Quantifying forces in cell biology
Cells exert, sense, and respond to physical forces through an astounding diversity of mechanisms. Here we review recently developed tools to quantify the forces generated by cells. We first review technologies based on sensors of known or assumed mechanical properties, and discuss their applicabilit...
| Authors: | ; ; |
|---|---|
| Format: | Article |
| Status: | Accepted version |
| Publication date: | 2017 |
| Country: | España |
| Institution: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repository: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2445/180611 |
| Online Access: | https://hdl.handle.net/2445/180611 |
| Access Level: | Open access |
| Keyword: | Cèl·lules Citosquelet Membranes cel·lulars Propietats mecàniques Cells Cytoskeleton Cell membranes Mechanical properties |
| _version_ | 1878731590786351104 |
|---|---|
| author | Roca-Cusachs Soulere, Pere |
| author2 | Conte, Vito Trepat Guixer, Xavier |
| author2_role | author author |
| author_browse | Conte, Vito Roca-Cusachs Soulere, Pere Trepat Guixer, Xavier |
| author_facet | Roca-Cusachs Soulere, Pere Conte, Vito Trepat Guixer, Xavier |
| author_role | author |
| collection | Recercat. Dipósit de la Recerca de Catalunya |
| description | Cells exert, sense, and respond to physical forces through an astounding diversity of mechanisms. Here we review recently developed tools to quantify the forces generated by cells. We first review technologies based on sensors of known or assumed mechanical properties, and discuss their applicability and limitations. We then proceed to draw an analogy between these human-made sensors and force sensing in the cell. As mechanics is increasingly revealed to play a fundamental role in cell function we envisage that tools to quantify physical forces may soon become widely applied in life-sciences laboratories. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_32ac1825f7700a0989fa426b35aef44f |
| institution | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| instname_str | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:recercat.cat:2445/180611 |
| publishDate | 2017 |
| publishDateSort | 2017 |
| publisher | Nature Publishing Group |
| publisherStr | Nature Publishing Group |
| reponame_str | Recercat. Dipósit de la Recerca de Catalunya |
| spelling | Quantifying forces in cell biology Roca-Cusachs Soulere, Pere Conte, Vito Trepat Guixer, Xavier Cèl·lules Citosquelet Membranes cel·lulars Propietats mecàniques Cells Cytoskeleton Cell membranes Mechanical properties Cells exert, sense, and respond to physical forces through an astounding diversity of mechanisms. Here we review recently developed tools to quantify the forces generated by cells. We first review technologies based on sensors of known or assumed mechanical properties, and discuss their applicability and limitations. We then proceed to draw an analogy between these human-made sensors and force sensing in the cell. As mechanics is increasingly revealed to play a fundamental role in cell function we envisage that tools to quantify physical forces may soon become widely applied in life-sciences laboratories. Nature Publishing Group https://hdl.handle.net/2445/180611 |
| spellingShingle | Quantifying forces in cell biology Roca-Cusachs Soulere, Pere Cèl·lules Citosquelet Membranes cel·lulars Propietats mecàniques Cells Cytoskeleton Cell membranes Mechanical properties |
| status_str | acceptedVersion |
| title | Quantifying forces in cell biology |
| title_full | Quantifying forces in cell biology |
| title_fullStr | Quantifying forces in cell biology |
| title_full_unstemmed | Quantifying forces in cell biology |
| title_short | Quantifying forces in cell biology |
| title_sort | Quantifying forces in cell biology |
| topic | Cèl·lules Citosquelet Membranes cel·lulars Propietats mecàniques Cells Cytoskeleton Cell membranes Mechanical properties |
| topic_facet | Cèl·lules Citosquelet Membranes cel·lulars Propietats mecàniques Cells Cytoskeleton Cell membranes Mechanical properties |
| url | https://hdl.handle.net/2445/180611 |