Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial
BACKGROUND Patients with acute coronary syndrome (ACS) and concomitant noncoronary atherosclerosis have a high risk of major adverse cardiovascular events (MACEs) and death. The impact of lipid lowering by proprotein convertase subtilisin-kexin type 9 inhibition in such patients is undetermined. OBJ...
| Autores: | ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; |
|---|---|
| Tipo de documento: | Artículo |
| Estado: | Published version |
| Fecha de publicación: | 2019 |
| País: | España |
| Institución: | Institut d'Investigació i Innovació Parc Taulí (I3PT) |
| Repositorio: | r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí |
| OAI Identifier: | oai:i3pt.fundanetsuite.com:p2904 |
| Acceso en línea: | https://i3pt.portalinvestigacion.com/publicaciones/2904 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | acute coronary syndrome alirocumab cerebrovascular disease death major adverse cardiac events peripheral artery disease |
| _version_ | 1878730328477007872 |
|---|---|
| author | Jukema, JW |
| author2 | Szarek, M Zijlstra, LE de Silva, HA Bhatt, DL Bittner, VA Diaz, R Edelberg, JM Hanotin, C Harrington, RA Moryusef, A White, HD Zeiher, AM Schwartz, GG Steg, PG Tricoci, P Mahaffey, KW Lecorps, G Pordy, R Sasiela, WJ Drexel, H Sinnaeve, P Dilic, M Gotcheva, NN Goodman, SG Prieto, JC Yong, H Lopez-Jaramillo, P Pecin, I Reiner, Z Poulsen, SH Viigimaa, M Nieminen, MS Danchin, N Chumburidze, V Tse, HF Xavier, D Zahger, D Valgimigli, M Kim, HS Erglis, A Laucevicius, A Lopez, R Lopez, GAR Alings, M Chua, T Murin, J Fras, Z Dalby, AJ Tunon, J De Silva, HA Chiang, CE Sritara, P Guneri, S Parkhomenko, A Ray, KK Moriarty, PM Roe, MT Chaitman, B Kelsey, SF Olsson, AG Rouleau, JL Simoons, ML Alexander, K Meloni, C Rosenson, R Sijbrands, EJG Alexander, JH Armaganijan, L Bagai, A Bahit, MC Brennan, JM Clifton, S DeVore, AD Deloatch, S Dickey, S Dombrowski, K Ducrocq, G Eapen, Z Endsley, P Eppinger, A Harrison, RW Hess, CN Hlatky, MA Jordan, JD Knowles, JW Kolls, BJ Kong, DF Leonardi, S Lillis, L Maron, DJ Marcus, J Mathews, R Mehta, RH Mentz, RJ Moreira, HG Patel, CB Pereira, SB Perkins, L Povsic, TJ Puymirat, E Jones, WS Shah, BR Sherwood, MW Stringfellow, K Sujjavanich, D Toma, M Van Diepen, SFP Wilson, MD Yan, ATK Lopes, RD Trotter, C Schiavi, LB Garrido, M Alvarisqueta, AF Sassone, SA Bordonava, AP De Lima, AEA Schmidberg, JM Duronto, EA Caruso, OC Novaretto, LP Hominal, MA Montana, OR Caccavo, A Vilamajo, OAG Lorenzatti, AJ Cartasegna, LR Paterlini, GA Mackinnon, IJ Caime, GD Amuchastegui, M Salomone, R Codutti, OR Jure, HO Bono, JOE Hrabar, AD Vallejos, JA Guerrero, RAA Novoa, F Patocchi, CA Zaidman, CJ Giuliano, ME Dran, RD Vico, ML Carnero, GS Guzman, PN Allende, JCM Brasca, DFG Labarta, MHB Nani, S Blumberg, EDS Colombo, HR Liberman, A Luciardi, HL Waisman, GD Berli, MA Duran, ROG Cestari, HG Luquez, HA Giordano, JA Saavedra, SS Zapata, G Costamagna, O Llois, S Waites, JH Collins, N Soward, A Aylward, PE Hii, CLS Shaw, J Arstall, MA Horowitz, J Rogers, JF Colquhoun, D Flores, REO Roberts-Thomson, P Raffel, O Lehman, SJ Aroney, C Coverdale, SGM Garrahy, PJ Starmer, G Sader, M Carroll, PA Dick, R Zweiker, R Hoppe, U Huber, K Berger, R Weidinger, F Faes, D Hermans, K Pirenne, B Leone, A Hoffer, E Vrolix, MCM De Wolf, L Wollaert, B Castadot, M Dujardin, K Beauloye, C Vervoort, G Striekwold, H Convens, C Roosen, J Barbato, E Claeys, M Cools, F Terzic, I Barakovic, F Midzic, Z Pojskic, B Fazlibegovic, E Durak-Nalbantic, A Vulic, D Muslibegovic, A Goronja, B Reis, G Sousa, L Nicolau, JC Giorgeto, FE Silva, RP Maia, LN Rech, R Rossi, PRF Cerqueira, MJAG Duda, N Kalil, R Kormann, A Abrantes, JAM Pimentel, P Soggia, AP de Santos, MON Neuenschwander, F Bodanese, LC Michalaros, YL Eliaschewitz, FG Vidotti, MH Leaes, PE Botelho, RV Kaiser, S Manenti, ERFF Precoma, DB Jorge, JCM Silva, PGMD