A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment
Native collagen scaffolds were prepared in this work, in which both materials and environmental approaches were considered with the aim of providing a global strategy towards more sustainable biomaterials. From the environmental perspective, it is worth mentioning that acid and enzymatic treatments...
| Autores: | ; ; ; ; ; |
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| Tipo de documento: | Artículo |
| Fecha de publicación: | 2020 |
| País: | España |
| Institución: | Universidad del País Vasco |
| Repositorio: | Addi. Archivo Digital para la Docencia y la Investigación |
| OAI Identifier: | oai:addi.ehu.eus:10810/45848 |
| Acceso en línea: | http://hdl.handle.net/10810/45848 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | native collagen chitosan scaffolds environmental assessment degradation |
| _version_ | 1878734206431920128 |
|---|---|
| author | Andonegui San Martín, Mireia |
| author2 | Irastorza, Ainhoa Izeta Permisán, Ander Cabezudo Maeso, Sara De la Caba Ciriza, María Coro Guerrero Manso, Pedro Manuel |
| author2_role | author author author author author |
| author_browse | Andonegui San Martín, Mireia Cabezudo Maeso, Sara De la Caba Ciriza, María Coro Guerrero Manso, Pedro Manuel Irastorza, Ainhoa Izeta Permisán, Ander |
| author_facet | Andonegui San Martín, Mireia Irastorza, Ainhoa Izeta Permisán, Ander Cabezudo Maeso, Sara De la Caba Ciriza, María Coro Guerrero Manso, Pedro Manuel |
| author_role | author |
| collection | Addi. Archivo Digital para la Docencia y la Investigación |
| description | Native collagen scaffolds were prepared in this work, in which both materials and environmental approaches were considered with the aim of providing a global strategy towards more sustainable biomaterials. From the environmental perspective, it is worth mentioning that acid and enzymatic treatments have been avoided to extract collagen, allowing the reduction in the use of resources, in terms of chemicals, energy, and time, and leading to a low environmental load of this step in all the impact categories under analysis. With the incorporation of chitosan into the scaffold-forming formulations, physical interactions occurred between collagen and chitosan, but the native collagen structure was preserved, as observed by Fourier transform infrared (FTIR) and X-ray diffraction (XRD) analyses. The incorporation of chitosan also led to more homogenous porous microstructures, with higher elastic moduli and compression resistance for both dry and hydrated scaffolds. Furthermore, hydrated scaffolds preserved their size and shape after some compression cycles. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_656609433be3f8108a3f5e9c8b2b53ce |
| institution | Universidad del País Vasco |
| instname_str | Universidad del País Vasco |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:addi.ehu.eus:10810/45848 |
| publishDate | 2020 |
| publishDateSort | 2020 |
| publisher | MDPI |
| publisherStr | MDPI |
| reponame_str | Addi. Archivo Digital para la Docencia y la Investigación |
| spelling | A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment Andonegui San Martín, Mireia Irastorza, Ainhoa Izeta Permisán, Ander Cabezudo Maeso, Sara De la Caba Ciriza, María Coro Guerrero Manso, Pedro Manuel native collagen chitosan scaffolds environmental assessment degradation Native collagen scaffolds were prepared in this work, in which both materials and environmental approaches were considered with the aim of providing a global strategy towards more sustainable biomaterials. From the environmental perspective, it is worth mentioning that acid and enzymatic treatments have been avoided to extract collagen, allowing the reduction in the use of resources, in terms of chemicals, energy, and time, and leading to a low environmental load of this step in all the impact categories under analysis. With the incorporation of chitosan into the scaffold-forming formulations, physical interactions occurred between collagen and chitosan, but the native collagen structure was preserved, as observed by Fourier transform infrared (FTIR) and X-ray diffraction (XRD) analyses. The incorporation of chitosan also led to more homogenous porous microstructures, with higher elastic moduli and compression resistance for both dry and hydrated scaffolds. Furthermore, hydrated scaffolds preserved their size and shape after some compression cycles. This research was funded by the Ministry of Science, Innovation and Universities (RTI2018-097100-B-C22) and the Basque Government (38-2018-00037). M.A. (PRE_2017_1_0025) and A.Ir. (PRE_2019_1_0031) thank the Basque Government for their fellowships. MDPI http://hdl.handle.net/10810/45848 |
| spellingShingle | A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment Andonegui San Martín, Mireia native collagen chitosan scaffolds environmental assessment degradation |
| title | A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment |
| title_full | A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment |
| title_fullStr | A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment |
| title_full_unstemmed | A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment |
| title_short | A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment |
| title_sort | A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment |
| topic | native collagen chitosan scaffolds environmental assessment degradation |
| topic_facet | native collagen chitosan scaffolds environmental assessment degradation |
| url | http://hdl.handle.net/10810/45848 |