Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units
Introduction: Patients with invasive pneumococcal disease (IPD) may require admission into paediatric intensive care units (PICU). The aim of this study is to analyse the epidemiological, clinical, and microbiological characteristics associated with IPD that may require admission to the PICU. Materi...
| Autores: | ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; |
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| Tipo de documento: | Artículo |
| Estado: | Published version |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Fundació Sant Joan de Déu |
| Repositorio: | r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
| OAI Identifier: | oai:fsjd.fundanetsuite.com:p18289 |
| Acceso en línea: | https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=18289 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | Streptococcus pneumoniae Paediatric intensive care Invasive pneumococcal disease |
| _version_ | 1878736341123989504 |
|---|---|
| author | Díaz-Conradi A |
| author2 | García-García JJ Fernández de Sevilla M Ventura PS Domínguez A Moraga Llop F de Sevilla MF González Peris S Ciruela P Campins M Muñoz-Almagro C Esteva C Izquierdo C Uriona S Martínez Osorio J Solé Ribalta A Codina G Soldevila N Salleras Sanmartí L |
| author2_role | author author author author author author author author author author author author author author author author author author |
| author_browse | Campins M Ciruela P Codina G Domínguez A Díaz-Conradi A Esteva C Fernández de Sevilla M García-García JJ González Peris S Izquierdo C Martínez Osorio J Moraga Llop F Muñoz-Almagro C Salleras Sanmartí L Soldevila N Solé Ribalta A Uriona S Ventura PS de Sevilla MF |
| author_facet | Díaz-Conradi A García-García JJ Fernández de Sevilla M Ventura PS Domínguez A Moraga Llop F de Sevilla MF González Peris S Ciruela P Campins M Muñoz-Almagro C Esteva C Izquierdo C Uriona S Martínez Osorio J Solé Ribalta A Codina G Soldevila N Salleras Sanmartí L |
| author_role | author |
| collection | r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
| description | Introduction: Patients with invasive pneumococcal disease (IPD) may require admission into paediatric intensive care units (PICU). The aim of this study is to analyse the epidemiological, clinical, and microbiological characteristics associated with IPD that may require admission to the PICU. Material and methods: A prospective study was conducted on cases of IPD diagnosed in three Paediatric Hospitals in Barcelona between January 2012 and June 2016. An analysis was made of the associations between the admission to PICU and the epidemiological, clinical, and microbiological variables. Results: A total of 263 cases with IPD were included, of which 19% (n = 50) required admission to PICU. Patients with septic shock (7; 100%), meningitis (16; 84.2%), and those with complicated pneumonia (23; 15.2%) were admitted to the PICU. The most frequent complications were pulmonary (35.2%) and neurological (39.5%). The ratio between admission and non-admission to PICU was 4.7 times higher in subjects with an underlying disease. The serotypes associated with PICU admission were 19A (23% of the total of this serotype), serotype 14 (20%), serotype 3 (17%), and serotype 1 (12.5%). Conclusions: IPD required PICU admission in cases of septic shock and meningitis, and less so with complicated pneumonia. The percentage of admissions is greater in children with an underlying disease. Admission into the PICU involves a longer stay, complications during the acute phase, as well as sequelae, particularly neurological ones. The serotypes of the patients that were admitted to PICU were predominantly vaccine serotypes. (C) 2020 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_8d4ec89e1c690e1b23ff8123dcd1043c |
| institution | Fundació Sant Joan de Déu |
| instname_str | Fundació Sant Joan de Déu |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:fsjd.fundanetsuite.com:p18289 |
| publishDate | 2021 |
| publishDateSort | 2021 |
| publisher | EDICIONES DOYMA S A |
| publisherStr | EDICIONES DOYMA S A |
| reponame_str | r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
| spelling | Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units Díaz-Conradi A García-García JJ Fernández de Sevilla M Ventura PS Domínguez A Moraga Llop F de Sevilla MF González Peris S Ciruela P Campins M Muñoz-Almagro C Esteva C Izquierdo C Uriona S Martínez Osorio J Solé Ribalta A Codina G Soldevila N Salleras Sanmartí L Streptococcus pneumoniae Paediatric intensive care Invasive pneumococcal disease Introduction: Patients with invasive pneumococcal disease (IPD) may require admission into paediatric intensive care units (PICU). The aim of this study is to analyse the epidemiological, clinical, and microbiological characteristics associated with IPD that may require admission to the PICU. Material and methods: A prospective study was conducted on cases of IPD diagnosed in three Paediatric Hospitals in Barcelona between January 2012 and June 2016. An analysis was made of the associations between the admission to PICU and the epidemiological, clinical, and microbiological variables. Results: A total of 263 cases with IPD were included, of which 19% (n = 50) required admission to PICU. Patients with septic shock (7; 100%), meningitis (16; 84.2%), and those with complicated pneumonia (23; 15.2%) were admitted to the PICU. The most frequent complications were pulmonary (35.2%) and neurological (39.5%). The ratio between admission and non-admission to PICU was 4.7 times higher in subjects with an underlying disease. The serotypes associated with PICU admission were 19A (23% of the total of this serotype), serotype 14 (20%), serotype 3 (17%), and serotype 1 (12.5%). Conclusions: IPD required PICU admission in cases of septic shock and meningitis, and less so with complicated pneumonia. The percentage of admissions is greater in children with an underlying disease. Admission into the PICU involves a longer stay, complications during the acute phase, as well as sequelae, particularly neurological ones. The serotypes of the patients that were admitted to PICU were predominantly vaccine serotypes. (C) 2020 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U. EDICIONES DOYMA S A https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=18289 |
| spellingShingle | Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units Díaz-Conradi A Streptococcus pneumoniae Paediatric intensive care Invasive pneumococcal disease |
| status_str | publishedVersion |
| title | Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units |
| title_full | Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units |
| title_fullStr | Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units |
| title_full_unstemmed | Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units |
| title_short | Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units |
| title_sort | Characteristics of patients with invasive pneumococcal disease requiring admission to intensive care units |
| topic | Streptococcus pneumoniae Paediatric intensive care Invasive pneumococcal disease |
| topic_facet | Streptococcus pneumoniae Paediatric intensive care Invasive pneumococcal disease |
| url | https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=18289 |