The prevalence of mild cognitive impairment in diverse geographical and ethnocultural regions: The COSMIC Collaboration

Background Changes in criteria and differences in populations studied and methodology have produced a wide range of prevalence estimates for mild cognitive impairment (MCI). Methods Uniform criteria were applied to harmonized data from 11 studies from USA, Europe, Asia and Australia, and MCI prevale...

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Detalles Bibliográficos
Autores: Sachdev, P.S.; Lipnicki, D.M.; Kochan, N.A.; Crawford, J.D.; Thalamuthu, A.; Andrews, G.; Brayne, C.; Matthews, F.E.; Stephan, B.C.M.; Lipton, R.B.; Katz, M.J.; Ritchie, K.; Carrière, I.; Ancelin, M.L; Lam, L.C.W.; Wong, C.H.Y.; Fung, A.W.T.; Guaita, A.; Vaccaro, R.; Davin, A.; Ganguli, M.; Dodge, H.; Hughes, T.; Anstey, K.J.; Cherbuin, N.; Butterworth, P.; Ng, T.P.; Gao, Q.; Reppermund, S.; Brodaty, H.; Schupf, N.; Manly, J.; Stern, Y.; Lobo, A.; Lopez-Anton, R.; Santabárbara, J.; Zimmerman, M.; Derby, C.; Leung, G.T.Y.; Chan, W.C.; Polito, L.; Abbondanza, S.; Valle, E.; Colombo, M.; Vitali, S.F.; Fossi, S.; Zaccaria, D.; Forloni, G.; Villani, S.; Christensen, H.; MacKinnon, A.; Easteal, S.; Jacomb, T.; Maxwell, K.; Bowman, A.; Burns, K.; Broe, A.; Dekker, J.; Dooley, L.; De Permentier, M.; Fairjones, S.; Fletcher, J.; French, T.; Foster, C.; Nugent-Cleary-Fox, E.; Gooi, C.; Harvey, E.; Helyer, R.; Hsieh, S.; Hughes, L.; Jacek, S.; Johnston, M.; McCade, D.; Meeth, S.; Milne, E.; Moir, A.; O''Grady, R.; Pfaeffli, K.; Pose, C.; Reuser, L.; Rose, A.; Schofield, P.; Shahnawaz, Z.; Sharpley, A.; Thompson, C.; Queisser, W.; Wong, S.; Mayeux, R.; Brickman, A.; Luchsinger, J.; Sanchez, D.; Tang, M.X.; Andrews, H.; Marcos, G.; De-La-Cámara, C.; Saz, P.; Ventura, T.; Quintanilla, M.A.; Lobo, E.
Tipo de documento: Artículo
Estado:Published version
Fecha de publicación:2015
País:España
Institución:Universidad de Zaragoza
Repositorio:Zaguán. Repositorio Digital de la Universidad de Zaragoza
OAI Identifier:oai:zaguan.unizar.es:36762
Acceso en línea:http://zaguan.unizar.es/record/36762
Nivel de acceso:Acceso abierto
Descripción
Sumario:Background Changes in criteria and differences in populations studied and methodology have produced a wide range of prevalence estimates for mild cognitive impairment (MCI). Methods Uniform criteria were applied to harmonized data from 11 studies from USA, Europe, Asia and Australia, and MCI prevalence estimates determined using three separate definitions of cognitive impairment. Results The published range of MCI prevalence estimates was 5.0%-36.7%. This was reduced with all cognitive impairment definitions: performance in the bottom 6.681% (3.2%-10.8%); Clinical Dementia Rating of 0.5 (1.8%-14.9%); Mini-Mental State Examination score of 24-27 (2.1%-20.7%). Prevalences using the first definition were 5.9% overall, and increased with age (P < .001) but were unaffected by sex or the main races/ethnicities investigated (Whites and Chinese). Not completing high school increased the likelihood of MCI (P = .01). Conclusion Applying uniform criteria to harmonized data greatly reduced the variation in MCI prevalence internationally.