Silveira, JA Saporito, W Marin, JA Feitosa, GS Ritt, LEF de Souza, JA Costa, F Souza, WKSB Reis, HJL Machado, L Ayoub, JCA Todorov, GV Nikolov, FP Velcheva, ES Tzekova, ML Benov, HO Petranov, SL Tumbev, HS Shehova-Yankova, NS Markov, DT Raev, DH Mollov, MN Kichukov, KN Ilieva-Pandeva, KA Ivanova, R Mincheva, VM Lazov, PV Dimov, BI Senaratne, M Stone, J Kornder, J Pearce, S Dion, D Savard, D Pesant, Y Pandey, A Robinson, S Gosselin, G Vizel, S Hoag, G Bourgeois, R Morisset, A Sabbah, E Sussex, B Kouz, S MacDonald, P Diaz, A Michaud, N Fell, D Leung, R Vuurmans, T Lai, C Nigro, F Davies, R Nogareda, G Vijayaraghavan, R Ducas, J Lepage, S Mehta, S Cha, J Dupuis, R Fong, P Rodes-Cabau, J Fadlallah, H Cleveland, D Huynh, T Bata, I Hameed, A Pincetti, C Potthoff, S Acevedo, M Aguirre, A Vejar, M Yanez, M Araneda, G Fernandez, M Perez, L Varleta, P Florenzano, F Huidobro, L Raffo, CA Olivares, C Nahuelpan, L Montecinos, H Chen, JY Dong, YG Huang, WJ Wang, JZ Huang, SA Yao, ZH Li, X Cui, L Lin, WH Sun, YM Wang, JF Li, JP Zhang, XL Zhu, H Chen, D Huang, L Dong, SH Su, GH Xu, BA Su, X Cheng, XS Lin, JX Zong, WX Li, HM Feng, Y Xu, DL Yang, XC Ke, YN Lin, XF Zhang, Z Zheng, ZQ Luo, ZR Chen, YD Ding, CH Zheng, Y Li, XD Peng, DQ Li, Y Wei, M Liu, SW Yu, YH Qu, BM Jiang, WH Zhou, YJ Zhao, XS Yuan, ZY Guo, Y Xu, XP Shi, XB Ge, JB Fu, GS Bai, F Fang, WY Shou, XL Yang, XJ Wang, JA Sun, YX Lu, QH Zhang, RY Zhu, JH Xu, YZ Fan, ZC Li, TC Wu, C Jaramillo, N Vallejo, GS Botia, DCL Lopez, RB De Salazar, DIM Bonfanti, AJC Higuera, JD Silva, SIB Lozada, HJG Arroyo, JAC Mendoza, JLA Ruiz, RLF Jatin, FGM Herazo, AS Parada, JC Triana, MAU Strozzi, M Car, S Milicic, D Bencic, ML Pintaric, H Prvulovic, D Sikic, J Persic, V Mileta, D Stambuk, K Zdravko, B Tomulic, V Krstulovic, SM Starcevic, B Spinar, J Horak, D Stasek, J Alan, D Machova, V Linhart, A Novotny, V Kaucak, V Rokyta, R Naplava, R Coufal, Z Adamkova, V Podpera, I Zizka, J Motovska, Z Marusincova, I Svab, P Ostadal, P Heinc, P Kuchar, J Povolny, P Matuska, J Raungaard, B Clemmensen, P Bang, LE May, O Bottcher, M Hove, JD Frost, L Gislason, G Larsen, J Johansen, PB Hald, F Jeppesen, J Nielsen, T Kristensen, KS Walichiewicz, PM Lomholdt, JD Klausen, IC Nielsen, PK Davidsen, F Videbaek, L Soots, M Vahula, V Hedman, A Soopold, U Martsin, K Kristjan, A Taskinen, MR Porthan, K Airaksinen, JK Juonala, M Kiviniemi, T Vikman, S Posio, P Taurio, J Huikuri, H Kaikkonen, K Coste, P Ferrari, E Morel, O Montalescot, G Barone-Rochette, G Mansourati, J Cottin, Y Leclercq, F Belhassane, A Delarche, N Boccara, F Paganelli, F Clerc, J Schiele, F Aboyans, V Probst, V Berland, J Lefevre, T Citron, B Khintibidze, I Shaburishvili, T Pagava, Z Ghlonti, R Lominadze, Z Khabeishvili, G Hemetsberger, R Rauch-Krohnert, U Stratmann, M Appel, KF Schmidt, E Omran, H Stellbrink, C Dorsel, T Lianopoulos, E Marx, R Zirlik, A Schellenberg, D Heitzer, T Laufs, U Marx, N Gielen, S Winkelmann, B Behrens, S Sydow, K Simonis, G Muenzel, T Werner, N Leggewie, S Bocker, D Braun-Dullaeus, R Toursarkissian, N Jeserich, M Weissbrodt, M Schaeufele, T Weil, J Voller, H Waltenberger, J Natour, M Schmitt, S Steiner, S Heidenreich, L Gremmler, U Killat, H Rieker, W Patsilinakos, S Kartalis, A Manolis, A Sionis, D Liberopoulos, E Skoumas, I Athyros, V Vardas, P Parthenakis, F Alexopoulos, D Hahalis, G Lekakis, J Hatzitolios, A Ovando, SRF Valdovinos, PCM Benecke, JLA De Leon, ERR Yan, BPY Siu, DCW Turi, T Merkely, B Kiss, RG Ungi, I Lupkovics, G Nagy, L Katona, A Edes, I Muller, G Horvath, I Kapin, T Falukozy, J Kumbla, M Sandhu, M Annam, S Proddutur, NR Premchand, RK Mahajan, A Abhyanakar, AD Kerkar, P Govinda, RA Oomman, A Sinha, D Patil, SN Kahali, D Sawhney, J Joshi, AB Chaudhary, S Harkut, P Guha, S Porwal, S Jujjuru, S Pothineni, RB Monteiro, MR Khan, A Iyengar, SS Grewal, JS Chopda, M Fulwani, MC Patange, A Chopra, VK Goyal, NK Shinde, R Manakshe, GV Patki, N Sethi, S