Mathematical modelling of respiratory syncytial virus (RSV): vaccination strategies and budget applications

We propose an age-structured mathematical model for respiratory syncytial virus in which children aged <1 year are especially considered. Real data on hospitalized children in the Spanish region of Valencia were used in order to determine some seasonal parameters of the model. Weekly predictions of...

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Bibliographic Details
Authors: Acedo L; Díez-Domingo J; Moraño JA; Villanueva RJ
Format: Article
Status:Published version
Publication date:2010
Country:España
Institution:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repository:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p3415
Online Access:https://fisabio.portalinvestigacion.com/publicaciones/3415
Access Level:Open access
Keyword:Cost-effectiveness study
respiratory syncytial virus
vaccine policy development
Description
Summary:We propose an age-structured mathematical model for respiratory syncytial virus in which children aged <1 year are especially considered. Real data on hospitalized children in the Spanish region of Valencia were used in order to determine some seasonal parameters of the model. Weekly predictions of the number of children aged <1 year that will be hospitalized in the following years in Valencia are presented using this model. Results are applied to estimate the regional cost of paediatric hospitalizations and to perform a cost-effectiveness analysis of possible vaccination strategies.