Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)

OBJECTIVE: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. METHODS: A...

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Authors: Dell'Osso, Bernardo; Benatti, Beatrice; Arici, Chiara; Palazzo, Carlotta; Altamura, A. Carlo; Hollander, Eric, 1957-; Fineberg, Naomi; Stein, Dan J., 1962-; Nicolini, Humberto; Lanzagorta, Nuria; Marazziti, Donatella; Pallanti, Stefano; van Ameringen, Michael; Lochner, Christine; Karamustafalioglu, Oguz; Hranov, Luchezar; Figee, Martin; Drummond, Lynne M.; Rodriguez, Carolyn I.; Grant, John; Denys, Damiaan; Menchón Magriñá, José Manuel; Zohar, Joseph
Format: Article
Status:Accepted version
Publication date:2018
Country:España
Institution:Universidad de Barcelona
Repository:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/140066
Online Access:https://hdl.handle.net/2445/140066
Access Level:Open access
Keyword:Neurosi obsessiva
Suïcidi
Factors de risc en les malalties
Obsessive-compulsive disorder
Suicide
Risk factors in diseases
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author Dell'Osso, Bernardo
author2 Benatti, Beatrice
Arici, Chiara
Palazzo, Carlotta
Altamura, A. Carlo
Hollander, Eric, 1957-
Fineberg, Naomi
Stein, Dan J., 1962-
Nicolini, Humberto
Lanzagorta, Nuria
Marazziti, Donatella
Pallanti, Stefano
van Ameringen, Michael
Lochner, Christine
Karamustafalioglu, Oguz
Hranov, Luchezar
Figee, Martin
Drummond, Lynne M.
Rodriguez, Carolyn I.
Grant, John
Denys, Damiaan
Menchón Magriñá, José Manuel
Zohar, Joseph
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_browse Altamura, A. Carlo
Arici, Chiara
Benatti, Beatrice
Dell'Osso, Bernardo
Denys, Damiaan
Drummond, Lynne M.
Figee, Martin
Fineberg, Naomi
Grant, John
Hollander, Eric, 1957-
Hranov, Luchezar
Karamustafalioglu, Oguz
Lanzagorta, Nuria
Lochner, Christine
Marazziti, Donatella
Menchón Magriñá, José Manuel
Nicolini, Humberto
Palazzo, Carlotta
Pallanti, Stefano
Rodriguez, Carolyn I.
Stein, Dan J., 1962-
Zohar, Joseph
van Ameringen, Michael
author_facet Dell'Osso, Bernardo
Benatti, Beatrice
Arici, Chiara
Palazzo, Carlotta
Altamura, A. Carlo
Hollander, Eric, 1957-
Fineberg, Naomi
Stein, Dan J., 1962-
Nicolini, Humberto
Lanzagorta, Nuria
Marazziti, Donatella
Pallanti, Stefano
van Ameringen, Michael
Lochner, Christine
Karamustafalioglu, Oguz
Hranov, Luchezar
Figee, Martin
Drummond, Lynne M.
Rodriguez, Carolyn I.
Grant, John
Denys, Damiaan
Menchón Magriñá, José Manuel
Zohar, Joseph
author_role author
collection Dipòsit Digital de la UB
description OBJECTIVE: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. METHODS: A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson's chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable. RESULTS: 14.6% of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17%, p<0.001; particularly tic disorder), medical disorders (51 vs. 15%, p<0.001), and previous hospitalizations (62 vs. 11%, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39%, respectively) compared to North American and Middle-Eastern individuals (13 and 8%, respectively) (χ2=11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables. CONCLUSIONS: Our international study found a history of SA prevalence of ~15% in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients.
eu_rights_str_mv openAccess
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institution Universidad de Barcelona
instname_str Universidad de Barcelona
network_acronym_str ES
network_name_str España
oai_identifier_str oai:diposit.ub.edu:2445/140066
publishDate 2018
publishDateSort 2018
publisher Cambridge University Press
publisherStr Cambridge University Press
reponame_str Dipòsit Digital de la UB
spelling Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) Dell'Osso, Bernardo Benatti, Beatrice Arici, Chiara Palazzo, Carlotta Altamura, A. Carlo Hollander, Eric, 1957- Fineberg, Naomi Stein, Dan J., 1962- Nicolini, Humberto Lanzagorta, Nuria Marazziti, Donatella Pallanti, Stefano van Ameringen, Michael Lochner, Christine Karamustafalioglu, Oguz Hranov, Luchezar Figee, Martin Drummond, Lynne M. Rodriguez, Carolyn I. Grant, John Denys, Damiaan Menchón Magriñá, José Manuel Zohar, Joseph Neurosi obsessiva Suïcidi Factors de risc en les malalties Obsessive-compulsive disorder Suicide Risk factors in diseases OBJECTIVE: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. METHODS: A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson's chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable. RESULTS: 14.6% of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17%, p<0.001; particularly tic disorder), medical disorders (51 vs. 15%, p<0.001), and previous hospitalizations (62 vs. 11%, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39%, respectively) compared to North American and Middle-Eastern individuals (13 and 8%, respectively) (χ2=11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables. CONCLUSIONS: Our international study found a history of SA prevalence of ~15% in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients. Cambridge University Press https://hdl.handle.net/2445/140066
spellingShingle Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
Dell'Osso, Bernardo
Neurosi obsessiva
Suïcidi
Factors de risc en les malalties
Obsessive-compulsive disorder
Suicide
Risk factors in diseases
status_str acceptedVersion
title Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
title_full Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
title_fullStr Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
title_full_unstemmed Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
title_short Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
title_sort Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
topic Neurosi obsessiva
Suïcidi
Factors de risc en les malalties
Obsessive-compulsive disorder
Suicide
Risk factors in diseases
topic_facet Neurosi obsessiva
Suïcidi
Factors de risc en les malalties
Obsessive-compulsive disorder
Suicide
Risk factors in diseases
url https://hdl.handle.net/2445/140066