Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries
BackgroundIrritable bowel syndrome with predominant constipation (IBS-C) is a complex disorder with gastrointestinal and nervous system components. The study aim was to assess the economic burden of moderate to severe IBS-C in six European countries (France, Germany, Italy, Spain, Sweden and the UK)...
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| Tipo de documento: | Artículo |
| Estado: | Published version |
| Fecha de publicación: | 2019 |
| País: | España |
| Institución: | Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau) |
| Repositorio: | r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau |
| OAI Identifier: | oai:iibsantpau.fundanetsuite.com:p13821 |
| Acceso en línea: | https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13821 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | IBS IBS-C Economic analysis Healthcare resource utilisation Europe |
| _version_ | 1878734913063092224 |
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| author | Tack, J |
| author2 | Stanghellini, V Mearin, F Yiannakou, Y Layer, P Coffin, B Simren, M Mackinnon, J Wiseman, G Marciniak, A Bouchoucha Ducrotte Macaigne Mion Schneider Le Sidanier Tardy Zerbib Andresen Bischoff Jander Jung Krammer Langhorst Omankowsky Schiefke Steuer Van der Voort Von Arnim Annese Cuomo De Angelis Di Mario Di Stefano Ferrini Gasbarrini Giaccobe Marchi Marzio Repici Savarino Angos Berdier Brotons Caballero-Plasencia Clave Fort Garcia Gomez Martinez Perello Rey Sanchez-Antolin Serra Tantina Toran Ekesbo Hellstrom Kjellstrom Lindberg Walter Arebi Bridger Butt Emmanuel Eugenicos Kaushik Millar Sanders Whorwell |
| author2_role | author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| author_browse | Andresen Angos Annese Arebi Berdier Bischoff Bouchoucha Bridger Brotons Butt Caballero-Plasencia Clave Coffin, B Cuomo De Angelis Di Mario Di Stefano Ducrotte Ekesbo Emmanuel Eugenicos Ferrini Fort Garcia Gasbarrini Giaccobe Gomez Hellstrom Jander Jung Kaushik Kjellstrom Krammer Langhorst Layer, P Le Sidanier Lindberg Macaigne Mackinnon, J Marchi Marciniak, A Martinez Marzio Mearin, F Millar Mion Omankowsky Perello Repici Rey Sanchez-Antolin Sanders Savarino Schiefke Schneider Serra Simren, M Stanghellini, V Steuer Tack, J Tantina Tardy Toran Van der Voort Von Arnim Walter Whorwell Wiseman, G Yiannakou, Y Zerbib |
| author_facet | Tack, J Stanghellini, V Mearin, F Yiannakou, Y Layer, P Coffin, B Simren, M Mackinnon, J Wiseman, G Marciniak, A Bouchoucha Ducrotte Macaigne Mion Schneider Le Sidanier Tardy Zerbib Andresen Bischoff Jander Jung Krammer Langhorst Omankowsky Schiefke Steuer Van der Voort Von Arnim Annese Cuomo De Angelis Di Mario Di Stefano Ferrini Gasbarrini Giaccobe Marchi Marzio Repici Savarino Angos Berdier Brotons Caballero-Plasencia Clave Fort Garcia Gomez Martinez Perello Rey Sanchez-Antolin Serra Tantina Toran Ekesbo Hellstrom Kjellstrom Lindberg Walter Arebi Bridger Butt Emmanuel Eugenicos Kaushik Millar Sanders Whorwell |
| author_role | author |
| collection | r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau |
| description | BackgroundIrritable bowel syndrome with predominant constipation (IBS-C) is a complex disorder with gastrointestinal and nervous system components. The study aim was to assess the economic burden of moderate to severe IBS-C in six European countries (France, Germany, Italy, Spain, Sweden and the UK).MethodsAn observational, one year retrospective-prospective (6months each) study of patients diagnosed in the last five years with IBS-C (Rome III criteria) and moderate to severe disease at inclusion (IBS Symptom Severity Scale score175). The primary objective was to assess the direct cost to European healthcare systems.ResultsFive hundred twenty-five patients were included, 60% (range: 43.1-78.8%) suffered from severe IBS-C. During follow-up 11.1-24.0% of patients had a hospitalisation/emergency room (ER) visit, median stay range: 1.5-12.0days and 41.1-90.4% took prescription drugs for IBS-C. 21.4-50.8% of employed patients took sick leave (mean: 11.6-64.1days). The mean annual direct cost to the healthcare systems was Euro937.1- Euro2108.0. The total direct cost (combined costs to healthcare systems and patient) for IBS-C was Euro1421.7-Euro2487.1.ConclusionsIBS-C is not a life-threatening condition; however, it has large impact on healthcare systems and society. Direct and indirect costs for moderate to severe IBS-C were high with the largest direct cost driver being hospitalisations/ER visits. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_724f72d4e76dbd519aaec7a152a1fa05 |
