Identifying the underlying genetic drivers of the heritability of breast cancer prognosis remains elusive. We adapt a network-based approach to handle underpowered complex datasets to provide new insights into the potential function of germline variants in breast cancer prognosis. This network-based...
Detalhes bibliográficos
| Autores: |
Escala-Garcia, Maria;
Abraham, Jean;
Andrulis, Irene L;
Anton-Culver, Hoda;
Arndt, Volker;
Ashworth, Alan;
Auer, Paul L;
Auvinen, Päivi;
Beckmann, Matthias W;
Beesley, Jonathan;
Behrens, Sabine;
Benitez, Javier;
Bermisheva, Marina;
Blomqvist, Carl;
Blot, William;
Bogdanova, Natalia V;
Bojesen, Stig E;
Bolla, Manjeet K;
Børresen-Dale, Anne-Lise;
Brauch, Hiltrud;
Brenner, Hermann;
Brucker, Sara Y;
Burwinkel, Barbara;
Caldas, Carlos;
Canzian, Federico;
Chang-Claude, Jenny;
Chanock, Stephen J;
Chin, Suet-Feung;
Clarke, Christine L;
Couch, Fergus J;
Cox, Angela;
Cross, Simon S;
Czene, Kamila;
Daly, Mary B;
Dennis, Joe;
Devilee, Peter;
Dunn, Janet A;
Dunning, Alison M;
Dwek, Miriam;
Earl, Helena M;
Eccles, Diana M;
Eliassen, A Heather;
Ellberg, Carolina;
Evans, D Gareth;
Fasching, Peter A;
Figueroa, Jonine;
Flyger, Henrik;
Gago-Dominguez, Manuela;
Gapstur, Susan M;
García-Closas, Montserrat;
García-Sáenz, José A;
Gaudet, Mia M;
George, Angela;
Giles, Graham G;
Goldgar, David E;
González-Neira, Anna;
Grip, Mervi;
Guénel, Pascal;
Guo, Qi;
Haiman, Christopher A;
Håkansson, Niclas;
Hamann, Ute;
Harrington, Patricia A;
Hiller, Louise;
Hooning, Maartje J;
Hopper, John L;
Howell, Anthony;
Huang, Chiun-Sheng;
Huang, Guanmengqian;
Hunter, David J;
Jakubowska, Anna;
John, Esther M;
Kaaks, Rudolf;
Kapoor, Pooja Middha;
Keeman, Renske;
Kitahara, Cari M;
Kraft, Peter;
Lambrechts, Diether;
Le Marchand, Loic;
Lejbkowicz, Flavio;
Lindblom, Annika;
Lubiński, Jan;
Mannermaa, Arto;
Manoochehri, Mehdi;
Manoukian, Siranoush;
Margolin, Sara;
Martinez, Maria Elena;
Maurer, Tabea;
Mavroudis, Dimitrios;
Meindl, Alfons;
Milne, Roger L;
Mulligan, Anna Marie;
Neuhausen, Susan L;
Nevanlinna, Heli;
Newman, William G;
Olshan, Andrew F;
Olson, Janet E;
Olsson, Håkan;
Orr, Nick;
Peterlongo, Paolo;
Petridis, Christos;
Prentice, Ross L;
Presneau, Nadege;
Punie, Kevin;
Ramachandran, Dhanya;
Rennert, Gad;
Romero, Atocha;
Sachchithananthan, Mythily;
Saloustros, Emmanouil;
Sawyer, Elinor J;
Schmutzler, Rita K;
Schwentner, Lukas;
Scott, Christopher;
Simard, Jacques;
Sohn, Christof;
Southey, Melissa C;
Swerdlow, Anthony J;
Tamimi, Rulla M;
Tapper, William J;
Teixeira, Manuel R;
Terry, Mary Beth;
Thorne, Heather;
Tollenaar, Rob A E M;
Tomlinson, Ian;
Troester, Melissa A;
Truong, Thérèse;
Turnbull, Clare;
Vachon, Celine M;
van der Kolk, Lizet E;
Wang, Qin;
Winqvist, Robert;
Wolk, Alicja;
Yang, Xiaohong R;
Ziogas, Argyrios;
Pharoah, Paul D P;
Hall, Per;
Wessels, Lodewyk F A;
Chenevix-Trench, Georgia;
Bader, Gary D;
Dörk, Thilo;
Easton, Douglas F;
Canisius, Sander;
Schmidt, Marjanka K;
Gonzalez Neira, Anna;
Andrulis, Irene L.;
Auer, Paul L.;
Beckmann, Matthias W.;
Bogdanova, Natalia V.;
Bojesen, Stig E.;
Bolla, Manjeet K.;
Brucker, Sara Y.;
Chanock, Stephen J.;
Clarke, Christine L.;
Couch, Fergus J.;
Cross, Simon S.;
Daly, Mary B.;
Dunn, Janet A.;
Dunning, Alison M.;
Earl, Helena M.;
Eccles, Diana M.;
Eliassen, A. Heather;
Evans, D. Gareth;
Fasching, Peter A.;
Gapstur, Susan M.;
García-Sáenz, José A.;
Gaudet, Mia M.;
Giles, Graham G.;
Goldgar, David E.;
Haiman, Christopher A.;
Harrington, Patricia A.;
Hooning, Maartje J.;
Hopper, John L.;
Hunter, David J.;
John, Esther M.;
Kitahara, Cari M.;
Koppert, Linetta B;
Kristensen, Vessela N;
Milne, Roger L.;
Neuhausen, Susan L.;
Newman, William G.;
Olshan, Andrew F.;
Olson, Janet E.;
Prentice, Ross L.;
Sawyer, Elinor J.;
Schmutzler, Rita K.;
Southey, Melissa C.;
Swerdlow, Anthony J.;
Tamimi, Rulla M.;
Tapper, William J.;
Tollenaar, Rob A. E. M.;
Troester, Melissa A.;
Vachon, Celine M.;
van der Kolk, Lizet E.;
Yang, Xiaohong R.;
Pharoah, Paul D. P.;
Wessels, Lodewyk F. A.;
Bader, Gary D.;
Easton, Douglas F.;
Schmidt, Marjanka K. |
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| Tipo de documento: | Artigo
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| Data de publicação: | 2020 |
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| País: | España |
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| Recursos: | Instituto de Salud Carlos III (ISCIII) |
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| Repositório: | Repisalud |
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| Idioma: | Inglês |
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| OAI Identifier: | oai:repisalud.isciii.es:20.500.12105/12181 |
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| Acesso em linha: | http://hdl.handle.net/20.500.12105/12181
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| Nível de acesso: | Acesso aberto |
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| Palavra-chave: | Genetic Variation
Genome-Wide Association Study
Germ Cells
Apoptosis
Breast Neoplasms
Circadian Clocks
Computational Biology
Female
GTP-Binding Protein alpha Subunits
GTP-Binding Protein alpha Subunits, Gq-G11
Gene Regulatory Networks
Genotype
Humans
Prognosis
Receptors, Estrogen
Signal Transduction |
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