Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study
PurposeApproximately 15-50% of patients with an anorectal abscess will develop an anal fistula, but the true incidence of this entity is currently unknown. The aim of the study was to determine the incidence of anorectal abscess and development of a fistula in a specific population area and to ident...
| Autores: | ; ; ; ; ; ; ; |
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| Tipo de documento: | Artículo |
| Estado: | Published version |
| Fecha de publicación: | 2023 |
| País: | España |
| Institución: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/205224 |
| Acceso en línea: | https://hdl.handle.net/2445/205224 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | Fístules Abscessos Fistula Abscess |
| _version_ | 1878735134897733633 |
|---|---|
| author | Sánchez Haro, Edward |
| author2 | Vela, Emili Cleries, Montserrat Vela Bernal, Sandra Tapiolas, Ingrid Troya Díaz, José Julián Ibáñez, Joan Francesc Parés Martínez, David |
| author2_role | author author author author author author author |
| author_browse | Cleries, Montserrat Julián Ibáñez, Joan Francesc Parés Martínez, David Sánchez Haro, Edward Tapiolas, Ingrid Troya Díaz, José Vela Bernal, Sandra Vela, Emili |
| author_facet | Sánchez Haro, Edward Vela, Emili Cleries, Montserrat Vela Bernal, Sandra Tapiolas, Ingrid Troya Díaz, José Julián Ibáñez, Joan Francesc Parés Martínez, David |
| author_role | author |
| collection | Dipòsit Digital de la UB |
| description | PurposeApproximately 15-50% of patients with an anorectal abscess will develop an anal fistula, but the true incidence of this entity is currently unknown. The aim of the study was to determine the incidence of anorectal abscess and development of a fistula in a specific population area and to identify potential risk factors associated with demographic, socioeconomic and pre-existing disease (e.g. diabetes and inflammatory bowel disease).MethodsA longitudinal observational study was designed including a large cohort study in an area with 7,553,650 inhabitants in Spain 1st january 2014 to 31st december 2019. Adults who attended for the first time with an anorectal abscess and had a minimum of 1-year follow-up were included. The diagnosis was made using ICD-10 codes for anorectal abscess and anal fistula.ResultsDuring the study period, we included 27,821 patients with anorectal abscess. There was a predominance of men (70%) and an overall incidence of 596 per million population. The overall incidence of anal fistula developing from abscesses was 20%, with predominance in men, and a lower incidence in the lowest income level. The cumulative incidence of fistula was higher in men and in younger patients (p < 0.0001). On multivariate analysis, patients aged 60-69 years (hazard ratio 2.0) and those with inflammatory bowel disease (hazard ratio 1.8-2.0) had a strong association with fistula development (hazard ratio 2.0).ConclusionsOne in five patients with an anorectal abscess will develop a fistula, with a higher likelihood in men. Fistula formation was strongly associated with inflammatory bowel disease. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_76b6a6971e69b0cd2b30ea96a9b0eaec |
| institution | Universidad de Barcelona |
| instname_str | Universidad de Barcelona |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:diposit.ub.edu:2445/205224 |
| publishDate | 2023 |
| publishDateSort | 2023 |
| publisher | Springer Science and Business Media LLC |
| publisherStr | Springer Science and Business Media LLC |
| reponame_str | Dipòsit Digital de la UB |
| spelling | Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study Sánchez Haro, Edward Vela, Emili Cleries, Montserrat Vela Bernal, Sandra Tapiolas, Ingrid Troya Díaz, José Julián Ibáñez, Joan Francesc Parés Martínez, David Fístules Abscessos Fistula Abscess PurposeApproximately 15-50% of patients with an anorectal abscess will develop an anal fistula, but the true incidence of this entity is currently unknown. The aim of the study was to determine the incidence of anorectal abscess and development of a fistula in a specific population area and to identify potential risk factors associated with demographic, socioeconomic and pre-existing disease (e.g. diabetes and inflammatory bowel disease).MethodsA longitudinal observational study was designed including a large cohort study in an area with 7,553,650 inhabitants in Spain 1st january 2014 to 31st december 2019. Adults who attended for the first time with an anorectal abscess and had a minimum of 1-year follow-up were included. The diagnosis was made using ICD-10 codes for anorectal abscess and anal fistula.ResultsDuring the study period, we included 27,821 patients with anorectal abscess. There was a predominance of men (70%) and an overall incidence of 596 per million population. The overall incidence of anal fistula developing from abscesses was 20%, with predominance in men, and a lower incidence in the lowest income level. The cumulative incidence of fistula was higher in men and in younger patients (p < 0.0001). On multivariate analysis, patients aged 60-69 years (hazard ratio 2.0) and those with inflammatory bowel disease (hazard ratio 1.8-2.0) had a strong association with fistula development (hazard ratio 2.0).ConclusionsOne in five patients with an anorectal abscess will develop a fistula, with a higher likelihood in men. Fistula formation was strongly associated with inflammatory bowel disease. Springer Science and Business Media LLC https://hdl.handle.net/2445/205224 |
| spellingShingle | Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study Sánchez Haro, Edward Fístules Abscessos Fistula Abscess |
| status_str | publishedVersion |
| title | Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study |
| title_full | Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study |
| title_fullStr | Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study |
| title_full_unstemmed | Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study |
| title_short | Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study |
| title_sort | Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study |
| topic | Fístules Abscessos Fistula Abscess |
| topic_facet | Fístules Abscessos Fistula Abscess |
| url | https://hdl.handle.net/2445/205224 |