Predictors of psychological distress in breast cancer survivors: A biopsychosocial approach

Objective: A cross‐sectional study was conducted to examine the extent to which perceived social support, cortisol-awaking response (CAR) and tumor necrosis factor alpha (TNF-α) interact to statistically predict psychological distress in breast cancer survivors. Method: Moderation analyses were perf...

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Bibliographic Details
Authors: Pérez Tejada, Joana; Labaka Etxeberria, Ainitze; Pascual Sagastizabal, Eider; Garmendia Rezola, Larraitz; Iruretagoyena, Aizpea; Arregi Agirre, Amaia
Format: Article
Publication date:2019
Country:España
Institution:Universidad del País Vasco
Repository:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/70781
Online Access:http://hdl.handle.net/10810/70781
Access Level:Open access
Keyword:breast cancer survivors
psychological distress
social support
TNF-α
CAR
Description
Summary:Objective: A cross‐sectional study was conducted to examine the extent to which perceived social support, cortisol-awaking response (CAR) and tumor necrosis factor alpha (TNF-α) interact to statistically predict psychological distress in breast cancer survivors. Method: Moderation analyses were performed to study the influence of some psychobiological variables on psychological distress. The sample was comprised by 80 survivor women. Results: TNF-α moderate the relation between social support and psychological distress, with both high and moderate levels being significant. In relation to age, a negative association between social support and psychological distress was found only in younger and middle women, whilst lower levels of CAR were associated with psychological distress in older breast cancer survivors. Conclusion: This study provides a biopsychosocial approach about the predictors of psychological distress among breast cancer survivors. Social support interventions during and after treatment may help to improve women’s longer-term health and quality of live during survivorship.