Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease
Malnutrition has a negative impact on patients with chronic pulmonary obstructive disease (COPD). The purpose of this study was to assess the prevalence of malnutrition, defined by the Global Leadership Initiative for Malnutrition (GLIM), in stable COPD patients referred to pulmonary rehabilitation,...
| Autores: | ; ; ; ; ; ; ; ; ; ; |
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| Tipo de documento: | Artigo |
| Estado: | Published version |
| Data de publicação: | 2021 |
| País: | España |
| Recursos: | Universitat Pompeu Fabra |
| Repositório: | Repositorio Digital de la UPF |
| OAI Identifier: | oai:repositori.upf.edu:10230/48111 |
| Acesso em linha: | http://hdl.handle.net/10230/48111 http://dx.doi.org/10.3390/nu13020369 |
| Nível de acesso: | Acesso aberto |
| Palavra-chave: | GLIM Chronic pulmonary obstructive disease Hospitalization Malnutrition Mortality Rehabilitation |
| _version_ | 1878738663159889920 |
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| author | Dávalos Yerovi, Vanesa |
| author2 | Marco Navarro, Ester Sánchez-Rodríguez, Dolores Duran Jordà, Xavier, 1974- Meza Valderrama, Delky Rodríguez, Diego Muñoz, Elena Tejero Sánchez, Marta Muns, Maria Dolors Guillén-Solà, Anna Duarte Oller, Esther |
| author2_role | author author author author author author author author author author |
| author_browse | Duarte Oller, Esther Duran Jordà, Xavier, 1974- Dávalos Yerovi, Vanesa Guillén-Solà, Anna Marco Navarro, Ester Meza Valderrama, Delky Muns, Maria Dolors Muñoz, Elena Rodríguez, Diego Sánchez-Rodríguez, Dolores Tejero Sánchez, Marta |
| author_facet | Dávalos Yerovi, Vanesa Marco Navarro, Ester Sánchez-Rodríguez, Dolores Duran Jordà, Xavier, 1974- Meza Valderrama, Delky Rodríguez, Diego Muñoz, Elena Tejero Sánchez, Marta Muns, Maria Dolors Guillén-Solà, Anna Duarte Oller, Esther |
| author_role | author |
| collection | Repositorio Digital de la UPF |
| description | Malnutrition has a negative impact on patients with chronic pulmonary obstructive disease (COPD). The purpose of this study was to assess the prevalence of malnutrition, defined by the Global Leadership Initiative for Malnutrition (GLIM), in stable COPD patients referred to pulmonary rehabilitation, and to explore potential associations of malnutrition according to GLIM, and its components, with increased risk of mortality and hospitalizations in 2 years. In a post-hoc analysis of a prospective cohort of 200 rehabilitation patients with stable COPD, main outcome variables were hospital admissions, length of stay, and mortality during a 2-year follow-up. Covariates were malnutrition according to GLIM and its phenotypic criteria: unintentional weight loss, low body mass index (BMI), and low fat-free mass (FFM). Univariate and multivariate analysis were performed using logistic and proportional hazard Cox regression. Malnutrition according to GLIM showed 45% prevalence and was associated with increased mortality risk. Low age-related BMI and FFM were independently associated with mortality, which persisted after adjustment for age and lung function. Malnutrition and low BMI were also associated with increased risk of hospitalization. Malnutrition according to GLIM criteria was highly prevalent in rehabilitation patients with COPD and was associated with nearly 3 times greater mortality and hospitalization risk. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_b2db31c3c758cb34d5593d982c74973e |
| institution | Universitat Pompeu Fabra |
| instname_str | Universitat Pompeu Fabra |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:repositori.upf.edu:10230/48111 |
| publishDate | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI |
| publisherStr | MDPI |
| reponame_str | Repositorio Digital de la UPF |
| spelling | Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease Dávalos Yerovi, Vanesa Marco Navarro, Ester Sánchez-Rodríguez, Dolores Duran Jordà, Xavier, 1974- Meza Valderrama, Delky Rodríguez, Diego Muñoz, Elena Tejero Sánchez, Marta Muns, Maria Dolors Guillén-Solà, Anna Duarte Oller, Esther GLIM Chronic pulmonary obstructive disease Hospitalization Malnutrition Mortality Rehabilitation Malnutrition has a negative impact on patients with chronic pulmonary obstructive disease (COPD). The purpose of this study was to assess the prevalence of malnutrition, defined by the Global Leadership Initiative for Malnutrition (GLIM), in stable COPD patients referred to pulmonary rehabilitation, and to explore potential associations of malnutrition according to GLIM, and its components, with increased risk of mortality and hospitalizations in 2 years. In a post-hoc analysis of a prospective cohort of 200 rehabilitation patients with stable COPD, main outcome variables were hospital admissions, length of stay, and mortality during a 2-year follow-up. Covariates were malnutrition according to GLIM and its phenotypic criteria: unintentional weight loss, low body mass index (BMI), and low fat-free mass (FFM). Univariate and multivariate analysis were performed using logistic and proportional hazard Cox regression. Malnutrition according to GLIM showed 45% prevalence and was associated with increased mortality risk. Low age-related BMI and FFM were independently associated with mortality, which persisted after adjustment for age and lung function. Malnutrition and low BMI were also associated with increased risk of hospitalization. Malnutrition according to GLIM criteria was highly prevalent in rehabilitation patients with COPD and was associated with nearly 3 times greater mortality and hospitalization risk. MDPI http://hdl.handle.net/10230/48111 http://dx.doi.org/10.3390/nu13020369 |
| spellingShingle | Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease Dávalos Yerovi, Vanesa GLIM Chronic pulmonary obstructive disease Hospitalization Malnutrition Mortality Rehabilitation |
| status_str | publishedVersion |
| title | Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease |
| title_full | Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease |
| title_fullStr | Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease |
| title_full_unstemmed | Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease |
| title_short | Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease |
| title_sort | Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease |
| topic | GLIM Chronic pulmonary obstructive disease Hospitalization Malnutrition Mortality Rehabilitation |
| topic_facet | GLIM Chronic pulmonary obstructive disease Hospitalization Malnutrition Mortality Rehabilitation |
| url | http://hdl.handle.net/10230/48111 http://dx.doi.org/10.3390/nu13020369 |