Munusamy, V Karna, S Adhyapak, S Pandurangi, U Mathur, R Kalashetti, S Bhagwat, A Raghuraman, B Yerra, SK Bhansali, P Borse, R Das, S Abdullakutty, J Saathe, S Abdullkutty, J Sathe, S Palimkar, P Atar, S Shechter, M Mosseri, M Arbel, Y Lotan, C Rosenschein, U Katz, A Henkin, Y Francis, A Klutstein, M Nikolsky, E Turgeman, Y Halabi, M Kornowski, R Jonas, M Amir, O Rozenman, Y Fuchs, S Hussein, O Gavish, D Vered, Z Caraco, Y Elias, M Tov, N Lishner, M Elias, N Piovaccari, G De Pellegrin, A Guardigli, G Licciardello, G Auguadro, C Cuccia, C Salvioni, A Musumeci, G Calabro, P Novo, S Faggiano, P De Cesare, NB Berti, S Cavallini, C Puccioni, E Galvani, M Tespili, M Piatti, P Palvarini, M De Luca, G Violini, R De Leo, A Filardi, PP Ferratini, M Ricca, V Dai, K Kamiya, H Ando, K Takeda, Y Morino, Y Hata, Y Kimura, K Kishi, K Michishita, I Uehara, H Higashikata, T Hirayama, A Hirooka, K Sakagami, S Taguchi, S Koike, A Fujinaga, H Koba, S Kozuma, K Kawasaki, T Ono, Y Shimizu, M Katsuda, Y Wada, A Shinke, T Kimura, T Ako, J Fujii, K Takahashi, T Sakamoto, T Furukawa, Y Sugino, H Mano, T Utsu, N Ito, K Haraguchi, T Ueda, Y Nishibe, A Masutani, M Fujimoto, K Yoon, JH Kim, SH Park, HS Chae, IH Kim, MH Jeong, MH Rha, S Kim, C Hong, T Tahk, SJ Kim, Y Busmane, A Pontaga, N Strelnieks, A Mintale, I Sime, I Petrulioniene, Z Kavaliauskiene, R Jurgaitiene, R Sakalyte, G Slapikas, R Norkiene, S Misonis, N Kibarskis, A Kubilius, R Bojovski, S Kedev, S Lozance, N Kjovkaroski, A Doncovska, S Ong, TK Kasim, S Maskon, O Kandasamy, B Yusoff, K Liew, HB Mohamed, WMIW Castillo, AG Calvillo, JC Campos, PF Fragoso, JCN Llamas, EAB Gamba, MAA Madrigal, JC Salas, LGG Rosas, EL Diaz, BG Vazquez, ES Ackar, AN Esperon, GAL Sanchez, CRM De Leon, MG Otero, RS Salmon, GF Rios, JA Ruiz, JAG Breedveld, RW Hoogslag, PAM Suryapranata, H Oomen, A Wiersma, JJ Van Der Wal, RMA Van Huysduynen-Monraats, PSH Karalis, I Verdel, GJE Brueren, BR Troquay, RPT Viergever, EP Al-Windy, NYY Bartels, GL Cornel, JH Hermans, WRM Herrman, JPR Bos, RJ Groutars, RGEJ Van Der Zwaan, CC Kaplan, R Ronner, E Groenemeijer, BE Bronzwaer, PNA Liem, AAH Rensing, BJWM Bokern, MJJA Nijmeijer, R Hersbach, FMRJ Willems, FF Gosselink, ATM Elliott, J Wilkins, G Fisher, R Scott, D Hart, H Stewart, R Harding, S Ternouth, I Fisher, N Aitken, D Anscombe, R Davidson, L Tomala, T Nygard, O Sparby, JA Andersen, K Gullestad, L Jortveit, J Munk, PS Singsaas, EG Halvorsen, S Hurtig, U Flores, RMC Ticona, JRC Velasquez, JRD Miguel, SAN Perez, ESS Chambilla, JMC Ayala, CAC Leon, RPC Gonzales, RJV Zuniga, JDH Cosavalente, LAC Mannucci, JEB Landeo, JH Navarro, NCL Concha, YMR Chavez, VER Hernandez, HAA Nunez, CAZ Ramos, WM Ferrolino, A Sy, RAG Tirador, L Sy, RG Matiga, G Coching, RM Bernan, A Rogelio, G Morales, DD Tan, E Sulit, DJ Wlodarczak, A Jaworska, K Skonieczny, G Pawlowicz, L Wojewod, P Busz-Papiez, B Bednarski, J Goch, A Staneta, P Dulak, E Budaj, A Saminsk, K Krasowski, W Sudnik, W Zurakowski, A Skorski, M Lysek, R Miklaszewicz, B Kubica, J Lipko, JA Kostarska-Srokosz, E Piepiorka, M Drzewiecka, A Sciborski, R Stasiewski, A Blicharski, T Bystryk, L Szpajer, M Korol, M Czerski, T Mirek-Bryniarska, E Gniot, J Lubinski, A Gorny, J Franek, E Raczak, G Szwed, H Monteiro, P Bastos, JM Pereira, HH Martins, D Morais, J Seixo, F Mendonca, C Botelho, A Minescu, B Istratoaie, O Tesloianu, DN Dorobantu, M Cristian, G Podoleanu, CGC Constantinescu, MCA Bengus, CM Militaru, C Rosu, D Parepa, IR Matei, AV Alexandru, TM Coman, I Cioranu, RS Dimulescu, D Shvarts, Y Orlikova, O Kobalava, Z Barbarash, OL Markov, V Lyamina, N Gordienko, A Zrazhevsky, K Vishnevsky, AY Gurevich, V Stryuk, R Lomakin, NV Bokarev, I Shalaev, S Khaisheva, L Chizhov, P Viktorova, I Osokina, N Akatova, E Chumakova, G Libov, I Voevoda, MI Tretyakova, TV Baranov, E Shustov, S Yakushin, S Gordeev, I Khasanov, N Reshetko, O Sotnikova, T Molchanova, O Nikolaev, K Gapon, L