Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring
Allergoid–mannan conjugates are novel vaccines for allergen-specific immunotherapy being currently assayed in phase 2 clinical trials. Allergoid–mannan conjugates target dendritic cells (DCs) and generate functional forkhead box P3 (FOXP3)-positive Treg cells, but their capacity to reprogram monocyt...
| Autores: | ; ; ; ; ; ; |
|---|---|
| Tipo de documento: | Artículo |
| Fecha de publicación: | 2022 |
| País: | España |
| Institución: | Universidad Complutense de Madrid (UCM) |
| Repositorio: | Docta Complutense |
| Lenguaje: | Inglés |
| OAI Identifier: | oai:docta.ucm.es:20.500.14352/71283 |
| Acceso en línea: | https://hdl.handle.net/20.500.14352/71283 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | 577.1 Allergen-specific immunotherapy allergoid–mannan conjugates monocytes tolerogenic dendritic cells regulatory T cells metabolism epigenetics Química Biología molecular (Química) Bioquímica (Química) 23 Química |
| _version_ | 1878734360407965696 |
|---|---|
| author | Benito Villalvilla, Cristina |
| author2 | Pérez Diego, Mario Angelina Querencias, Alba Kisand, Kai Rebane, Ana Subiza, José Luis Palomares Gracia, Óscar |
| author2_role | author author author author author author |
| author_browse | Angelina Querencias, Alba Benito Villalvilla, Cristina Kisand, Kai Palomares Gracia, Óscar Pérez Diego, Mario Rebane, Ana Subiza, José Luis |
| author_facet | Benito Villalvilla, Cristina Pérez Diego, Mario Angelina Querencias, Alba Kisand, Kai Rebane, Ana Subiza, José Luis Palomares Gracia, Óscar |
| author_role | author |
| collection | Docta Complutense |
| description | Allergoid–mannan conjugates are novel vaccines for allergen-specific immunotherapy being currently assayed in phase 2 clinical trials. Allergoid–mannan conjugates target dendritic cells (DCs) and generate functional forkhead box P3 (FOXP3)-positive Treg cells, but their capacity to reprogram monocyte differentiation remains unknown. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_687d5bfdf77c2d34767013e8a0c2d9c1 |
| institution | Universidad Complutense de Madrid (UCM) |
| instname_str | Universidad Complutense de Madrid (UCM) |
| language | eng |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:docta.ucm.es:20.500.14352/71283 |
| publishDate | 2022 |
| publishDateSort | 2022 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| reponame_str | Docta Complutense |
| spelling | Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring Benito Villalvilla, Cristina Pérez Diego, Mario Angelina Querencias, Alba Kisand, Kai Rebane, Ana Subiza, José Luis Palomares Gracia, Óscar 577.1 Allergen-specific immunotherapy allergoid–mannan conjugates monocytes tolerogenic dendritic cells regulatory T cells metabolism epigenetics Química Biología molecular (Química) Bioquímica (Química) 23 Química Allergoid–mannan conjugates are novel vaccines for allergen-specific immunotherapy being currently assayed in phase 2 clinical trials. Allergoid–mannan conjugates target dendritic cells (DCs) and generate functional forkhead box P3 (FOXP3)-positive Treg cells, but their capacity to reprogram monocyte differentiation remains unknown. Elsevier https://hdl.handle.net/20.500.14352/71283 |
| spellingShingle | Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring Benito Villalvilla, Cristina 577.1 Allergen-specific immunotherapy allergoid–mannan conjugates monocytes tolerogenic dendritic cells regulatory T cells metabolism epigenetics Química Biología molecular (Química) Bioquímica (Química) 23 Química |
| title | Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring |
| title_full | Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring |
| title_fullStr | Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring |
| title_full_unstemmed | Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring |
| title_short | Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring |
| title_sort | Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring |
| topic | 577.1 Allergen-specific immunotherapy allergoid–mannan conjugates monocytes tolerogenic dendritic cells regulatory T cells metabolism epigenetics Química Biología molecular (Química) Bioquímica (Química) 23 Química |
| topic_facet | 577.1 Allergen-specific immunotherapy allergoid–mannan conjugates monocytes tolerogenic dendritic cells regulatory T cells metabolism epigenetics Química Biología molecular (Química) Bioquímica (Química) 23 Química |
| url | https://hdl.handle.net/20.500.14352/71283 |