Deoxynivalenol degradation in wheat kernels by exposition to ammonia vapours: A tentative strategy for detoxification

Deoxynivalenol (DON) is a mycotoxin produced mainly by Fusarium species and occurs predominantly in cereal grains such as wheat. Due to its toxic effects, in the European Union DON content in unprocessed cereals and processed cereal-based products for human consumption has been regulated, and recomm...

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Detalhes bibliográficos
Autores: Borràs Vallverdú, Bernat; Ramos Girona, Antonio J.; Marín Sillué, Sònia; Sanchís Almenar, Vicente; Rodríguez Bencomo, Juan José
Tipo de documento: Artigo
Estado:Accepted version
Data de publicação:2020
País:España
Recursos:Universitat de Lleida (UdL)
Repositório:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/69311
Acesso em linha:https://doi.org/10.1016/j.foodcont.2020.107444
http://hdl.handle.net/10459.1/69311
Nível de acesso:Acesso aberto
Palavra-chave:Deoxynivalenol (DON)
Fusarium
Mycotoxin
Detoxification
Descrição
Resumo:Deoxynivalenol (DON) is a mycotoxin produced mainly by Fusarium species and occurs predominantly in cereal grains such as wheat. Due to its toxic effects, in the European Union DON content in unprocessed cereals and processed cereal-based products for human consumption has been regulated, and recommended maximum limits have been established for animal feed. In this study, a method for degrading DON on wheat kernels, by exposition to ammonia (NH3) vapours, was optimized. Results have shown that with a simple treatment with ammonia vapours at 90ºC (for two hours), degradations higher than 75% were achieved in kernels affected by a moderated contamination up to 2000 µg/kg DON. The study of the reaction between DON and NH3 allowed us to tentatively establish the structure of possible degradation products. In addition, in silico evaluation indicated, in general, lower toxicity and biological effects for the degradation products than for DON.