Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment
Lifestyle interventions have positive neuroprotective effects in aging. However, there are still open questions about how changes in resting-state functional connectivity (rsFC) contribute to cognitive improvements. The Projecte Moviment is a 12-week randomized controlled trial of a multimodal data...
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| Tipo de documento: | Artículo |
| Estado: | Published version |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Fundació Sant Joan de Déu |
| Repositorio: | r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
| OAI Identifier: | oai:fsjd.fundanetsuite.com:p24737 |
| Acceso en línea: | https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=24737 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | Aerobic exercise Computerized cognitive training Combined training fMRI Resting-state functional connectivity Default mode network Multiplexity |
| _version_ | 1878737993847537665 |
|---|---|
| author | Dimitriadis SI |
| author2 | Castells-Sánchez A Roig-Coll F Dacosta-Aguayo R Lamonja-Vicente N Torán-Monserrat P García-Molina A Monte-Rubio G Stillman C Perera-Lluna A Mataró M |
| author2_role | author author author author author author author author author author |
| author_browse | Castells-Sánchez A Dacosta-Aguayo R Dimitriadis SI García-Molina A Lamonja-Vicente N Mataró M Monte-Rubio G Perera-Lluna A Roig-Coll F Stillman C Torán-Monserrat P |
| author_facet | Dimitriadis SI Castells-Sánchez A Roig-Coll F Dacosta-Aguayo R Lamonja-Vicente N Torán-Monserrat P García-Molina A Monte-Rubio G Stillman C Perera-Lluna A Mataró M |
| author_role | author |
| collection | r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
| description | Lifestyle interventions have positive neuroprotective effects in aging. However, there are still open questions about how changes in resting-state functional connectivity (rsFC) contribute to cognitive improvements. The Projecte Moviment is a 12-week randomized controlled trial of a multimodal data acquisition protocol that investigated the effects of aerobic exercise (AE), computerized cognitive training (CCT), and their combination (COMB). An initial list of 109 participants was recruited from which a total of 82 participants (62% female; age = 58.38 +/- 5.47) finished the intervention with a level of adherence > 80%. Only in the COMB group, we revealed an extended network of 33 connections that involved an increased and decreased rsFC within and between the aDMN/pDMN and a reduced rsFC between the bilateral supplementary motor areas and the right thalamus. No global and especially local rsFC changes due to any intervention mediated the cognitive benefits detected in the AE and COMB groups. Projecte Moviment provides evidence of the clinical relevance of lifestyle interventions and the potential benefits when combining them. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_a807f74e5554f5612d7791c59b2e744f |
| institution | Fundació Sant Joan de Déu |
| instname_str | Fundació Sant Joan de Déu |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:fsjd.fundanetsuite.com:p24737 |
| publishDate | 2024 |
| publishDateSort | 2024 |
| publisher | SPRINGER |
| publisherStr | SPRINGER |
| reponame_str | r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
| spelling | Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment Dimitriadis SI Castells-Sánchez A Roig-Coll F Dacosta-Aguayo R Lamonja-Vicente N Torán-Monserrat P García-Molina A Monte-Rubio G Stillman C Perera-Lluna A Mataró M Aerobic exercise Computerized cognitive training Combined training fMRI Resting-state functional connectivity Default mode network Multiplexity Lifestyle interventions have positive neuroprotective effects in aging. However, there are still open questions about how changes in resting-state functional connectivity (rsFC) contribute to cognitive improvements. The Projecte Moviment is a 12-week randomized controlled trial of a multimodal data acquisition protocol that investigated the effects of aerobic exercise (AE), computerized cognitive training (CCT), and their combination (COMB). An initial list of 109 participants was recruited from which a total of 82 participants (62% female; age = 58.38 +/- 5.47) finished the intervention with a level of adherence > 80%. Only in the COMB group, we revealed an extended network of 33 connections that involved an increased and decreased rsFC within and between the aDMN/pDMN and a reduced rsFC between the bilateral supplementary motor areas and the right thalamus. No global and especially local rsFC changes due to any intervention mediated the cognitive benefits detected in the AE and COMB groups. Projecte Moviment provides evidence of the clinical relevance of lifestyle interventions and the potential benefits when combining them. SPRINGER https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=24737 |
| spellingShingle | Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment Dimitriadis SI Aerobic exercise Computerized cognitive training Combined training fMRI Resting-state functional connectivity Default mode network Multiplexity |
| status_str | publishedVersion |
| title | Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment |
| title_full | Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment |
| title_fullStr | Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment |
| title_full_unstemmed | Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment |
| title_short | Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment |
| title_sort | Intrinsic functional brain connectivity changes following aerobic exercise, computerized cognitive training, and their combination in physically inactive healthy late-middle-aged adults: the Projecte Moviment |
| topic | Aerobic exercise Computerized cognitive training Combined training fMRI Resting-state functional connectivity Default mode network Multiplexity |
| topic_facet | Aerobic exercise Computerized cognitive training Combined training fMRI Resting-state functional connectivity Default mode network Multiplexity |
| url | https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=24737 |