Viscosupplementation for the treatment of osteoarthritis. The contribution of EUROVISCO group

Viscosupplementation (VS) is a symptomatic treatment for knee and other joint osteoarthritis (OA). Despite a long history of use, conflicting opinions remain on the best clinical indications and the most appropriate patients to be treated with intra-articular hyaluronic acid (IA-HA), the optimal dos...

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Authors: Conrozier, Thierry; Raman, Raghu; Chevalier, Xavier; Henrotin, Yves; Monfort Faure, Jorge; Diraçoglù, Demirhan; Bard, Hervé; Baron, Dominique; Jerosch, Jörg; Richette, Pascal; Migliore, Alberto
Format: Article
Status:Published version
Publication date:2021
Country:España
Institution:Universitat Pompeu Fabra
Repository:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/53631
Online Access:http://hdl.handle.net/10230/53631
http://dx.doi.org/10.1177/1759720X211018605
Access Level:Open access
Keyword:EUROVISCO
Hip
Hyaluronic acid
Intra-articular injection
Knee
Osteoarthritis
Recommendations
Viscosupplementation
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author Conrozier, Thierry
author2 Raman, Raghu
Chevalier, Xavier
Henrotin, Yves
Monfort Faure, Jorge
Diraçoglù, Demirhan
Bard, Hervé
Baron, Dominique
Jerosch, Jörg
Richette, Pascal
Migliore, Alberto
author2_role author
author
author
author
author
author
author
author
author
author
author_browse Bard, Hervé
Baron, Dominique
Chevalier, Xavier
Conrozier, Thierry
Diraçoglù, Demirhan
Henrotin, Yves
Jerosch, Jörg
Migliore, Alberto
Monfort Faure, Jorge
Raman, Raghu
Richette, Pascal
author_facet Conrozier, Thierry
Raman, Raghu
Chevalier, Xavier
Henrotin, Yves
Monfort Faure, Jorge
Diraçoglù, Demirhan
Bard, Hervé
Baron, Dominique
Jerosch, Jörg
Richette, Pascal
Migliore, Alberto
author_role author
collection Repositorio Digital de la UPF
description Viscosupplementation (VS) is a symptomatic treatment for knee and other joint osteoarthritis (OA). Despite a long history of use, conflicting opinions remain on the best clinical indications and the most appropriate patients to be treated with intra-articular hyaluronic acid (IA-HA), the optimal dosing regimen and the modalities of retreatment. A multidisciplinary committee of European experts on OA (EUROVISCO) was constituted to formulate recommendations, aimed at helping physicians in the decision-making and the optimal achievement of VS. Before each session members were tasked to collate an exhaustive literature review. Level of evidence and strength of recommendation were based on the level of agreement for each item according to the Delphi method. In 2015, a consensus position was proposed for 24 statements. Among those that obtained a consensual agreement, the working group stressed that VS is effective in mild/moderate knee OA but is not an alternative to surgery in advanced OA, and that dosing regimen must be supported by controlled trials. In 2018, two decision algorithms for the retreatment with IA-HA in knee OA were published. Among the key recommendations, the experts recommended to re-treat every year patients with high risk of OA progression, even if not symptomatic. In 2020, EUROVISCO published two sets of recommendations for the design of clinical trials on the disease-modifying effect of VS and for optimizing the results of VS. The working group underlined that an accurate analysis of radiological features and symptoms and a careful clinical examination may improve the chances of success of VS, as well as good technique of injection and the use of imaging guidance. Based on the exhaustive analysis of the literature and their own clinical experience, the EUROVISCO experts offer a wide range of recommendations intended to help practitioners, particularly in certain cases where the specific characteristics of the patients make the therapeutic decision difficult.
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institution Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
network_acronym_str ES
network_name_str España
oai_identifier_str oai:repositori.upf.edu:10230/53631
publishDate 2021
publishDateSort 2021
publisher SAGE Publications
publisherStr SAGE Publications
reponame_str Repositorio Digital de la UPF
spelling Viscosupplementation for the treatment of osteoarthritis. The contribution of EUROVISCO group Conrozier, Thierry Raman, Raghu Chevalier, Xavier Henrotin, Yves Monfort Faure, Jorge Diraçoglù, Demirhan Bard, Hervé Baron, Dominique Jerosch, Jörg Richette, Pascal Migliore, Alberto EUROVISCO Hip Hyaluronic acid Intra-articular injection Knee Osteoarthritis Recommendations Viscosupplementation Viscosupplementation (VS) is a symptomatic treatment for knee and other joint osteoarthritis (OA). Despite a long history of use, conflicting opinions remain on the best clinical indications and the most appropriate patients to be treated with intra-articular hyaluronic acid (IA-HA), the optimal dosing regimen and the modalities of retreatment. A multidisciplinary committee of European experts on OA (EUROVISCO) was constituted to formulate recommendations, aimed at helping physicians in the decision-making and the optimal achievement of VS. Before each session members were tasked to collate an exhaustive literature review. Level of evidence and strength of recommendation were based on the level of agreement for each item according to the Delphi method. In 2015, a consensus position was proposed for 24 statements. Among those that obtained a consensual agreement, the working group stressed that VS is effective in mild/moderate knee OA but is not an alternative to surgery in advanced OA, and that dosing regimen must be supported by controlled trials. In 2018, two decision algorithms for the retreatment with IA-HA in knee OA were published. Among the key recommendations, the experts recommended to re-treat every year patients with high risk of OA progression, even if not symptomatic. In 2020, EUROVISCO published two sets of recommendations for the design of clinical trials on the disease-modifying effect of VS and for optimizing the results of VS. The working group underlined that an accurate analysis of radiological features and symptoms and a careful clinical examination may improve the chances of success of VS, as well as good technique of injection and the use of imaging guidance. Based on the exhaustive analysis of the literature and their own clinical experience, the EUROVISCO experts offer a wide range of recommendations intended to help practitioners, particularly in certain cases where the specific characteristics of the patients make the therapeutic decision difficult. SAGE Publications http://hdl.handle.net/10230/53631 http://dx.doi.org/10.1177/1759720X211018605
spellingShingle Viscosupplementation for the treatment of osteoarthritis. The contribution of EUROVISCO group
Conrozier, Thierry
EUROVISCO
Hip
Hyaluronic acid
Intra-articular injection
Knee
Osteoarthritis
Recommendations
Viscosupplementation
status_str publishedVersion
title Viscosupplementation for the treatment of osteoarthritis. The contribution of EUROVISCO group
title_full Viscosupplementation for the treatment of osteoarthritis. The contribution of EUROVISCO group
title_fullStr Viscosupplementation for the treatment of osteoarthritis. The contribution of EUROVISCO group
title_full_unstemmed Viscosupplementation for the treatment of osteoarthritis. The contribution of EUROVISCO group
title_short Viscosupplementation for the treatment of osteoarthritis. The contribution of EUROVISCO group
title_sort Viscosupplementation for the treatment of osteoarthritis. The contribution of EUROVISCO group
topic EUROVISCO
Hip
Hyaluronic acid
Intra-articular injection
Knee
Osteoarthritis
Recommendations
Viscosupplementation
topic_facet EUROVISCO
Hip
Hyaluronic acid
Intra-articular injection
Knee
Osteoarthritis
Recommendations
Viscosupplementation
url http://hdl.handle.net/10230/53631
http://dx.doi.org/10.1177/1759720X211018605