Baranova, E Shogenov, Z Kosmachova, E Karpov, Y Povzun, A Egorova, L Tyrenko, VV Ivanov, IG Kanorsky, S Simic, D Ivanovic, N Davidovic, G Tasic, N Asanin, MR Stojic, S Apostolovic, SR Ilic, S Putnikovic, B Stankovic, A Arandjelovic, A Radovanovic, S Ristic, AD Balinovac, J Dincic, DV Seferovic, P Dodic, S Dimkovic, S Poh, KK Ong, HY Micko, K Nociar, J Pella, D Fulop, P Hranai, M Palka, J Mazur, J Majercak, I Dzupina, A Fazekas, F Gonsorcik, J Bugan, V Selecky, J Kamensky, G Strbova, J Smik, R Dukat, A Olexa, P Zuran, I Poklukar, J Suligoj, NC Cevc, M Cyster, HP Ranjith, N Corbett, C Bayat, J Makotoko, EM Kapp, IE Basson, MMD Lottering, H Van Zyl, LJ Sebastian, PJ Pillay, T Saaiman, JA Commerford, PJ Cassimjee, S Ebrahim, IO Sarvan, M Mynhardt, JH Reuter, H Moodley, R Vida, M Fillat, ARC Peris, VB Jimenez, FF Marin, F Fernandez, JMC Gil-Extremera, B Diz, FW Garcia-Dorado, D Iniguez, A Fernandez, JT Gonzalez-Juanatey, JR Portales, JF Murillo, FC Pericas, LM Zamorano, JL Martin, MD Cortada, JB Martin, JJA Fernandez, JRD Fernandez, JFD Lledo, JAG Sales, JC Rodriguez, JB Tragant, GG Benedicto, A Gonzalez-Juanatey, C Potau, MC Perez, IP De La Tassa, CM Rincon, PLO Recena, JB Escudier, JM Payeras, AC Orcajo, NA Valdivielso, P Constantine, G Haniffa, R Tissera, N Amarasekera, S Fernando, N Jayawardena, J Santharaj, W Ekanayaka, R Mendis, S Senaratne, V Mayurathan, G Sirisena, T Rajapaksha, A Herath, JI Amarasena, N Berglund, S Rasmanis, G Witt, N Mourtzinis, G Nicol, P Hansen, O Romeo, S Jensen, SA Torstensson, I Ahremark, U Sundelin, T Moccetti, T Muller, C Mach, F Binder, R Tsai, WC Ueng, KC Lai, WT Liu, ME Hwang, JJ Yin, WH Hsieh, IC Kuo, JY Huang, TY Fang, CY Kaewsuwanna, P Soonfuang, W Jintapakorn, W Sukonthasarn, A Wongpraparut, N Sastravaha, K Sansanayudh, N Kehasukcharoen, W Piyayotai, D Chotnoparatpat, P Camsari, A Kultursay, H Mutlu, B Ersanli, M Demirtas, M Kirma, C Ural, E Koldas, L Karpenko, O Prokhorov, A Vakaluyk, I Myshanych, H Reshotko, D Batushkin, V Rudenko, L Kovalskyi, I Kushnir, M Tseluyko, V Mostovoy, Y Stanislavchuk, M Kyiak, Y Karpenko, Y Malynovsky, Y Klantsa, A Kutniy, O Amosova, E Tashchuk, V Leshchuk, O Rishko, M Kopytsya, M Yagensky, A Vatutin, M Bagriy, A Barna, OM Ushakov, O Dzyak, G Goloborodko, B Rudenko, A Zheleznyy, V Trevelyan, J Zaman, A Lee, K Moriarty, A Aggarwal, RK Clifford, P Wong, YK Iqbal, SM Subkovas, E Braganza, D Sarkar, D Storey, R Griffiths, H Mcclure, S Muthusamy, R Kurian, J Levy, T Barr, C Kadr, H Gerber, R Simaitis, A Soran, H Mathur, A Brodison, A Oliver, R Mudawi, T Reynolds, T Sharman, D Butler, R Wilkinson, P Lip, GYH Halcox, J Vardi, G Baldari, D Brabham, D Treasure, C Dahl, C Palmer, B Wiseman, A Puri, S Mohart, AE Ince, C Flores, E Wright, S Cheng, SC Rosenberg, M Rogers, W Kosinski, E Forgosh, L Waltman, J Khan, M Shoukfeh, M Dagher, G Lieber, I Kumar, P East, C Krichmar, P White, L Knickelbine, T Haldis, T Gillespie, E Suh, D Arif, I Akhter, F Carlson, E D'Urso, M El-Ahdab, F Nelson, W Harris, B Cohen, S Carter, L Sabatino, K Haddad, T Malik, A Rao, S Mulkay, A Jovin, I Klancke, K Malhotra, V Devarapalli, SK Koren, M Chandna, H Dodds, G Janik, M Moran, J Sumner, A Kobayashi, J Davis, W Yazdani, S Pasquini, J Thakkar, M Vedere, A Leimbach, W Rider, J Singh, N Shah, AV Janosik, D Pepine, C Berman, B Gelormini, J Daniels, C Keating, F Kondo, NI Shetty, S Waider, W Takata, T Abu-Fadel, M Shah, V Aggarwal, R Izzo, M Kumar, A Hattler, B Link, C Bortnick, A Kinzfogl, G Ghitis, A Larry, J Teufel, E Kuhlman, P Mclaurin, B Zhang, WW Thew, S Abbas, J White, M Ranadive, N Gring, C Henderson, D Schuchard, T Farhat, N Kline, G Mahal, S Whitaker, J Speirs, S Andersen, R Daboul, N Horwitz, P Ponce, G Jafar, Z Mcgarvey, J Panchal, V Voyce, S Blok, T Sheldon, W Azizad, MM Schmalfuss, C Picone, M Herzog, W Lindsey, J Nowins, R Lepor, N El Shahawy, M Weintraub, H Irimpen, A May, W Galski, T Chu, A Mody, F Hodes, Z Rose, G