Exploring the impact of COVID-19 on newborn neurodevelopment: a pilot study.
The COVID-19 pandemic can seize the opportunity to explore the hypothesis of prenatal exposure to viral infections increases the risk for neurodevelopmental disorders. Advancing our knowledge in this regard would improve primary prevention of mental disorders in children. For this pilot study, six-w...
| Autores: | ; ; ; ; ; ; ; ; |
|---|---|
| Tipo de documento: | Artículo |
| Estado: | Published version |
| Fecha de publicación: | 2023 |
| País: | España |
| Institución: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2445/197255 |
| Acceso en línea: | https://hdl.handle.net/2445/197255 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | Neonatologia Factors de risc en les malalties Neonatology Risk factors in diseases |
| _version_ | 1878737597186965504 |
|---|---|
| author | Ayesa Arriola, Rosa |
| author2 | Castro Quintas, Águeda Ortiz García De La Foz, Víctor Miguel Corredera, Margarita San Martín González, Nerea Murillo García, Nancy Neergaard, Karl Fañanás Saura, Lourdes De Las Cuevas Terán, Isabel. |
| author2_role | author author author author author author author author |
| author_browse | Ayesa Arriola, Rosa Castro Quintas, Águeda De Las Cuevas Terán, Isabel. Fañanás Saura, Lourdes Miguel Corredera, Margarita Murillo García, Nancy Neergaard, Karl Ortiz García De La Foz, Víctor San Martín González, Nerea |
| author_facet | Ayesa Arriola, Rosa Castro Quintas, Águeda Ortiz García De La Foz, Víctor Miguel Corredera, Margarita San Martín González, Nerea Murillo García, Nancy Neergaard, Karl Fañanás Saura, Lourdes De Las Cuevas Terán, Isabel. |
| author_role | author |
| collection | Recercat. Dipósit de la Recerca de Catalunya |
| description | The COVID-19 pandemic can seize the opportunity to explore the hypothesis of prenatal exposure to viral infections increases the risk for neurodevelopmental disorders. Advancing our knowledge in this regard would improve primary prevention of mental disorders in children. For this pilot study, six-week-old infants born to mothers exposed (n = 21) or unexposed (n = 21) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were assessed in Santander-Cantabria (Spain) using the Neonatal Behavioral Assessment Scale (NBAS). Groups comparisons were performed to explore the effects that infection and timing of exposure (in terms of the three trimesters of pregnancy). The infants' competencies and performances on the NBAS were generally similar in the exposed and unexposed to SARS-CoV-2 groups. The most significant difference found was a less optimally response to cuddliness (item on the state regulation domain) particularly in infants born to mothers exposed in the third trimester of pregnancy, and in pull-to-sit (item on the motor system domain). Although our interpretations must be careful, these preliminary results highlight the possible association between prenatal SARS-CoV-2 exposure and poorer development in motor skills and infant interactive behavior. Further longitudinal studies are needed to explore these relationships and disentangle the biological mechanisms implicated. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_a2360e7acdbd111d22ae8a7674286d4d |
| institution | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| instname_str | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:recercat.cat:2445/197255 |
| publishDate | 2023 |
| publishDateSort | 2023 |
| publisher | Nature Publishing Group |
| publisherStr | Nature Publishing Group |
| reponame_str | Recercat. Dipósit de la Recerca de Catalunya |
| spelling | Exploring the impact of COVID-19 on newborn neurodevelopment: a pilot study. Ayesa Arriola, Rosa Castro Quintas, Águeda Ortiz García De La Foz, Víctor Miguel Corredera, Margarita San Martín González, Nerea Murillo García, Nancy Neergaard, Karl Fañanás Saura, Lourdes De Las Cuevas Terán, Isabel. Neonatologia Factors de risc en les malalties Neonatology Risk factors in diseases The COVID-19 pandemic can seize the opportunity to explore the hypothesis of prenatal exposure to viral infections increases the risk for neurodevelopmental disorders. Advancing our knowledge in this regard would improve primary prevention of mental disorders in children. For this pilot study, six-week-old infants born to mothers exposed (n = 21) or unexposed (n = 21) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were assessed in Santander-Cantabria (Spain) using the Neonatal Behavioral Assessment Scale (NBAS). Groups comparisons were performed to explore the effects that infection and timing of exposure (in terms of the three trimesters of pregnancy). The infants' competencies and performances on the NBAS were generally similar in the exposed and unexposed to SARS-CoV-2 groups. The most significant difference found was a less optimally response to cuddliness (item on the state regulation domain) particularly in infants born to mothers exposed in the third trimester of pregnancy, and in pull-to-sit (item on the motor system domain). Although our interpretations must be careful, these preliminary results highlight the possible association between prenatal SARS-CoV-2 exposure and poorer development in motor skills and infant interactive behavior. Further longitudinal studies are needed to explore these relationships and disentangle the biological mechanisms implicated. Nature Publishing Group https://hdl.handle.net/2445/197255 |
| spellingShingle | Exploring the impact of COVID-19 on newborn neurodevelopment: a pilot study. Ayesa Arriola, Rosa Neonatologia Factors de risc en les malalties Neonatology Risk factors in diseases |
| status_str | publishedVersion |
| title | Exploring the impact of COVID-19 on newborn neurodevelopment: a pilot study. |
| title_full | Exploring the impact of COVID-19 on newborn neurodevelopment: a pilot study. |
| title_fullStr | Exploring the impact of COVID-19 on newborn neurodevelopment: a pilot study. |
| title_full_unstemmed | Exploring the impact of COVID-19 on newborn neurodevelopment: a pilot study. |
| title_short | Exploring the impact of COVID-19 on newborn neurodevelopment: a pilot study. |
| title_sort | Exploring the impact of COVID-19 on newborn neurodevelopment: a pilot study. |
| topic | Neonatologia Factors de risc en les malalties Neonatology Risk factors in diseases |
| topic_facet | Neonatologia Factors de risc en les malalties Neonatology Risk factors in diseases |
| url | https://hdl.handle.net/2445/197255 |