Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes

The Editorial Board of the Medicinal Chemistry section of the journal Molecules publishes here its first Editorial, which has been prepared by highlighting, in sub-editorials of about one hundred words, some selected recently published articles that may have a profound impact on drug discovery and t...

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Authors: Muñoz-Torrero López-Ibarra, Diego; Mangoni, Arduino A.; Guillou, Catherine; Collina, Simona; Vanden Eynde, Jean Jacques; Rautio, Jarkko; Keseru, György M.; Hulme, Christopher; Chibale, Kelly; Luque Garriga, F. Xavier; Karaman, Rafik; Gütschow, Michael; Liu, Hong; Ragno, Rino
Format: Article
Status:Published version
Publication date:2017
Country:España
Institution:Universidad de Barcelona
Repository:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/120834
Online Access:https://hdl.handle.net/2445/120834
Access Level:Open access
Keyword:Química farmacèutica
Pharmaceutical chemistry
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author Muñoz-Torrero López-Ibarra, Diego
author2 Mangoni, Arduino A.
Guillou, Catherine
Collina, Simona
Vanden Eynde, Jean Jacques
Rautio, Jarkko
Keseru, György M.
Hulme, Christopher
Chibale, Kelly
Luque Garriga, F. Xavier
Karaman, Rafik
Gütschow, Michael
Liu, Hong
Ragno, Rino
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author_browse Chibale, Kelly
Collina, Simona
Guillou, Catherine
Gütschow, Michael
Hulme, Christopher
Karaman, Rafik
Keseru, György M.
Liu, Hong
Luque Garriga, F. Xavier
Mangoni, Arduino A.
Muñoz-Torrero López-Ibarra, Diego
Ragno, Rino
Rautio, Jarkko
Vanden Eynde, Jean Jacques
author_facet Muñoz-Torrero López-Ibarra, Diego
Mangoni, Arduino A.
Guillou, Catherine
Collina, Simona
Vanden Eynde, Jean Jacques
Rautio, Jarkko
Keseru, György M.
Hulme, Christopher
Chibale, Kelly
Luque Garriga, F. Xavier
Karaman, Rafik
Gütschow, Michael
Liu, Hong
Ragno, Rino
author_role author
collection Dipòsit Digital de la UB
description The Editorial Board of the Medicinal Chemistry section of the journal Molecules publishes here its first Editorial, which has been prepared by highlighting, in sub-editorials of about one hundred words, some selected recently published articles that may have a profound impact on drug discovery and therapy. In particular, this editorial highlights new drug targets and mechanisms of action and new classes of drugs, as well as new therapeutic uses for known drugs or the involvement of known biological targets in new diseases. We also discuss some structural biology studies and new computational tools that may pave the way for the rational design or identification of more efficacious and safer drugs. Overall, the findings reported in these highlighted papers raise our hopes for the management of difficult-to-treat diseases that are posing a growing health threat, with new or repurposed drugs that overcome the limitations of currently applied therapies.
eu_rights_str_mv openAccess
format article
id ES_5ebc4088c2d2feff5fe3eafd4ffba049
institution Universidad de Barcelona
instname_str Universidad de Barcelona
network_acronym_str ES
network_name_str España
oai_identifier_str oai:diposit.ub.edu:2445/120834
publishDate 2017
publishDateSort 2017
publisher MDPI
publisherStr MDPI
reponame_str Dipòsit Digital de la UB
spelling Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes Muñoz-Torrero López-Ibarra, Diego Mangoni, Arduino A. Guillou, Catherine Collina, Simona Vanden Eynde, Jean Jacques Rautio, Jarkko Keseru, György M. Hulme, Christopher Chibale, Kelly Luque Garriga, F. Xavier Karaman, Rafik Gütschow, Michael Liu, Hong Ragno, Rino Química farmacèutica Pharmaceutical chemistry The Editorial Board of the Medicinal Chemistry section of the journal Molecules publishes here its first Editorial, which has been prepared by highlighting, in sub-editorials of about one hundred words, some selected recently published articles that may have a profound impact on drug discovery and therapy. In particular, this editorial highlights new drug targets and mechanisms of action and new classes of drugs, as well as new therapeutic uses for known drugs or the involvement of known biological targets in new diseases. We also discuss some structural biology studies and new computational tools that may pave the way for the rational design or identification of more efficacious and safer drugs. Overall, the findings reported in these highlighted papers raise our hopes for the management of difficult-to-treat diseases that are posing a growing health threat, with new or repurposed drugs that overcome the limitations of currently applied therapies. MDPI https://hdl.handle.net/2445/120834
spellingShingle Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
Muñoz-Torrero López-Ibarra, Diego
Química farmacèutica
Pharmaceutical chemistry
status_str publishedVersion
title Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title_full Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title_fullStr Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title_full_unstemmed Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title_short Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title_sort Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
topic Química farmacèutica
Pharmaceutical chemistry
topic_facet Química farmacèutica
Pharmaceutical chemistry
url https://hdl.handle.net/2445/120834