Biomedical application of VIMP: screening of malignant cells in the prostate

An electrochemical method for discriminating healthy and malignant tissues in prostate biopsies using the voltammetry of immobilized particles methodology is described. The method involves the sampling with graphite bars 0.5 mm in diameter on paraffin-impregnated cross sections of prostate tissues u...

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Authors: Domenech-Carbo, A; Domenech-Casasus, C; Pontones, JL; Ramos, D
Format: Article
Status:Published version
Publication date:2020
Country:España
Institution:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repository:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p9177
Online Access:https://fisabio.portalinvestigacion.com/publicaciones/9177
Access Level:Open access
Keyword:Prostate cancer
Voltammetry of microparticles
Methylene blue
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author Domenech-Carbo, A
author2 Domenech-Casasus, C
Pontones, JL
Ramos, D
author2_role author
author
author
author_browse Domenech-Carbo, A
Domenech-Casasus, C
Pontones, JL
Ramos, D
author_facet Domenech-Carbo, A
Domenech-Casasus, C
Pontones, JL
Ramos, D
author_role author
collection r-FISABIO. Repositorio Institucional de Producción Científica
description An electrochemical method for discriminating healthy and malignant tissues in prostate biopsies using the voltammetry of immobilized particles methodology is described. The method involves the sampling with graphite bars 0.5 mm in diameter on paraffin-impregnated cross sections of prostate tissues used in ordinary cytological evaluation after local staining with methylene blue (MB). The subsequent record of the voltammetric response of sample-modified graphite electrodes displays clearly different MB-centered features for healthy and malignant regions due to the different association of the dye to the respective cells.
eu_rights_str_mv openAccess
format article
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institution Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
network_acronym_str ES
network_name_str España
oai_identifier_str oai:fisabio.fundanetsuite.com:p9177
publishDate 2020
publishDateSort 2020
publisher SPRINGER
publisherStr SPRINGER
reponame_str r-FISABIO. Repositorio Institucional de Producción Científica
spelling Biomedical application of VIMP: screening of malignant cells in the prostate Domenech-Carbo, A Domenech-Casasus, C Pontones, JL Ramos, D Prostate cancer Voltammetry of microparticles Methylene blue An electrochemical method for discriminating healthy and malignant tissues in prostate biopsies using the voltammetry of immobilized particles methodology is described. The method involves the sampling with graphite bars 0.5 mm in diameter on paraffin-impregnated cross sections of prostate tissues used in ordinary cytological evaluation after local staining with methylene blue (MB). The subsequent record of the voltammetric response of sample-modified graphite electrodes displays clearly different MB-centered features for healthy and malignant regions due to the different association of the dye to the respective cells. SPRINGER https://fisabio.portalinvestigacion.com/publicaciones/9177
spellingShingle Biomedical application of VIMP: screening of malignant cells in the prostate
Domenech-Carbo, A
Prostate cancer
Voltammetry of microparticles
Methylene blue
status_str publishedVersion
title Biomedical application of VIMP: screening of malignant cells in the prostate
title_full Biomedical application of VIMP: screening of malignant cells in the prostate
title_fullStr Biomedical application of VIMP: screening of malignant cells in the prostate
title_full_unstemmed Biomedical application of VIMP: screening of malignant cells in the prostate
title_short Biomedical application of VIMP: screening of malignant cells in the prostate
title_sort Biomedical application of VIMP: screening of malignant cells in the prostate
topic Prostate cancer
Voltammetry of microparticles
Methylene blue
topic_facet Prostate cancer
Voltammetry of microparticles
Methylene blue
url https://fisabio.portalinvestigacion.com/publicaciones/9177