Fairlamb, J Lambert, C Raisinghani, A Abbate, A King, M Carey, C Gerber, J Younis, L Park, H Vidovich, M Knutson, T Friedman, D Chaleff, F Loussararian, A Rozeman, P Kimmelstiel, C Silver, K Foster, M Tonnessen, G Amlani, M Wali, A Malozzi, C Wattanakit, K O'Donnell, PJ Singal, D Jaffrani, N Banuru, S Fisher, D Xenakis, M Perlmutter, N Bhagwat, R Strader, J Akyea-Djamson, A Labroo, A Marais, HJ Claxton, E Berk, M Rossi, P Joshi, P Khaira, AS Kumkumian, G Lupovitch, S Purow, J Welka, S Hoffman, D Fischer, S Soroka, E Eagerton, D Pancholy, S Ray, M Farrar, M Pollock, S French, WJ Diamantis, S Gimple, L Neustel, M Schwartz, S Pereira, E Spriggs, D Strain, J Vo, A Chane, M Hall, J Vijay, N Lotun, K Lester, FM Nahhas, A Pope, T Nager, P Vohra, R Bashir, R Ahmed, H Berlowitz, M Fishberg, R Barrucco, R Yang, E Radin, M Sporn, D Eisenberg, S Landzberg, J Mcgough, M Turk, S Schwartz, M Sundram, PS Jain, D Zainea, M Bayron, C Karlsberg, R Lui, H Keen, W Westerhausen, D Khurana, S Agarwal, H Birchem, J Penny, W Chang, M Murphy, S Schifferdecker, B Gilbert, JM Chalavarya, G Eaton, C Schmedtje, JF Christenson, S Denham, D Macdonell, A Gibson, P Rahman, A Al Joundi, T Conrad, G Kotha, P Love, M Giesler, G Rubenstein, H Akright, L Krawczyk, J Wells, T Welker, J Foster, R Gilmore, R Anderson, J Jacoby, D Gardner, G Dandillaya, R Vora, K Kostis, J Hunter, J Laxson, D Ball, E Camp, A Lopes, R Egydio, F Kawakami, A Oliveira, J Wozniak, J Matthews, A Ratky, C Valiris, J Berdan, L Hepditch, A Quintero, K Rorick, T Westbrook, M Pascual, A Rovito, C Bezault, M Drouet, E Simon, T Alsweiler, C Luyten, A Aylward, P Butters, J Griffith, L Shaw, M Hagstrom, E Grunberg, L Islam, S Bregeault, MF Bougon, N Faustino, D Fontecave, S Murphy, J Tamby, JF Verrier, M Agnetti, V Andersen, D Badreddine, E Bekkouche, M Bouancheau, C Brigui, I Brocklehurst, M Cianciarulo, J Devaul, D Domokos, S Gache, C Gobillot, C Guillou, S Healy, J Heath, M Jaiwal, G Javierre, C Labeirie, J Monier, M Morales, U Mrabti, A Mthombeni, B Okan, B Smith, L Sheller, J Sopena, S Pellan, V Benbernou, F Bengrait, N Lamoureux, M Kralova, K Scemama, M Bejuit, R Coulange, A Berthou, C Repincay, J Lorenzato, C Etienne, A Gouet, V Loizeau, V Normand, M Ourliac, A Rondel, C Adamo, A Beltran, P Barraud, P Dubois-Gache, H Halle, B Metwally, L Mourgues, M Sotty, M Vincendet, M Cotruta, R Zhu, CY Fournie-Lloret, D Morrello, C Perthuis, A Picault, P Zobouyan, I |
| author2_role | author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| author_browse | Abbas, J Abbate, A Abdullakutty, J Abdullkutty, J Abhyanakar, AD Aboyans, V Abrantes, JAM Abu-Fadel, M Acevedo, M Ackar, AN Adamkova, V Adamo, A Adhyapak, S Agarwal, H Aggarwal, R Aggarwal, RK Agnetti, V Aguirre, A Ahmed, H Ahremark, U Airaksinen, JK Aitken, D Akatova, E Akhter, F Ako, J Akright, L Akyea-Djamson, A Al Joundi, T Al-Windy, NYY Alan, D Alexander, JH Alexander, K Alexandru, TM Alexopoulos, D Alings, M Allende, JCM Alsweiler, C Alvarisqueta, AF Amarasekera, S Amarasena, N Amir, O Amlani, M Amosova, E Amuchastegui, M Andersen, D Andersen, K Andersen, R Anderson, J Ando, K Annam, S Anscombe, R Apostolovic, SR Appel, KF Arandjelovic, A Araneda, G Arbel, Y Arif, I Armaganijan, L Aroney, C Arroyo, JAC Arstall, MA Asanin, MR Atar, S Athyros, V Auguadro, C Ayala, CAC Aylward, P Aylward, PE Ayoub, JCA Azizad, MM Badreddine, E Bagai, A Bagriy, A Bahit, MC Bai, F Baldari, D Balinovac, J Ball, E Bang, LE Banuru, S Barakovic, F Baranov, E Baranova, E Barbarash, OL Barbato, E Barna, OM Barone-Rochette, G Barr, C Barraud, P Barrucco, R Bartels, GL Bashir, R Basson, MMD Bastos, JM Bata, I Batushkin, V Bayat, J Bayron, C Beauloye, C Bednarski, J Behrens, S Bejuit, R Bekkouche, M Belhassane, A Beltran, P Benbernou, F Bencic, ML Benecke, JLA Benedicto, A Bengrait, N Bengus, CM Benov, HO Berdan, L Berger, R Berglund, S Berk, M Berland, J Berli, MA Berlowitz, M Berman, B Bernan, A