Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up
High-grade gliomas (HGG) are the most frequent primary central nervous system tumors; treatment of HCGs includes surgery and post-operative conformal radiotherapy associated with temozolomide (TMZ or procarbazine/lomustine/vincristine [PCV], specifically in patients with anaplastic oligodendroglioma...
| Authors: | ; ; ; ; ; |
|---|---|
| Format: | Article |
| Publication date: | 2019 |
| Country: | España |
| Institution: | Universidad de Navarra |
| Repository: | Dadun. Depósito Académico Digital de la Universidad de Navarra |
| Language: | English |
| OAI Identifier: | oai:dadun.unav.edu:10171/62285 |
| Online Access: | https://hdl.handle.net/10171/62285 |
| Access Level: | Open access |
| Keyword: | Radiosurgery Cyberknife® Recurrent gliomas Ck-cyberknife Glioblastoma multiforme (gbm) Recurrent gbm Srs |
| _version_ | 1878739025820385280 |
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| author | Sallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50e |
| author2 | Yañez, L. (Loreto)|||/items/87e1e005-2728-4e8b-bdfe-5408173d5dd8 Sallabanda, M. (Morena)|||/items/3668a543-920c-4305-bcfd-13a342c5c06c Santos, M. (Marcos)|||/items/cdb6609e-53ec-491b-acb4-adf7d945a9dd Calvo-Manuel, F.A. (Felipe Ángel)|||/items/b5d6c8b0-2e24-4372-a422-00af59a4cd3e Marsiglia, H. (Hugo)|||/items/57a84eee-bbee-4721-b798-075edc590d0a |
| author2_role | author author author author author |
| author_browse | Calvo-Manuel, F.A. (Felipe Ángel)|||/items/b5d6c8b0-2e24-4372-a422-00af59a4cd3e Marsiglia, H. (Hugo)|||/items/57a84eee-bbee-4721-b798-075edc590d0a Sallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50e Sallabanda, M. (Morena)|||/items/3668a543-920c-4305-bcfd-13a342c5c06c Santos, M. (Marcos)|||/items/cdb6609e-53ec-491b-acb4-adf7d945a9dd Yañez, L. (Loreto)|||/items/87e1e005-2728-4e8b-bdfe-5408173d5dd8 |
| author_facet | Sallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50e Yañez, L. (Loreto)|||/items/87e1e005-2728-4e8b-bdfe-5408173d5dd8 Sallabanda, M. (Morena)|||/items/3668a543-920c-4305-bcfd-13a342c5c06c Santos, M. (Marcos)|||/items/cdb6609e-53ec-491b-acb4-adf7d945a9dd Calvo-Manuel, F.A. (Felipe Ángel)|||/items/b5d6c8b0-2e24-4372-a422-00af59a4cd3e Marsiglia, H. (Hugo)|||/items/57a84eee-bbee-4721-b798-075edc590d0a |
| author_role | author |
| collection | Dadun. Depósito Académico Digital de la Universidad de Navarra |
| description | High-grade gliomas (HGG) are the most frequent primary central nervous system tumors; treatment of HCGs includes surgery and post-operative conformal radiotherapy associated with temozolomide (TMZ or procarbazine/lomustine/vincristine [PCV], specifically in patients with anaplastic oligodendrogliomas or anaplastic oligoastrocytomas). However, recurrence is common. Re-irradiation has been utilized in this setting for years and remains a feasible option, although there is always a concern regarding toxicity. Modern high-precision conformal techniques, including stereotactic radiosurgery (SRS), could improve the therapeutic ratio by delivering high biologically equivalent doses while reducing high-dose radiotherapy (RT) to normal brain tissue. In this paper, we present the results obtained after prolonged follow-up in patients who underwent SRS as a treatment for recurrent high-grade gliomas at San Francisco Hospital in Madrid, Spain. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_b9aed51feb6cae6e3a3f0cebb9cedf68 |
| institution | Universidad de Navarra |
| instname_str | Universidad de Navarra |
| language | eng |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:dadun.unav.edu:10171/62285 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher | Cureus, Inc. |
| publisherStr | Cureus, Inc. |
| reponame_str | Dadun. Depósito Académico Digital de la Universidad de Navarra |
| spelling | Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up Sallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50e Yañez, L. (Loreto)|||/items/87e1e005-2728-4e8b-bdfe-5408173d5dd8 Sallabanda, M. (Morena)|||/items/3668a543-920c-4305-bcfd-13a342c5c06c Santos, M. (Marcos)|||/items/cdb6609e-53ec-491b-acb4-adf7d945a9dd Calvo-Manuel, F.A. (Felipe Ángel)|||/items/b5d6c8b0-2e24-4372-a422-00af59a4cd3e Marsiglia, H. (Hugo)|||/items/57a84eee-bbee-4721-b798-075edc590d0a Radiosurgery Cyberknife® Recurrent gliomas Ck-cyberknife Glioblastoma multiforme (gbm) Recurrent gbm Srs High-grade gliomas (HGG) are the most frequent primary central nervous system tumors; treatment of HCGs includes surgery and post-operative conformal radiotherapy associated with temozolomide (TMZ or procarbazine/lomustine/vincristine [PCV], specifically in patients with anaplastic oligodendrogliomas or anaplastic oligoastrocytomas). However, recurrence is common. Re-irradiation has been utilized in this setting for years and remains a feasible option, although there is always a concern regarding toxicity. Modern high-precision conformal techniques, including stereotactic radiosurgery (SRS), could improve the therapeutic ratio by delivering high biologically equivalent doses while reducing high-dose radiotherapy (RT) to normal brain tissue. In this paper, we present the results obtained after prolonged follow-up in patients who underwent SRS as a treatment for recurrent high-grade gliomas at San Francisco Hospital in Madrid, Spain. Cureus, Inc. https://hdl.handle.net/10171/62285 |
| spellingShingle | Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up Sallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50e Radiosurgery Cyberknife® Recurrent gliomas Ck-cyberknife Glioblastoma multiforme (gbm) Recurrent gbm Srs |
| title | Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title_full | Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title_fullStr | Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title_full_unstemmed | Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title_short | Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title_sort | Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| topic | Radiosurgery Cyberknife® Recurrent gliomas Ck-cyberknife Glioblastoma multiforme (gbm) Recurrent gbm Srs |
| topic_facet | Radiosurgery Cyberknife® Recurrent gliomas Ck-cyberknife Glioblastoma multiforme (gbm) Recurrent gbm Srs |
| url | https://hdl.handle.net/10171/62285 |