Multicentric study on total pancreatectomies

Introduction: Total pancreatectomy (TP) is an uncommon operation, with indications that have not been clearly defined and non-standardized postoperative results. We present a national multicentric study on TP and a comparison with the existing literature Methods: A prospective observational study us...

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Autores: Ramia, JM; Martin-Perez, E; Poves, I; Fabregat-Prous, J; Olea, JLY; Sanchez-Bueno, F; Botello-Martinez, F; Briceno, J; Miyar-de Leon, A; Serradilla, M; Moya-Herraiz, A; Secanella, L; Bueno, FS; Serrablo, A; Fabrega, JF; Cabus, SS; Bravo, MAG; Padillo, J; Blanco, L; Balcells, J; Cugat, E; Domingo, MG; Bellvis, LM; Diaz, MDP; Santoyo, JS; Sanchez, B; Georgiev, T; Villegas, T; Pacho, S; Valladares, LD; Rebollar, J; Munoz, MAS; Dominguez, E; Falgueras, L; Artigas, V; Sabater, L; Gil, AG; de Llama, JIM; Manzanet, G; Pino, JC; Sanjuan, JCR; Lluis, F; Ausania, F; Zuloaga, MA; Escartin, J; Salas, M; Domingo, C; de Rojas, EAS; Mateos, JAB; Cebrian, JMF; Cabrera, BP; Valverde, DP; Sanjuanbenito, A; Belmonte, II; Bejarano, N; Borobia, FG; Guinea, PT; Marcano, AL; Arana, FA; Varo, E; Esteban, R; Blas, JL; Navalon, JMJ; Martinez, CF; Collado, ED; Duran, AC; Vicens, JC; Romero, J; Badia, JM; Sanchez, R; Ibanez, RD; Pardo, F; von Hunefeld, CF; Pereira, F; Molina, FG; Prieto, IR; Poza, AA; Gilsanz, C; Albert, JMM; Morcillo, MA; Cortijo, SM; Fernandez, JM; Baquedano, J; Castell, J; Aguilo, J; Bernal, JC; Grp Hosp Participantes
Tipo de documento: Artículo
Estado:Published version
Fecha de publicación:2019
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p7257
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/7257
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066300683&doi=10.1016%2fj.ciresp.2019.04.004&partnerID=40&md5=a8f08e387ca6aadaadf494687c5e7b18
Nivel de acceso:Acceso abierto
Palabra clave:Pancreas
Total pancreatectomy
Surgery
Review
Sumario:Introduction: Total pancreatectomy (TP) is an uncommon operation, with indications that have not been clearly defined and non-standardized postoperative results. We present a national multicentric study on TP and a comparison with the existing literature Methods: A prospective observational study using data from the national registry of patients after pancreaticoduodenectomy and TP performed for any indication during the study period: January 1 to December 31, 2015 Results: 1016 patients were included from 73 hospitals, 112 of whom had undergone TP. The percentage of TP from the total number of cases was 11%. The mean age was 63.5 years, and 57.2% were males. The most frequently suspected radiological diagnosis was pancreatic cancer (58/112 cases). The most common TP technique was "mesentery artery first" (43/112 cases). Venous resections were performed in 23 patients (20.5%). The percentage of postoperative complications within 90 days was 50%, but major complications (>IIIA) were only 20.7%. The overall 90-day mortality was 8% (9 patients). The average stay was 20.7 days. The 3 most frequent definitive histological diagnoses were: adenocarcinoma of the pancreas, intraductal papillary mucinous neoplasm and chronic pancreatitis. The R0 rate was 67.8%. Conclusions: This study shows that the morbidity and mortality results of TP in Spain are similar or superior to previous publications. More precise TP studies are necessary, focused on specific complications such as endocrine insufficiency. (C) 2019 AEC. Published by Elsevier Espana, S.L.U. All rights reserved.

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