Determination of the Optimal Cutoff Point for the ChemSex Inventory (CSI) to Assess Chemsex-Related Mental Health Risk in Men Who Have Sex with Men

Background Chemsex poses growing psychological and behavioural risks among men who have sex with men (MSM). Although the Chemsex Inventory (CSI) was developed to assess these risks, clinical cutoff points distinguishing recreational use from pathological patterns remain undefined. This study aimed t...

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Authors: Del Pozo-Herce, P; Martínez-Sabater, A; Chover-Sierra, EE; Czapla, M; Hernado, BS; Navas-Echazarreta, N; Juárez-Vela, R
Format: Article
Status:Published version
Publication date:2026
Country:España
Institution:INCLIVA
Repository:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:dnet:incliva_____::8586d112e456d977cbda184694913ec7
Online Access:https://incliva.portalinvestigacion.com/publicaciones/20814
Access Level:Open access
Keyword:Chemsex
Cutoff scores
Psychometrics
Mental health
Men who have sex with men
Statistical Analysis
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author Del Pozo-Herce, P
author2 Martínez-Sabater, A
Chover-Sierra, EE
Czapla, M
Hernado, BS
Navas-Echazarreta, N
Juárez-Vela, R
author2_role author
author
author
author
author
author
author_browse Chover-Sierra, EE
Czapla, M
Del Pozo-Herce, P
Hernado, BS
Juárez-Vela, R
Martínez-Sabater, A
Navas-Echazarreta, N
author_facet Del Pozo-Herce, P
Martínez-Sabater, A
Chover-Sierra, EE
Czapla, M
Hernado, BS
Navas-Echazarreta, N
Juárez-Vela, R
author_role author
collection r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
description Background Chemsex poses growing psychological and behavioural risks among men who have sex with men (MSM). Although the Chemsex Inventory (CSI) was developed to assess these risks, clinical cutoff points distinguishing recreational use from pathological patterns remain undefined. This study aimed to determine optimal CSI cutoff points to identify profiles of increased psychological and behavioral vulnerability associated with chemsex. Methods A cross-sectional study was conducted in Spain between January and April 2023 with 563 MSM who reported chemsex use within the previous 12 months. Psychometric analyses included principal component analysis (PCA) and confirmatory factor analysis (CFA) of a second-order model with four dimensions: emotional instability, risk of psychosis, altered body perception, and suicide risk. Cutoff points were determined using the percentile-based P-score method. Results The CSI showed excellent internal reliability (Cronbach's alpha = 0.88; omega = 0.88) and strong factorial validity (CFI = 0.985, TLI = 0.984, RMSEA = 0.05). The second-order model fit significantly better than the first-order alternative (chi & sup2;diff = 8.14; p = 0.017). High-risk cutoffs were: emotional instability >= 78.3, psychosis >= 51.4, body-perception disturbance >= 95.0, suicide risk >= 75.0, and global >= 66.4. About 5% of participants exceeded these thresholds, indicating elevated psychological vulnerability. Conclusions CSI cutoff points provide a reliable and sensitive tool for early detection of mental-health risks related to chemsex. Policy Implications Incorporating the CSI into sexual-health, primary-care, and mental-health services may enhance early detection of at-risk individuals and support evidence-based prevention and harm-reduction strategies.
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spelling Determination of the Optimal Cutoff Point for the ChemSex Inventory (CSI) to Assess Chemsex-Related Mental Health Risk in Men Who Have Sex with Men Del Pozo-Herce, P Martínez-Sabater, A Chover-Sierra, EE Czapla, M Hernado, BS Navas-Echazarreta, N Juárez-Vela, R Chemsex Cutoff scores Psychometrics Mental health Men who have sex with men Statistical Analysis Background Chemsex poses growing psychological and behavioural risks among men who have sex with men (MSM). Although the Chemsex Inventory (CSI) was developed to assess these risks, clinical cutoff points distinguishing recreational use from pathological patterns remain undefined. This study aimed to determine optimal CSI cutoff points to identify profiles of increased psychological and behavioral vulnerability associated with chemsex. Methods A cross-sectional study was conducted in Spain between January and April 2023 with 563 MSM who reported chemsex use within the previous 12 months. Psychometric analyses included principal component analysis (PCA) and confirmatory factor analysis (CFA) of a second-order model with four dimensions: emotional instability, risk of psychosis, altered body perception, and suicide risk. Cutoff points were determined using the percentile-based P-score method. Results The CSI showed excellent internal reliability (Cronbach's alpha = 0.88; omega = 0.88) and strong factorial validity (CFI = 0.985, TLI = 0.984, RMSEA = 0.05). The second-order model fit significantly better than the first-order alternative (chi & sup2;diff = 8.14; p = 0.017). High-risk cutoffs were: emotional instability >= 78.3, psychosis >= 51.4, body-perception disturbance >= 95.0, suicide risk >= 75.0, and global >= 66.4. About 5% of participants exceeded these thresholds, indicating elevated psychological vulnerability. Conclusions CSI cutoff points provide a reliable and sensitive tool for early detection of mental-health risks related to chemsex. Policy Implications Incorporating the CSI into sexual-health, primary-care, and mental-health services may enhance early detection of at-risk individuals and support evidence-based prevention and harm-reduction strategies. SPRINGER https://incliva.portalinvestigacion.com/publicaciones/20814
spellingShingle Determination of the Optimal Cutoff Point for the ChemSex Inventory (CSI) to Assess Chemsex-Related Mental Health Risk in Men Who Have Sex with Men
Del Pozo-Herce, P
Chemsex
Cutoff scores
Psychometrics
Mental health
Men who have sex with men
Statistical Analysis
status_str publishedVersion
title Determination of the Optimal Cutoff Point for the ChemSex Inventory (CSI) to Assess Chemsex-Related Mental Health Risk in Men Who Have Sex with Men
title_full Determination of the Optimal Cutoff Point for the ChemSex Inventory (CSI) to Assess Chemsex-Related Mental Health Risk in Men Who Have Sex with Men
title_fullStr Determination of the Optimal Cutoff Point for the ChemSex Inventory (CSI) to Assess Chemsex-Related Mental Health Risk in Men Who Have Sex with Men
title_full_unstemmed Determination of the Optimal Cutoff Point for the ChemSex Inventory (CSI) to Assess Chemsex-Related Mental Health Risk in Men Who Have Sex with Men
title_short Determination of the Optimal Cutoff Point for the ChemSex Inventory (CSI) to Assess Chemsex-Related Mental Health Risk in Men Who Have Sex with Men
title_sort Determination of the Optimal Cutoff Point for the ChemSex Inventory (CSI) to Assess Chemsex-Related Mental Health Risk in Men Who Have Sex with Men
topic Chemsex
Cutoff scores
Psychometrics
Mental health
Men who have sex with men
Statistical Analysis
topic_facet Chemsex
Cutoff scores
Psychometrics
Mental health
Men who have sex with men
Statistical Analysis
url https://incliva.portalinvestigacion.com/publicaciones/20814