Immersive virtual reality-based interventions for chronic neck pain management: A systematic review and meta-analysis.

Chronic neck pain (CNP) is a global health problem characterized by persistent pain, functional disability, and restricted cervical range of motion (ROM). As an adjunct to conventional pharmacotherapy and physiotherapy, immersive virtual reality (IVR) interventions have emerged as a promising clinic...

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Authors: Desdentado-Guillén, José María; González-Lara, Cristina; Guerero-González, Carmen; García-López, Héctor; Obrero-Gaitán, Esteban; Cortés-Pérez, Irene
Format: Article
Status:Published version
Publication date:2026
Country:España
Institution:Universidad de Jaén
Repository:RUJA. Repositorio Institucional de la Producción Científica de la Universidad de Jaén
OAI Identifier:oai:dnet:ruja________::b25d87cb981768b74804ad96b91b2d95
Online Access:https://doi.org/10.1016/j.msksp.2026.1035635
https://www.sciencedirect.com/science/article/pii/S2468781226000792
https://hdl.handle.net/10953/7860
Access Level:Open access
Keyword:Chronic neck pain
Disability
Immersive virtual reality
Meta-analysis
Pain
Virtual reality
Health
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author Desdentado-Guillén, José María
author2 González-Lara, Cristina
Guerero-González, Carmen
García-López, Héctor
Obrero-Gaitán, Esteban
Cortés-Pérez, Irene
author2_role author
author
author
author
author
author_browse Cortés-Pérez, Irene
Desdentado-Guillén, José María
García-López, Héctor
González-Lara, Cristina
Guerero-González, Carmen
Obrero-Gaitán, Esteban
author_facet Desdentado-Guillén, José María
González-Lara, Cristina
Guerero-González, Carmen
García-López, Héctor
Obrero-Gaitán, Esteban
Cortés-Pérez, Irene
author_role author
collection RUJA. Repositorio Institucional de la Producción Científica de la Universidad de Jaén
description Chronic neck pain (CNP) is a global health problem characterized by persistent pain, functional disability, and restricted cervical range of motion (ROM). As an adjunct to conventional pharmacotherapy and physiotherapy, immersive virtual reality (IVR) interventions have emerged as a promising clinical tool for CNP management. The aim of this systematic review with meta-analysis (SRMA) was to assess the effectiveness of IVR in improving pain, disability and cervical ROM and joint position sense (JPS) in patients with CNP. Additionally, to evaluate the effectiveness of IVR in combination with physiotherapy programs or when used as a standalone intervention.
eu_rights_str_mv openAccess
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institution Universidad de Jaén
instname_str Universidad de Jaén
network_acronym_str ES
network_name_str España
oai_identifier_str oai:dnet:ruja________::b25d87cb981768b74804ad96b91b2d95
publishDate 2026
publishDateSort 2026
publisher Elsevier
publisherStr Elsevier
reponame_str RUJA. Repositorio Institucional de la Producción Científica de la Universidad de Jaén
spelling Immersive virtual reality-based interventions for chronic neck pain management: A systematic review and meta-analysis. Desdentado-Guillén, José María González-Lara, Cristina Guerero-González, Carmen García-López, Héctor Obrero-Gaitán, Esteban Cortés-Pérez, Irene Chronic neck pain Disability Immersive virtual reality Meta-analysis Pain Virtual reality Health Chronic neck pain (CNP) is a global health problem characterized by persistent pain, functional disability, and restricted cervical range of motion (ROM). As an adjunct to conventional pharmacotherapy and physiotherapy, immersive virtual reality (IVR) interventions have emerged as a promising clinical tool for CNP management. The aim of this systematic review with meta-analysis (SRMA) was to assess the effectiveness of IVR in improving pain, disability and cervical ROM and joint position sense (JPS) in patients with CNP. Additionally, to evaluate the effectiveness of IVR in combination with physiotherapy programs or when used as a standalone intervention. A systematic literature search was conducted in PubMed Medline, SCOPUS, WOS, CINAHL and PEDro without restrictions from inception up to November 2025. Randomized controlled trials (RCTs) including patients with CNP which a group received IVR and others conventional physiotherapy or usual care were included. Pooled effect was estimated through the Cohen's standardized mean difference in a random-effects model. Nine RCTs were included in this SRMA, providing data from 430 patients with CNP (41 ± 13.7 years old, 67.4% female). Our findings report that IVR is effective in reducing pain (SMD = -0.41; 95% CI -0.76 to -0.07; p = 0.02), disability (SMD = -0.38; 95% CI -0.74 to -0.02; p = 0.037), as well as increasing extension (SMD = 0.34; 95% CI 0.02 to 0.66; p = 0.037) and flexion ROM (SMD = 0.43; 95% CI 0.11 to 0.76; p = 0.01) and JPS during cervical flexion (SMD = -0.56; 95% CI -0.13 to -2.53; p = 0.011). Current evidence suggests that IVR can be effective in improving pain, disability, cervical ROM and JPS in patients with CNP. IVR can be more effective in combination with physiotherapy programs. Limitations related to sample size, performance and detection biases, and heterogeneity between IVR protocols can be considered. Elsevier https://doi.org/10.1016/j.msksp.2026.1035635 https://www.sciencedirect.com/science/article/pii/S2468781226000792 https://hdl.handle.net/10953/7860
spellingShingle Immersive virtual reality-based interventions for chronic neck pain management: A systematic review and meta-analysis.
Desdentado-Guillén, José María
Chronic neck pain
Disability
Immersive virtual reality
Meta-analysis
Pain
Virtual reality
Health
status_str publishedVersion
title Immersive virtual reality-based interventions for chronic neck pain management: A systematic review and meta-analysis.
title_full Immersive virtual reality-based interventions for chronic neck pain management: A systematic review and meta-analysis.
title_fullStr Immersive virtual reality-based interventions for chronic neck pain management: A systematic review and meta-analysis.
title_full_unstemmed Immersive virtual reality-based interventions for chronic neck pain management: A systematic review and meta-analysis.
title_short Immersive virtual reality-based interventions for chronic neck pain management: A systematic review and meta-analysis.
title_sort Immersive virtual reality-based interventions for chronic neck pain management: A systematic review and meta-analysis.
topic Chronic neck pain
Disability
Immersive virtual reality
Meta-analysis
Pain
Virtual reality
Health
topic_facet Chronic neck pain
Disability
Immersive virtual reality
Meta-analysis
Pain
Virtual reality
Health
url https://doi.org/10.1016/j.msksp.2026.1035635
https://www.sciencedirect.com/science/article/pii/S2468781226000792
https://hdl.handle.net/10953/7860