Berthou, C Berti, S Bezault, M Bhagwat, A Bhagwat, R Bhansali, P Bhatt, DL Binder, R Birchem, J Bittner, VA Blicharski, T Blok, T Blumberg, EDS Boccara, F Bocker, D Bodanese, LC Bojovski, S Bokarev, I Bokern, MJJA Bonfanti, AJC Bono, JOE Bordonava, AP Borse, R Bortnick, A Bos, RJ Botelho, A Botelho, RV Botia, DCL Bottcher, M Bouancheau, C Bougon, N Bourgeois, R Brabham, D Braganza, D Brasca, DFG Braun-Dullaeus, R Breedveld, RW Bregeault, MF Brennan, JM Brigui, I Brocklehurst, M Brodison, A Bronzwaer, PNA Brueren, BR Budaj, A Bugan, V Busmane, A Busz-Papiez, B Butler, R Butters, J Bystryk, L Caccavo, A Caime, GD Calabro, P Calvillo, JC Camp, A Campos, PF Camsari, A Car, S Caraco, Y Carey, C Carlson, E Carnero, GS Carroll, PA Cartasegna, LR Carter, L Caruso, OC Cassimjee, S Castadot, M Castillo, AG Cavallini, C Cerqueira, MJAG Cestari, HG Cevc, M Cha, J Chae, IH Chaitman, B Chalavarya, G Chaleff, F Chambilla, JMC Chandna, H Chane, M Chang, M Chaudhary, S Chavez, VER Chen, D Chen, JY Chen, YD Cheng, SC Cheng, XS Chiang, CE Chizhov, P Chopda, M Chopra, VK Chotnoparatpat, P Christenson, S Chu, A Chua, T Chumakova, G Chumburidze, V Cianciarulo, J Cioranu, RS Citron, B Claeys, M Claxton, E Clemmensen, P Clerc, J Cleveland, D Clifford, P Clifton, S Coching, RM Codutti, OR Cohen, S Collins, N Colombo, HR Colquhoun, D Coman, I Commerford, PJ Concha, YMR Conrad, G Constantine, G Constantinescu, MCA Convens, C Cools, F Corbett, C Cornel, JH Cortada, JB Cosavalente, LAC Costa, F Costamagna, O Coste, P Cotruta, R Cottin, Y Coufal, Z Coulange, A Coverdale, SGM Cristian, G Cuccia, C Cui, L Cyster, HP Czerski, T D'Urso, M Daboul, N Dagher, G Dahl, C Dai, K Dalby, AJ Danchin, N Dandillaya, R Daniels, C Das, S Davidovic, G Davidsen, F Davidson, L Davies, R Davis, W De Cesare, NB De La Tassa, CM De Leo, A De Leon, ERR De Leon, MG De Lima, AEA De Luca, G De Pellegrin, A De Salazar, DIM De Silva, HA De Wolf, L DeVore, AD Delarche, N Deloatch, S Demirtas, M Denham, D Devarapalli, SK Devaul, D Diamantis, S Diaz, A Diaz, BG Diaz, R Dick, R Dickey, S Dilic, M Dimkovic, S Dimov, BI Dimulescu, D Dincic, DV Ding, CH Dion, D Diz, FW Dodds, G Dodic, S Dombrowski, K Domokos, S Doncovska, S Dong, SH Dong, YG Dorobantu, M Dorsel, T Dran, RD Drexel, H Drouet, E Drzewiecka, A Dubois-Gache, H Ducas, J Ducrocq, G Duda, N Dujardin, K Dukat, A Dulak, E Dupuis, R Durak-Nalbantic, A Duran, ROG Duronto, EA Dzupina, A Dzyak, G Eagerton, D Eapen, Z East, C Eaton, C Ebrahim, IO Edelberg, JM Edes, I Egorova, L Egydio, F Eisenberg, S Ekanayaka, R El Shahawy, M El-Ahdab, F Elias, M Elias, N Eliaschewitz, FG Elliott, J Endsley, P Eppinger, A Erglis, A Ersanli, M Escudier, JM Esperon, GAL Etienne, A Fadlallah, H Faes, D Faggiano, P Fairlamb, J Falukozy, J Fan, ZC Fang, CY Fang, WY Farhat, N Farrar, M Faustino, D Fazekas, F Fazlibegovic, E Feitosa, GS Fell, D Feng, Y Fernandez, JFD Fernandez, JMC Fernandez, JRD Fernandez, JT Fernandez, M Fernando, N Ferrari, E Ferratini, M Ferrolino, A Filardi, PP Fillat, ARC Fischer, S Fishberg, R Fisher, D Fisher, N Fisher, R Florenzano, F Flores, E Flores, REO Flores, RMC Fong, P Fontecave, S Forgosh, L Foster, M Foster, R Fournie-Lloret, D Fragoso, JCN Francis, A Franek, E Fras, Z French, WJ Friedman, D Frost, L Fu, GS Fuchs, S Fujii, K Fujimoto, K Fujinaga, H Fulop, P Fulwani, MC Furukawa, Y Gache, C Galski, T Galvani, M Gamba, MAA Gapon, L Garcia-Dorado, D Gardner, G Garrahy, PJ Garrido, M Gavish, D Ge, JB Gelormini, J Gerber, J Gerber, R Ghitis, A Ghlonti, R Gibson, P Gielen, S Giesler, G Gil-Extremera, B Gilbert, JM Gillespie, E Gilmore, R Gimple, L Giordano, JA Giorgeto, FE Gislason, G Giuliano, ME Gniot, J Gobillot, C Goch, A Goloborodko, B Gonsorcik, J Gonzales, RJV Gonzalez-Juanatey, C Gonzalez-Juanatey, JR Goodman, SG Gordeev, I Gordienko, A Gorny, J Goronja, B Gosselin, G Gosselink, ATM Gotcheva, NN Gouet, V Govinda, RA Goyal, NK Gremmler, U Grewal, JS