Performance characteristics of the whole-body discovery IQ PET/CT system
The aim of this study was to assess the physical performance of a new PET/CT system, the Discovery IQ with 5-ring detector blocks. Methods: Performance was measured using the National Electrical Manufacturers Association NU2-2012 methodology. Image quality was extended by accounting for different ac...
| Autores: | ; ; ; ; ; |
|---|---|
| Tipo de documento: | Artigo |
| Estado: | Published version |
| Data de publicação: | 2017 |
| País: | España |
| Recursos: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositório: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2445/132887 |
| Acesso em linha: | https://hdl.handle.net/2445/132887 |
| Nível de acesso: | Acesso aberto |
| Palavra-chave: | Tumors Diagnòstic per la imatge Tomografia per emissió de positrons Imatge corporal Diagnostic imaging Positron emission tomography Body image |
| _version_ | 1878730612060192769 |
|---|---|
| author | Reynés-Llompart, Gabriel |
| author2 | Gámez, Cristina Romero-Zayas, Immaculada Rodríguez Bel, Laura Vercher Conejero, José Luís Martí-Climent, Josep M. |
| author2_role | author author author author author |
| author_browse | Gámez, Cristina Martí-Climent, Josep M. Reynés-Llompart, Gabriel Rodríguez Bel, Laura Romero-Zayas, Immaculada Vercher Conejero, José Luís |
| author_facet | Reynés-Llompart, Gabriel Gámez, Cristina Romero-Zayas, Immaculada Rodríguez Bel, Laura Vercher Conejero, José Luís Martí-Climent, Josep M. |
| author_role | author |
| collection | Recercat. Dipósit de la Recerca de Catalunya |
| description | The aim of this study was to assess the physical performance of a new PET/CT system, the Discovery IQ with 5-ring detector blocks. Methods: Performance was measured using the National Electrical Manufacturers Association NU2-2012 methodology. Image quality was extended by accounting for different acquisition parameters (lesion-to-background ratios [8:1, 4:1, and 2:1] and acquisition times) and reconstruction algorithms (VUE-point HD [VPHD], VPHD with point-spread-function modeling [VPHD-S], and Q.Clear). Tomographic reconstruction was also assessed using a Jaszczak phantom. Additionally, 30 patient lesions were analyzed to account for differences in lesion volume and SUV quantification between reconstruction algorithms. Results: Spatial resolution ranged from 4.2 mm at 1 cm to 8.5 mm at 20 cm. Sensitivity measured at the center and at 10 cm was 22.8 and 20.4 kps/kBq, respectively. The noise-equivalent counting rate peak was 124 kcps at 9.1 kBq/cm3 The scatter fraction was 36.2%. The accuracy of correction for count losses and randoms was 3.9%. In the image quality test, contrast recovery for VPHD, VPHD-S, and Q.Clear ranged from 18%, 18%, and 13%, respectively (hot contrast; 10-mm sphere diameter; ratio, 2:1), to 68%, 67%, and 81%, respectively (cold contrast; 37-mm sphere diameter; ratio, 8:1). Background variability ranged from 3.4%, 3.0%, and 2.1%, respectively (ratio, 2:1), to 5.5%, 4.8%, and 3.7%, respectively (ratio, 8:1). On Q.Clear reconstruction, the decrease in the penalty term (β) increased the contrast recovery coefficients and background variability. With the Jaszczak phantom, image quality increased overall when a reconstruction algorithm modeling the point-spread function was used, and use of Q.Clear increased the signal-to-noise ratio. Lesions analyzed using VPHD-S and Q.Clear had an SUVmean of 6.5 ± 3 and 7 ± 3, respectively (P < 0.01), and an SUVmax of 11 ± 4.8 and 12 ± 4, respectively (P < 0.01). No significant difference in mean lesion volume was found between algorithms. Conclusion: Among the various Discovery bismuth germanium oxide-based PET/CT scanners, the IQ with 5-ring detector blocks has the highest overall performance, with improved sensitivity and counting rate performance. Q.Clear reconstruction improves the PET image quality, with higher recovery coefficients and lower background variability. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_1fd4f7356ab02d13c9cf3b15efc19fce |
| institution | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| instname_str | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:recercat.cat:2445/132887 |
| publishDate | 2017 |
