Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD
Producción Científica
| Authors: | ; ; ; ; ; ; ; ; ; ; ; ; ; |
|---|---|
| Format: | Article |
| Status: | Published version |
| Publication date: | 2020 |
| Country: | España |
| Institution: | Universidad de Valladolid |
| Repository: | UVaDOC. Repositorio Documental de la Universidad de Valladolid |
| OAI Identifier: | oai:uvadoc.uva.es:10324/82126 |
| Online Access: | https://doi.org/10.3389/fmed.2020.615312 https://uvadoc.uva.es/handle/10324/82126 |
| Access Level: | Open access |
| Keyword: | COVID-19 Kidneys - Diseases Riñones - Enfermedades Nephrology Pneumònia Neumonía Acute renal failure Insuficiencia renal aguda 3205.06 Nefrología 32 Ciencias Médicas |
| _version_ | 1878738363767324672 |
|---|---|
| author | Coca Rojo, Armando |
| author2 | Burballa Tarrega, Carla Cristina Centellas-Pérez, Francisco Javier Pérez Saéz, María José Bustamante Munguira, Elena Ortega, Agustín Dueñas, Carlos Arenas, María Dolores Pérez-Martínez, Juan Ruiz, Guadalupe Crespo Barrio, Marta Llamas, Francisco Bustamante Munguira, Juan Pascual Santos, Julio |
| author2_role | author author author author author author author author author author author author author |
| author_browse | Arenas, María Dolores Burballa Tarrega, Carla Cristina Bustamante Munguira, Elena Bustamante Munguira, Juan Centellas-Pérez, Francisco Javier Coca Rojo, Armando Crespo Barrio, Marta Dueñas, Carlos Llamas, Francisco Ortega, Agustín Pascual Santos, Julio Pérez Saéz, María José Pérez-Martínez, Juan Ruiz, Guadalupe |
| author_facet | Coca Rojo, Armando Burballa Tarrega, Carla Cristina Centellas-Pérez, Francisco Javier Pérez Saéz, María José Bustamante Munguira, Elena Ortega, Agustín Dueñas, Carlos Arenas, María Dolores Pérez-Martínez, Juan Ruiz, Guadalupe Crespo Barrio, Marta Llamas, Francisco Bustamante Munguira, Juan Pascual Santos, Julio |
| author_role | author |
| collection | UVaDOC. Repositorio Documental de la Universidad de Valladolid |
| description | Producción Científica |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_adc9e8a5c19e03804ea033fa4484ed5e |
| institution | Universidad de Valladolid |
| instname_str | Universidad de Valladolid |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:uvadoc.uva.es:10324/82126 |
| publishDate | 2020 |
| publishDateSort | 2020 |
| publisher | Frontiers in medicine |
| publisherStr | Frontiers in medicine |
| reponame_str | UVaDOC. Repositorio Documental de la Universidad de Valladolid |
| spelling | Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD Coca Rojo, Armando Burballa Tarrega, Carla Cristina Centellas-Pérez, Francisco Javier Pérez Saéz, María José Bustamante Munguira, Elena Ortega, Agustín Dueñas, Carlos Arenas, María Dolores Pérez-Martínez, Juan Ruiz, Guadalupe Crespo Barrio, Marta Llamas, Francisco Bustamante Munguira, Juan Pascual Santos, Julio COVID-19 Kidneys - Diseases Riñones - Enfermedades Nephrology Pneumònia Neumonía Acute renal failure Insuficiencia renal aguda 3205.06 Nefrología 32 Ciencias Médicas Producción Científica Background: Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome-Corona Virus 2 has generated significant impact on global health worldwide. COVID-19 can cause pneumonia and organ injury. Chronic kidney disease (CKD) has been associated with increased mortality in previous epidemics, but there is a paucity of data regarding actual risks for non-dialysis CKD patients with COVID-19. Methods: Multicenter, observational cohort study including 136 non-dialysis CKD patients and 136 age- and sex-matched controls that required hospitalization due to COVID-19. Patients with end-stage renal disease, a kidney transplant or without registered baseline glomerular filtration rate prior to COVID-19 infection were excluded. CKD and acute kidney injury (AKI) were defined according to KDIGO criteria. Results: CKD patients had higher white blood cell count and D-dimer and lower lymphocyte percentage. No differences were found regarding symptoms on admission. CKD was associated with higher rate of AKI (61 vs. 24.3%) and mortality (40.4 vs. 24.3%). Patients with AKI had the highest hazard for death (AKI/non-CKD HR:7.04, 95% CI:2.87-17.29; AKI/CKD HR:5.25, 95% CI: 2.29-12.02), followed by CKD subjects without AKI (HR:3.39, 95% CI:1.36-8.46). CKD status did not condition ICU admission or length of in-hospital stay. Conclusions: CKD patients that require hospitalization due to COVID-19 are exposed to higher risk of death and AKI. Consejería de Sanidad, Junta de Castilla y León (GRS1732/A/18 and GRS 1969/A/19). Frontiers in medicine https://doi.org/10.3389/fmed.2020.615312 https://uvadoc.uva.es/handle/10324/82126 |
| spellingShingle | Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD Coca Rojo, Armando COVID-19 Kidneys - Diseases Riñones - Enfermedades Nephrology Pneumònia Neumonía Acute renal failure Insuficiencia renal aguda 3205.06 Nefrología 32 Ciencias Médicas |
| status_str | publishedVersion |
| title | Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD |
| title_full | Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD |
| title_fullStr | Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD |
| title_full_unstemmed | Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD |
| title_short | Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD |
| title_sort | Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD |
| topic | COVID-19 Kidneys - Diseases Riñones - Enfermedades Nephrology Pneumònia Neumonía Acute renal failure Insuficiencia renal aguda 3205.06 Nefrología 32 Ciencias Médicas |
| topic_facet | COVID-19 Kidneys - Diseases Riñones - Enfermedades Nephrology Pneumònia Neumonía Acute renal failure Insuficiencia renal aguda 3205.06 Nefrología 32 Ciencias Médicas |
| url | https://doi.org/10.3389/fmed.2020.615312 https://uvadoc.uva.es/handle/10324/82126 |