| institution | Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau) |
| instname_str | Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:iibsantpau.fundanetsuite.com:p13821 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher | BMC |
| publisherStr | BMC |
| reponame_str | r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau |
| spelling | Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries Tack, J Stanghellini, V Mearin, F Yiannakou, Y Layer, P Coffin, B Simren, M Mackinnon, J Wiseman, G Marciniak, A Bouchoucha Ducrotte Macaigne Mion Schneider Le Sidanier Tardy Zerbib Andresen Bischoff Jander Jung Krammer Langhorst Omankowsky Schiefke Steuer Van der Voort Von Arnim Annese Cuomo De Angelis Di Mario Di Stefano Ferrini Gasbarrini Giaccobe Marchi Marzio Repici Savarino Angos Berdier Brotons Caballero-Plasencia Clave Fort Garcia Gomez Martinez Perello Rey Sanchez-Antolin Serra Tantina Toran Ekesbo Hellstrom Kjellstrom Lindberg Walter Arebi Bridger Butt Emmanuel Eugenicos Kaushik Millar Sanders Whorwell IBS IBS-C Economic analysis Healthcare resource utilisation Europe BackgroundIrritable bowel syndrome with predominant constipation (IBS-C) is a complex disorder with gastrointestinal and nervous system components. The study aim was to assess the economic burden of moderate to severe IBS-C in six European countries (France, Germany, Italy, Spain, Sweden and the UK).MethodsAn observational, one year retrospective-prospective (6months each) study of patients diagnosed in the last five years with IBS-C (Rome III criteria) and moderate to severe disease at inclusion (IBS Symptom Severity Scale score175). The primary objective was to assess the direct cost to European healthcare systems.ResultsFive hundred twenty-five patients were included, 60% (range: 43.1-78.8%) suffered from severe IBS-C. During follow-up 11.1-24.0% of patients had a hospitalisation/emergency room (ER) visit, median stay range: 1.5-12.0days and 41.1-90.4% took prescription drugs for IBS-C. 21.4-50.8% of employed patients took sick leave (mean: 11.6-64.1days). The mean annual direct cost to the healthcare systems was Euro937.1- Euro2108.0. The total direct cost (combined costs to healthcare systems and patient) for IBS-C was Euro1421.7-Euro2487.1.ConclusionsIBS-C is not a life-threatening condition; however, it has large impact on healthcare systems and society. Direct and indirect costs for moderate to severe IBS-C were high with the largest direct cost driver being hospitalisations/ER visits. BMC https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13821 |
| spellingShingle | Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries Tack, J IBS IBS-C Economic analysis Healthcare resource utilisation Europe |
| status_str | publishedVersion |
| title | Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries |
| title_full | Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries |
| title_fullStr | Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries |
| title_full_unstemmed | Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries |
| title_short | Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries |
| title_sort | Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries |
| topic | IBS IBS-C Economic analysis Healthcare resource utilisation Europe |
| topic_facet | IBS IBS-C Economic analysis Healthcare resource utilisation Europe |
| url | https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13821 |