SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV
People living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH is vital. We assessed SARS-CoV-2 vaccination cover...
| Autores: | ; ; ; ; ; ; ; ; ; ; ; ; ; |
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| Tipo de documento: | Artículo |
| Estado: | Published version |
| Fecha de publicación: | 2022 |
| País: | España |
| Institución: | Institut d'Investigació i Innovació Parc Taulí (I3PT) |
| Repositorio: | r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí |
| OAI Identifier: | oai:i3pt.fundanetsuite.com:p1270 |
| Acceso en línea: | https://i3pt.portalinvestigacion.com/publicaciones/1270 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137344633&doi=10.3390%2fmicroorganisms10081666&partnerID=40&md5=efb2cdee7678d0d31e8217c59e6528bf |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | HIV severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus disease 2019 (COVID-19) vaccination vaccine effectiveness |
| _version_ | 1878731751715504128 |
|---|---|
| author | Nomah, DK |
| author2 | Llibre, JM Diaz, Y Moreno, S Aceiton, J Bruguera, A Gutierrez-Macia, M Imaz, A Suanzes, P Navarro, G Orti, A Miro, JM Casabona, J Reyes-Uruena, J |
| author2_role | author author author author author author author author author author author author author |
| author_browse | Aceiton, J Bruguera, A Casabona, J Diaz, Y Gutierrez-Macia, M Imaz, A Llibre, JM Miro, JM Moreno, S Navarro, G Nomah, DK Orti, A Reyes-Uruena, J Suanzes, P |
| author_facet | Nomah, DK Llibre, JM Diaz, Y Moreno, S Aceiton, J Bruguera, A Gutierrez-Macia, M Imaz, A Suanzes, P Navarro, G Orti, A Miro, JM Casabona, J Reyes-Uruena, J |
| author_role | author |
| collection | r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí |
| description | People living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH is vital. We assessed SARS-CoV-2 vaccination coverage and factors associated with under-vaccination among PLWH in Catalonia, Spain. As of 11.12.2021, 9945/14942 PLWH (66.6%) had received >= 1 dose of a SARS-CoV-2 vaccine. Non-Spanish origin (adjusted odds ratio (aOR) 0.64, 95% CI 0.59-0.70), CD4 count of 200-349 cells/mu L (aOR 0.74, 95% CI 0.64-0.86) or 350-499 cells/mu L (aOR 0.79, 95% CI 0.70-0.88), detectable plasma HIV-RNA (aOR 0.61 95% CI 0.53-0.70), and previous SARS-CoV-2 diagnosis (aOR 0.58 95% CI 0.51-0.65) were associated with under-vaccination. SARS-CoV-2 diagnosis (437 [9.5%] vs. 323 [3.5%], p < 0.001), associated hospitalisations (10 [2.3%] vs. 0 [0%], p < 0.001), intensive care unit admissions (6 [1.4%] vs. 0 [0%], p < 0.001), and deaths (10 [2.3%] vs. 0 [0%], p < 0.001) were higher among unvaccinated PLWH. Vaccination coverage was lower among PLWH with a CD4 count >200 cells/mu L, detectable plasma HIV-RNA, previous SARS-CoV-2 diagnosis, and migrants. SARS-CoV-2 diagnosis, associated hospitalisations, and deaths among PLWH were lower among the vaccinated compared with the unvaccinated. SARS-CoV-2 vaccination prioritisation has not completely reached vulnerable PLWH with poorer prognosis. This information can be used to inform public health strategies. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_35ca4100370bc706207a9a96f986f472 |
| institution | Institut d'Investigació i Innovació Parc Taulí (I3PT) |
| instname_str | Institut d'Investigació i Innovació Parc Taulí (I3PT) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:i3pt.fundanetsuite.com:p1270 |
| publishDate | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI |
| publisherStr | MDPI |
| reponame_str | r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí |
| spelling | SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV Nomah, DK Llibre, JM Diaz, Y Moreno, S Aceiton, J Bruguera, A Gutierrez-Macia, M Imaz, A Suanzes, P Navarro, G Orti, A Miro, JM Casabona, J Reyes-Uruena, J HIV severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus disease 2019 (COVID-19) vaccination vaccine effectiveness People living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH is vital. We assessed SARS-CoV-2 vaccination coverage and factors associated with under-vaccination among PLWH in Catalonia, Spain. As of 11.12.2021, 9945/14942 PLWH (66.6%) had received >= 1 dose of a SARS-CoV-2 vaccine. Non-Spanish origin (adjusted odds ratio (aOR) 0.64, 95% CI 0.59-0.70), CD4 count of 200-349 cells/mu L (aOR 0.74, 95% CI 0.64-0.86) or 350-499 cells/mu L (aOR 0.79, 95% CI 0.70-0.88), detectable plasma HIV-RNA (aOR 0.61 95% CI 0.53-0.70), and previous SARS-CoV-2 diagnosis (aOR 0.58 95% CI 0.51-0.65) were associated with under-vaccination. SARS-CoV-2 diagnosis (437 [9.5%] vs. 323 [3.5%], p < 0.001), associated hospitalisations (10 [2.3%] vs. 0 [0%], p < 0.001), intensive care unit admissions (6 [1.4%] vs. 0 [0%], p < 0.001), and deaths (10 [2.3%] vs. 0 [0%], p < 0.001) were higher among unvaccinated PLWH. Vaccination coverage was lower among PLWH with a CD4 count >200 cells/mu L, detectable plasma HIV-RNA, previous SARS-CoV-2 diagnosis, and migrants. SARS-CoV-2 diagnosis, associated hospitalisations, and deaths among PLWH were lower among the vaccinated compared with the unvaccinated. SARS-CoV-2 vaccination prioritisation has not completely reached vulnerable PLWH with poorer prognosis. This information can be used to inform public health strategies. MDPI https://i3pt.portalinvestigacion.com/publicaciones/1270 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137344633&doi=10.3390%2fmicroorganisms10081666&partnerID=40&md5=efb2cdee7678d0d31e8217c59e6528bf |
| spellingShingle | SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV Nomah, DK HIV severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus disease 2019 (COVID-19) vaccination vaccine effectiveness |
| status_str | publishedVersion |
| title | SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV |
| title_full | SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV |
| title_fullStr | SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV |
| title_full_unstemmed | SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV |
| title_short | SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV |
| title_sort | SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV |
| topic | HIV severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus disease 2019 (COVID-19) vaccination vaccine effectiveness |
| topic_facet | HIV severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus disease 2019 (COVID-19) vaccination vaccine effectiveness |
| url | https://i3pt.portalinvestigacion.com/publicaciones/1270 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137344633&doi=10.3390%2fmicroorganisms10081666&partnerID=40&md5=efb2cdee7678d0d31e8217c59e6528bf |