Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study

BackgroundHealthcare-associated infections (HAIs) are common and increase morbidity, mortality, and healthcare costs. Their control continues to be an unresolved issue worldwide. HAIs epidemiology shows sex/gender differences. Thus the lack of consideration of sex/gender in Cochrane reviews will lim...

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Authors: Lopez-Alcalde, J; Stallings, E; Nunes, SC; Chavez, AF; Daheron, M; Cosp, XB; Zamora, J
Format: Article
Status:Published version
Publication date:2019
Country:España
Institution:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repository:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p2925
Online Access:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2925
http://ddd.uab.cat/record/226396
Access Level:Open access
Keyword:Systematic reviews
Data extraction
Sex
Gender
gender
Equity
Cochrane
Gender bias
Healthcare-associated infection
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author Lopez-Alcalde, J
author2 Stallings, E
Nunes, SC
Chavez, AF
Daheron, M
Cosp, XB
Zamora, J
author2_role author
author
author
author
author
author
author_browse Chavez, AF
Cosp, XB
Daheron, M
Lopez-Alcalde, J
Nunes, SC
Stallings, E
Zamora, J
author_facet Lopez-Alcalde, J
Stallings, E
Nunes, SC
Chavez, AF
Daheron, M
Cosp, XB
Zamora, J
author_role author
collection r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
description BackgroundHealthcare-associated infections (HAIs) are common and increase morbidity, mortality, and healthcare costs. Their control continues to be an unresolved issue worldwide. HAIs epidemiology shows sex/gender differences. Thus the lack of consideration of sex/gender in Cochrane reviews will limit their applicability and capacity to support informed decisions. This study aims to describe the extent to which Cochrane reviews of interventions for preventing HAIs consider sex and gender.MethodsMethodology study appraising Cochrane reviews of interventions to prevent HAIs. Search methods: Cochrane Database of Systematic Reviews from 1995 (launch of the journal) to 31 December 2016. Two authors independently extracted data with EPPI-Reviewer 4 software, and independently appraised the sex/gender content of the reviews with the Sex and Gender Appraisal Tool for Systematic Reviews (SGAT-SR).ResultsThis study included 113 reviews assessing the effects of interventions for preventing HAIs. 100 reviews (88%) used at least one sex or gender-related term. The terminology used was heterogeneous, being sex the term used in more reviews (51%). No review defined neither sex nor gender. Thus we could not assess the definitions provided. Consideration of sex and gender was practically absent in the included reviews; in fact, no review met all the applicable items of the SGAT-SR, and 51 reviews (50%) fulfilled no item. No review provided a complete description of the sex and the gender of the samples of the included studies. Only ten reviews (10%) planned to perform sex- and gender-based analysis and only three (3%) could complete the analysis. The method chosen was always the subgroup analysis based on sex (one review) or gender (two reviews). Three reviews (3%) considered sex or gender-related findings in the conclusions.ConclusionConsideration of sex and gender in Cochrane reviews of interventions for preventing HAIs was practically absent. This lack of attention to sex and gender reduces the quality of Cochrane reviews, and their applicability for all people: women and men, boys and girls, and people of diverse gender identities. Cochrane should attempt to address the shortfalls detected.
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institution Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
instname_str Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
network_acronym_str ES
network_name_str España
oai_identifier_str oai:iibsantpau.fundanetsuite.com:p2925
publishDate 2019
publishDateSort 2019
publisher BMC
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reponame_str r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
spelling Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study Lopez-Alcalde, J Stallings, E Nunes, SC Chavez, AF Daheron, M Cosp, XB Zamora, J Systematic reviews Data extraction Sex Gender gender Equity Cochrane Gender bias Healthcare-associated infection BackgroundHealthcare-associated infections (HAIs) are common and increase morbidity, mortality, and healthcare costs. Their control continues to be an unresolved issue worldwide. HAIs epidemiology shows sex/gender differences. Thus the lack of consideration of sex/gender in Cochrane reviews will limit their applicability and capacity to support informed decisions. This study aims to describe the extent to which Cochrane reviews of interventions for preventing HAIs consider sex and gender.MethodsMethodology study appraising Cochrane reviews of interventions to prevent HAIs. Search methods: Cochrane Database of Systematic Reviews from 1995 (launch of the journal) to 31 December 2016. Two authors independently extracted data with EPPI-Reviewer 4 software, and independently appraised the sex/gender content of the reviews with the Sex and Gender Appraisal Tool for Systematic Reviews (SGAT-SR).ResultsThis study included 113 reviews assessing the effects of interventions for preventing HAIs. 100 reviews (88%) used at least one sex or gender-related term. The terminology used was heterogeneous, being sex the term used in more reviews (51%). No review defined neither sex nor gender. Thus we could not assess the definitions provided. Consideration of sex and gender was practically absent in the included reviews; in fact, no review met all the applicable items of the SGAT-SR, and 51 reviews (50%) fulfilled no item. No review provided a complete description of the sex and the gender of the samples of the included studies. Only ten reviews (10%) planned to perform sex- and gender-based analysis and only three (3%) could complete the analysis. The method chosen was always the subgroup analysis based on sex (one review) or gender (two reviews). Three reviews (3%) considered sex or gender-related findings in the conclusions.ConclusionConsideration of sex and gender in Cochrane reviews of interventions for preventing HAIs was practically absent. This lack of attention to sex and gender reduces the quality of Cochrane reviews, and their applicability for all people: women and men, boys and girls, and people of diverse gender identities. Cochrane should attempt to address the shortfalls detected. BMC https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2925 http://ddd.uab.cat/record/226396
spellingShingle Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
Lopez-Alcalde, J
Systematic reviews
Data extraction
Sex
Gender
gender
Equity
Cochrane
Gender bias
Healthcare-associated infection
status_str publishedVersion
title Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_full Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_fullStr Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_full_unstemmed Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_short Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_sort Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
topic Systematic reviews
Data extraction
Sex
Gender
gender
Equity
Cochrane
Gender bias
Healthcare-associated infection
topic_facet Systematic reviews
Data extraction
Sex
Gender
gender
Equity
Cochrane
Gender bias
Healthcare-associated infection
url https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2925
http://ddd.uab.cat/record/226396