Comparative Study of Methods for Cycle Length Estimation in Fractionated Electrograms of Atrial Fibrillation
[EN] Atrial cycle length (CL) is an important feature for the analysis of electrogram (EGM) characteristics acquired during catheter ablation (CA) of atrial fibrillation (AF), the commonest cardiac arrhythmia. Nevertheless, a robust ACL estimator requires the precise detection of local activation wa...
| Authors: | ; ; ; ; ; |
|---|---|
| Format: | Article |
| Publication date: | 2022 |
| Country: | España |
| Institution: | Universitat Politècnica de València (UPV) |
| Repository: | RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia |
| Language: | English |
| OAI Identifier: | oai:riunet.upv.es:10251/194781 |
| Online Access: | https://riunet.upv.es/handle/10251/194781 |
| Access Level: | Open access |
| Keyword: | Atrial fibrillation Electrogram Complex fractionated atrial electrograms Local activation waves Detection Invasive recordings Cycle length Comparison TECNOLOGIA ELECTRONICA |
| _version_ | 1878732736347242496 |
|---|---|
| author | Osorio, Diego |
| author2 | Vraka, Aikaterini Moreno-Arribas, José Bertomeu-González, Vicente Alcaraz, Raúl Rieta, J J|||0000-0002-3364-6380 |
| author2_role | author author author author author |
| author_browse | Alcaraz, Raúl Bertomeu-González, Vicente Moreno-Arribas, José Osorio, Diego Rieta, J J|||0000-0002-3364-6380 Vraka, Aikaterini |
| author_facet | Osorio, Diego Vraka, Aikaterini Moreno-Arribas, José Bertomeu-González, Vicente Alcaraz, Raúl Rieta, J J|||0000-0002-3364-6380 |
| author_role | author |
| collection | RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia |
| description | [EN] Atrial cycle length (CL) is an important feature for the analysis of electrogram (EGM) characteristics acquired during catheter ablation (CA) of atrial fibrillation (AF), the commonest cardiac arrhythmia. Nevertheless, a robust ACL estimator requires the precise detection of local activation waves (LAWs), which still remains a challenge. This work aims to compare the performance in (CL) estimation, especially under fractionated EGMs, of three different LAW detection methods relying on different operation strategies. The methods are based on the hyperbolic tangent (HT) function, an adaptive amplitude threshold (AAT) and a (CL) iteration (ACLI), respectively. For each method, LAW detection has been assessed with respect to manual annotations made by two experts and performance has been estimated by confusion matrix and mean and individual (CL) error calculation by EGM types of fractionation. The influence of EGM length on the individual (CL) error has been additionally considered. For the HT method, accuracy, sensitivity and precision were 92.77-100%, while for the AAT and ACLI methods they were 78.89-99.91% for all EGM types. The CL error on the HT method was lower than AAT and ACLI methods (up to 12 ms versus up to 20 ms), with the difference being more prominent in complex EGMs. The HT method also showed the lowest dependency on EGM length, presenting the lowest and least variable error values. Therefore, the HT method achieves higher performance in (CL) estimation in comparison with previous LAW detection techniques. The high robustness and precision demonstrated by this method suggest its implementation on CA mapping devices for a more successful location of ablation targets and improved results during CA procedures. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_48bc92bfe02fee2c45c9f00a36f12eb7 |
| institution | Universitat Politècnica de València (UPV) |
| instname_str | Universitat Politècnica de València (UPV) |
| language | eng |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:riunet.upv.es:10251/194781 |
| publishDate | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI AG |
| publisherStr | MDPI AG |
| reponame_str | RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia |
| spelling | Comparative Study of Methods for Cycle Length Estimation in Fractionated Electrograms of Atrial Fibrillation Osorio, Diego Vraka, Aikaterini Moreno-Arribas, José Bertomeu-González, Vicente Alcaraz, Raúl Rieta, J J|||0000-0002-3364-6380 Atrial fibrillation Electrogram Complex fractionated atrial electrograms Local activation waves Detection Invasive recordings Cycle length Comparison TECNOLOGIA ELECTRONICA [EN] Atrial cycle length (CL) is an important feature for the analysis of electrogram (EGM) characteristics acquired during catheter ablation (CA) of atrial fibrillation (AF), the commonest cardiac arrhythmia. Nevertheless, a robust ACL estimator requires the precise detection of local activation waves (LAWs), which still remains a challenge. This work aims to compare the performance in (CL) estimation, especially under fractionated EGMs, of three different LAW detection methods relying on different operation strategies. The methods are based on the hyperbolic tangent (HT) function, an adaptive amplitude threshold (AAT) and a (CL) iteration (ACLI), respectively. For each method, LAW detection has been assessed with respect to manual annotations made by two experts and performance has been estimated by confusion matrix and mean and individual (CL) error calculation by EGM types of fractionation. The influence of EGM length on the individual (CL) error has been additionally considered. For the HT method, accuracy, sensitivity and precision were 92.77-100%, while for the AAT and ACLI methods they were 78.89-99.91% for all EGM types. The CL error on the HT method was lower than AAT and ACLI methods (up to 12 ms versus up to 20 ms), with the difference being more prominent in complex EGMs. The HT method also showed the lowest dependency on EGM length, presenting the lowest and least variable error values. Therefore, the HT method achieves higher performance in (CL) estimation in comparison with previous LAW detection techniques. The high robustness and precision demonstrated by this method suggest its implementation on CA mapping devices for a more successful location of ablation targets and improved results during CA procedures. This research has received financial support from public grants PID2021-123804OB-I00 and PID2021-00X128525-IV0 of the Spanish Government with DOI 10.13039/501100011033 jointly with the European Regional Development Fund (EU), and regional grants SBPLY/17/180501/000411 from Junta de Comunidades de Castilla-La Mancha and AICO/2021/286 from Generalitat Valenciana. MDPI AG https://riunet.upv.es/handle/10251/194781 |
| spellingShingle | Comparative Study of Methods for Cycle Length Estimation in Fractionated Electrograms of Atrial Fibrillation Osorio, Diego Atrial fibrillation Electrogram Complex fractionated atrial electrograms Local activation waves Detection Invasive recordings Cycle length Comparison TECNOLOGIA ELECTRONICA |
| title | Comparative Study of Methods for Cycle Length Estimation in Fractionated Electrograms of Atrial Fibrillation |
| title_full | Comparative Study of Methods for Cycle Length Estimation in Fractionated Electrograms of Atrial Fibrillation |
| title_fullStr | Comparative Study of Methods for Cycle Length Estimation in Fractionated Electrograms of Atrial Fibrillation |
| title_full_unstemmed | Comparative Study of Methods for Cycle Length Estimation in Fractionated Electrograms of Atrial Fibrillation |
| title_short | Comparative Study of Methods for Cycle Length Estimation in Fractionated Electrograms of Atrial Fibrillation |
| title_sort | Comparative Study of Methods for Cycle Length Estimation in Fractionated Electrograms of Atrial Fibrillation |
| topic | Atrial fibrillation Electrogram Complex fractionated atrial electrograms Local activation waves Detection Invasive recordings Cycle length Comparison TECNOLOGIA ELECTRONICA |
| topic_facet | Atrial fibrillation Electrogram Complex fractionated atrial electrograms Local activation waves Detection Invasive recordings Cycle length Comparison TECNOLOGIA ELECTRONICA |
| url | https://riunet.upv.es/handle/10251/194781 |