Griffith, L Griffiths, H Gring, C Groenemeijer, BE Groutars, RGEJ Grunberg, L Guardigli, G Guerrero, RAA Guha, S Guillou, S Gullestad, L Guneri, S Guo, Y Gurevich, V Guzman, PN Haddad, T Hagstrom, E Hahalis, G Halabi, M Halcox, J Hald, F Haldis, T Hall, J Halle, B Halvorsen, S Hameed, A Haniffa, R Hanotin, C Hansen, O Haraguchi, T Harding, S Harkut, P Harrington, RA Harris, B Harrison, RW Hart, H Hata, Y Hattler, B Hatzitolios, A Healy, J Heath, M Hedman, A Heidenreich, L Heinc, P Heitzer, T Hemetsberger, R Henderson, D Henkin, Y Hepditch, A Herath, JI Herazo, AS Hermans, K Hermans, WRM Hernandez, HAA Herrman, JPR Hersbach, FMRJ Herzog, W Hess, CN Higashikata, T Higuera, JD Hii, CLS Hirayama, A Hirooka, K Hlatky, MA Hoag, G Hodes, Z Hoffer, E Hoffman, D Hominal, MA Hong, T Hoogslag, PAM Hoppe, U Horak, D Horowitz, J Horvath, I Horwitz, P Hove, JD Hrabar, AD Hranai, M Hsieh, IC Huang, L Huang, SA Huang, TY Huang, WJ Huber, K Huidobro, L Huikuri, H Hunter, J Hurtig, U Hussein, O Huynh, T Hwang, JJ Ilic, S Ilieva-Pandeva, KA Ince, C Iniguez, A Iqbal, SM Irimpen, A Islam, S Istratoaie, O Ito, K Ivanov, IG Ivanova, R Ivanovic, N Iyengar, SS Izzo, M Jacoby, D Jafar, Z Jaffrani, N Jain, D Jaiwal, G Janik, M Janosik, D Jaramillo, N Jatin, FGM Javierre, C Jaworska, K Jayawardena, J Jensen, SA Jeong, MH Jeppesen, J Jeserich, M Jiang, WH Jimenez, FF Jintapakorn, W Johansen, PB Jonas, M Jones, WS Jordan, JD Jorge, JCM Jortveit, J Joshi, AB Joshi, P Jovin, I Jujjuru, S Jukema, JW Juonala, M Jure, HO Jurgaitiene, R Kadr, H Kaewsuwanna, P Kahali, D Kaikkonen, K Kaiser, S Kalashetti, S Kalil, R Kamensky, G Kamiya, H Kandasamy, B Kanorsky, S Kapin, T Kaplan, R Kapp, IE Karalis, I Karlsberg, R Karna, S Karpenko, O Karpenko, Y Karpov, Y Kartalis, A Kasim, S Katona, A Katsuda, Y Katz, A Kaucak, V Kavaliauskiene, R Kawakami, A Kawasaki, T Ke, YN Keating, F Kedev, S Keen, W Kehasukcharoen, W Kelsey, SF Kerkar, P Khabeishvili, G Khaira, AS Khaisheva, L Khan, A Khan, M Khasanov, N Khintibidze, I Khurana, S Kibarskis, A Kichukov, KN Killat, H Kim, C Kim, HS Kim, MH Kim, SH Kim, Y Kimmelstiel, C Kimura, K Kimura, T King, M Kinzfogl, G Kirma, C Kishi, K Kiss, RG Kiviniemi, T Kjovkaroski, A Klancke, K Klantsa, A Klausen, IC Kline, G Klutstein, M Knickelbine, T Knowles, JW Knutson, T Koba, S Kobalava, Z Kobayashi, J Koike, A Koldas, L Kolls, BJ Kondo, NI Kong, DF Kopytsya, M Koren, M Kormann, A Kornder, J Kornowski, R Korol, M Kosinski, E Kosmachova, E Kostarska-Srokosz, E Kostis, J Kotha, P Kouz, S Kovalskyi, I Kozuma, K Kralova, K Krasowski, W Krawczyk, J Krichmar, P Kristensen, KS Kristjan, A Krstulovic, SM Kubica, J Kubilius, R Kuchar, J Kuhlman, P Kultursay, H Kumar, A Kumar, P Kumbla, M Kumkumian, G Kuo, JY Kurian, J Kushnir, M Kutniy, O Kyiak, Y Labarta, MHB Labeirie, J Labroo, A Lai, C Lai, WT Lambert, C Lamoureux, M Landeo, JH Landzberg, J Larry, J Larsen, J Laucevicius, A Laufs, U Laxson, D Lazov, PV Leaes, PE Leclercq, F Lecorps, G Lee, K Lefevre, T Leggewie, S Lehman, SJ Leimbach, W Lekakis, J Leon, RPC Leonardi, S Leone, A Lepage, S Lepor, N Leshchuk, O Lester, FM Leung, R Levy, T Li, HM Li, JP Li, TC Li, X Li, XD Li, Y Lianopoulos, E Liberman, A Liberopoulos, E Libov, I Licciardello, G Lieber, I Liem, AAH Liew, HB Lillis, L Lin, JX Lin, WH Lin, XF Lindsey, J Linhart, A Link, C Lip, GYH Lipko, JA Lishner, M Liu, ME Liu, SW Llamas, EAB Lledo, JAG Llois, S Loizeau, V Lomakin, NV Lomholdt, JD Lominadze, Z Lopes, R Lopes, RD Lopez, GAR Lopez, R Lopez, RB Lopez-Jaramillo, P Lorenzato, C Lorenzatti, AJ Lotan, C Lottering, H Lotun, K Loussararian, A Love, M Lozada, HJG Lozance, N Lu, QH Lubinski, A Luciardi, HL Lui, H Luo, ZR Lupkovics, G Lupovitch, S Luquez, HA Luyten, A Lyamina, N Lysek, R MacDonald, P Macdonell, A Mach, F Machado, L Machova, V Mackinnon, IJ Madrigal, JC Mahaffey, KW Mahajan, A Mahal, S Maia, LN Majercak, I Makotoko, EM Malhotra, V Malik, A Malozzi, C