikopleura dioica is emerging as a nonclassical animal model in the field of evolutionary developmental biology (a.k.a. evo-devo) especially attractive for investigating the impact of gene loss on the evolution of mechanisms of development. This is because this organism fulfills the...
| Authors: | ; ; ; |
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| Format: | Article |
| Status: | Accepted version |
| Publication date: | 2019 |
| Country: | España |
| Institution: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repository: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2445/194908 |
| Online Access: | https://hdl.handle.net/2445/194908 |
| Access Level: | Open access |
| Keyword: | Cordats Biologia del desenvolupament Filogènia Chordata Developmental biology Phylogeny |
| _version_ | 1878739072779812864 |
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| author | Ferrández-Roldán, Alfonso |
| author2 | Martí-Solans, Josep Cañestro García, Cristian Albalat Rodríguez, Ricard |
| author2_role | author author author |
| author_browse | Albalat Rodríguez, Ricard Cañestro García, Cristian Ferrández-Roldán, Alfonso Martí-Solans, Josep |
| author_facet | Ferrández-Roldán, Alfonso Martí-Solans, Josep Cañestro García, Cristian Albalat Rodríguez, Ricard |
| author_role | author |
| collection | Recercat. Dipósit de la Recerca de Catalunya |
| description | The urochordate Oikopleura dioica is emerging as a nonclassical animal model in the field of evolutionary developmental biology (a.k.a. evo-devo) especially attractive for investigating the impact of gene loss on the evolution of mechanisms of development. This is because this organism fulfills the requirements of an animal model (i.e., has a simple and accessible morphology, a short generation time and life span, and affordable culture in the laboratory and amenable experimental manipulation), but also because O. dioica occupies a key phylogenetic position to understand the diversification and origin of our own phylum, the chordates. During its evolution, O. dioica genome has suffered a drastic process of compaction, becoming the smallest known chordate genome, a process that has been accompanied by exacerbating amount of gene losses. Interestingly, however, despite the extensive gene losses, including entire regulatory pathways essential for the embryonic development of other chordates, O. dioica retains the typical chordate body plan. This unexpected situation led to the formulation of the so-called inverse paradox of evo-devo, that is, when a genetic diversity is able to maintain a phenotypic unity. This chapter reviews the biological features of O. dioica as a model animal, along with the current data on the evolution of its genes and genome. We pay special attention to the numerous examples of gene losses that have taken place during the evolution of this unique animal model, which is helping us to understand to which the limits of evo-devo can be pushed off. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_ba96d60f038ef481ecbdeff5b33c1907 |
| institution | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| instname_str | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:recercat.cat:2445/194908 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher | Springer Nature |
| publisherStr | Springer Nature |
| reponame_str | Recercat. Dipósit de la Recerca de Catalunya |
| spelling | Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development. Ferrández-Roldán, Alfonso Martí-Solans, Josep Cañestro García, Cristian Albalat Rodríguez, Ricard Cordats Biologia del desenvolupament Filogènia Chordata Developmental biology Phylogeny The urochordate Oikopleura dioica is emerging as a nonclassical animal model in the field of evolutionary developmental biology (a.k.a. evo-devo) especially attractive for investigating the impact of gene loss on the evolution of mechanisms of development. This is because this organism fulfills the requirements of an animal model (i.e., has a simple and accessible morphology, a short generation time and life span, and affordable culture in the laboratory and amenable experimental manipulation), but also because O. dioica occupies a key phylogenetic position to understand the diversification and origin of our own phylum, the chordates. During its evolution, O. dioica genome has suffered a drastic process of compaction, becoming the smallest known chordate genome, a process that has been accompanied by exacerbating amount of gene losses. Interestingly, however, despite the extensive gene losses, including entire regulatory pathways essential for the embryonic development of other chordates, O. dioica retains the typical chordate body plan. This unexpected situation led to the formulation of the so-called inverse paradox of evo-devo, that is, when a genetic diversity is able to maintain a phenotypic unity. This chapter reviews the biological features of O. dioica as a model animal, along with the current data on the evolution of its genes and genome. We pay special attention to the numerous examples of gene losses that have taken place during the evolution of this unique animal model, which is helping us to understand to which the limits of evo-devo can be pushed off. Springer Nature https://hdl.handle.net/2445/194908 |
| spellingShingle | Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development. Ferrández-Roldán, Alfonso Cordats Biologia del desenvolupament Filogènia Chordata Developmental biology Phylogeny |
| status_str | acceptedVersion |
| title | Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development. |
| title_full | Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development. |
| title_fullStr | Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development. |
| title_full_unstemmed | Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development. |
| title_short | Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development. |
| title_sort | Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development. |
| topic | Cordats Biologia del desenvolupament Filogènia Chordata Developmental biology Phylogeny |
| topic_facet | Cordats Biologia del desenvolupament Filogènia Chordata Developmental biology Phylogeny |
| url | https://hdl.handle.net/2445/194908 |