| publishDateSort | 2017 |
| publisher | The Society of Nuclear Medicine and Molecular Imaging |
| publisherStr | The Society of Nuclear Medicine and Molecular Imaging |
| reponame_str | Recercat. Dipósit de la Recerca de Catalunya |
| spelling | Performance characteristics of the whole-body discovery IQ PET/CT system Reynés-Llompart, Gabriel Gámez, Cristina Romero-Zayas, Immaculada Rodríguez Bel, Laura Vercher Conejero, José Luís Martí-Climent, Josep M. Tumors Diagnòstic per la imatge Tomografia per emissió de positrons Imatge corporal Diagnostic imaging Positron emission tomography Body image The aim of this study was to assess the physical performance of a new PET/CT system, the Discovery IQ with 5-ring detector blocks. Methods: Performance was measured using the National Electrical Manufacturers Association NU2-2012 methodology. Image quality was extended by accounting for different acquisition parameters (lesion-to-background ratios [8:1, 4:1, and 2:1] and acquisition times) and reconstruction algorithms (VUE-point HD [VPHD], VPHD with point-spread-function modeling [VPHD-S], and Q.Clear). Tomographic reconstruction was also assessed using a Jaszczak phantom. Additionally, 30 patient lesions were analyzed to account for differences in lesion volume and SUV quantification between reconstruction algorithms. Results: Spatial resolution ranged from 4.2 mm at 1 cm to 8.5 mm at 20 cm. Sensitivity measured at the center and at 10 cm was 22.8 and 20.4 kps/kBq, respectively. The noise-equivalent counting rate peak was 124 kcps at 9.1 kBq/cm3 The scatter fraction was 36.2%. The accuracy of correction for count losses and randoms was 3.9%. In the image quality test, contrast recovery for VPHD, VPHD-S, and Q.Clear ranged from 18%, 18%, and 13%, respectively (hot contrast; 10-mm sphere diameter; ratio, 2:1), to 68%, 67%, and 81%, respectively (cold contrast; 37-mm sphere diameter; ratio, 8:1). Background variability ranged from 3.4%, 3.0%, and 2.1%, respectively (ratio, 2:1), to 5.5%, 4.8%, and 3.7%, respectively (ratio, 8:1). On Q.Clear reconstruction, the decrease in the penalty term (β) increased the contrast recovery coefficients and background variability. With the Jaszczak phantom, image quality increased overall when a reconstruction algorithm modeling the point-spread function was used, and use of Q.Clear increased the signal-to-noise ratio. Lesions analyzed using VPHD-S and Q.Clear had an SUVmean of 6.5 ± 3 and 7 ± 3, respectively (P < 0.01), and an SUVmax of 11 ± 4.8 and 12 ± 4, respectively (P < 0.01). No significant difference in mean lesion volume was found between algorithms. Conclusion: Among the various Discovery bismuth germanium oxide-based PET/CT scanners, the IQ with 5-ring detector blocks has the highest overall performance, with improved sensitivity and counting rate performance. Q.Clear reconstruction improves the PET image quality, with higher recovery coefficients and lower background variability. The Society of Nuclear Medicine and Molecular Imaging https://hdl.handle.net/2445/132887 |
| spellingShingle | Performance characteristics of the whole-body discovery IQ PET/CT system Reynés-Llompart, Gabriel Tumors Diagnòstic per la imatge Tomografia per emissió de positrons Imatge corporal Diagnostic imaging Positron emission tomography Body image |
| status_str | publishedVersion |
| title | Performance characteristics of the whole-body discovery IQ PET/CT system |
| title_full | Performance characteristics of the whole-body discovery IQ PET/CT system |
| title_fullStr | Performance characteristics of the whole-body discovery IQ PET/CT system |
| title_full_unstemmed | Performance characteristics of the whole-body discovery IQ PET/CT system |
| title_short | Performance characteristics of the whole-body discovery IQ PET/CT system |
| title_sort | Performance characteristics of the whole-body discovery IQ PET/CT system |
| topic | Tumors Diagnòstic per la imatge Tomografia per emissió de positrons Imatge corporal Diagnostic imaging Positron emission tomography Body image |
| topic_facet | Tumors Diagnòstic per la imatge Tomografia per emissió de positrons Imatge corporal Diagnostic imaging Positron emission tomography Body image |
| url | https://hdl.handle.net/2445/132887 |