Malynovsky, Y Manakshe, GV Manenti, ERFF Mannucci, JEB Mano, T Manolis, A Mansourati, J Marais, HJ Marcus, J Marin, F Marin, JA Markov, DT Markov, V Maron, DJ Martin, JJA Martin, MD Martins, D Martsin, K Marusincova, I Marx, N Marx, R Maskon, O Masutani, M Matei, AV Mathews, R Mathur, A Mathur, R Matiga, G Matthews, A Matuska, J May, O May, W Mayurathan, G Mazur, J Mcclure, S Mcgarvey, J Mcgough, M Mclaurin, B Mehta, RH Mehta, S Meloni, C Mendis, S Mendonca, C Mendoza, JLA Mentz, RJ Merkely, B Metwally, L Michalaros, YL Michaud, N Michishita, I Micko, K Midzic, Z Miguel, SAN Miklaszewicz, B Mileta, D Milicic, D Militaru, C Mincheva, VM Minescu, B Mintale, I Mirek-Bryniarska, E Misonis, N Moccetti, T Mody, F Mohamed, WMIW Mohart, AE Molchanova, O Mollov, MN Monier, M Montalescot, G Montana, OR Montecinos, H Monteiro, MR Monteiro, P Moodley, R Morais, J Morales, DD Morales, U Moran, J Moreira, HG Morel, O Moriarty, A Moriarty, PM Morino, Y Morisset, A Morrello, C Moryusef, A Mosseri, M Mostovoy, Y Motovska, Z Mourgues, M Mourtzinis, G Mrabti, A Mthombeni, B Mudawi, T Muenzel, T Mulkay, A Muller, C Muller, G Munk, PS Munusamy, V Murillo, FC Murin, J Murphy, J Murphy, S Muslibegovic, A Musumeci, G Muthusamy, R Mutlu, B Mynhardt, JH Myshanych, H Nager, P Nagy, L Nahhas, A Nahuelpan, L Nani, S Naplava, R Natour, M Navarro, NCL Nelson, W Neuenschwander, F Neustel, M Nicol, P Nicolau, JC Nielsen, PK Nielsen, T Nieminen, MS Nigro, F Nijmeijer, R Nikolaev, K Nikolov, FP Nikolsky, E Nishibe, A Nociar, J Nogareda, G Norkiene, S Normand, M Novaretto, LP Novo, S Novoa, F Novotny, V Nowins, R Nunez, CAZ Nygard, O O'Donnell, PJ Okan, B Olexa, P Olivares, C Oliveira, J Oliver, R Olsson, AG Omran, H Ong, HY Ong, TK Ono, Y Oomen, A Oomman, A Orcajo, NA Orlikova, O Osokina, N Ostadal, P Otero, RS Ourliac, A Ovando, SRF Paganelli, F Pagava, Z Palimkar, P Palka, J Palmer, B Palvarini, M Panchal, V Pancholy, S Pandey, A Pandurangi, U Parada, JC Parepa, IR Park, H Park, HS Parkhomenko, A Parthenakis, F Pascual, A Pasquini, J Patange, A Patel, CB Paterlini, GA Patil, SN Patki, N Patocchi, CA Patsilinakos, S Pawlowicz, L Payeras, AC Pearce, S Pecin, I Pella, D Pellan, V Peng, DQ Penny, W Pepine, C Pereira, E Pereira, HH Pereira, SB Perez, ESS Perez, IP Perez, L Pericas, LM Peris, VB Perkins, L Perlmutter, N Persic, V Perthuis, A Pesant, Y Petranov, SL Petrulioniene, Z Piatti, P Picault, P Picone, M Piepiorka, M Pillay, T Pimentel, P Pincetti, C Pintaric, H Piovaccari, G Pirenne, B Piyayotai, D Podoleanu, CGC Podpera, I Poh, KK Pojskic, B Poklukar, J Pollock, S Ponce, G Pontaga, N Pope, T Pordy, R Portales, JF Porthan, K Porwal, S Posio, P Potau, MC Pothineni, RB Potthoff, S Poulsen, SH Povolny, P Povsic, TJ Povzun, A Precoma, DB Premchand, RK Prieto, JC Probst, V Proddutur, NR Prokhorov, A Prvulovic, D Puccioni, E Puri, S Purow, J Putnikovic, B Puymirat, E Qu, BM Quintero, K Raczak, G Radin, M Radovanovic, S Raev, DH Raffel, O Raffo, CA Raghuraman, B Rahman, A Raisinghani, A Rajapaksha, A Ramos, WM Ranadive, N Ranjith, N Rao, S Rasmanis, G Ratky, C Rauch-Krohnert, U Raungaard, B Ray, KK Ray, M Recena, JB Rech, R Reiner, Z Reis, G Reis, HJL Rensing, BJWM Repincay, J Reshetko, O Reshotko, D Reuter, H Reynolds, T Rha, S Ricca, V Rider, J Rieker, W Rincon, PLO Rios, JA Rishko, M Ristic, AD Ritt, LEF Roberts-Thomson, P Robinson, S Rodes-Cabau, J Rodriguez, JB Roe, MT Rogelio, G Rogers, JF Rogers, W Rokyta, R Romeo, S Rondel, C Ronner, E Roosen, J Rorick, T Rosas, EL Rose, G Rosenberg, M Rosenschein, U Rosenson, R Rossi, P Rossi, PRF Rosu, D Rouleau, JL Rovito, C Rozeman, P Rozenman, Y Rubenstein, H Rudenko, A Rudenko, L Ruiz, JAG Ruiz, RLF Saaiman, JA Saathe, S Saavedra, SS Sabatino, K Sabbah, E Sader, M Sakagami, S Sakalyte, G Sakamoto, T Salas, LGG Sales, JC Salmon, GF Salomone, R Salvioni, A Saminsk, K Sanchez, CRM Sandhu, M Sansanayudh, N Santharaj, W Saporito, W Sarkar, D Sarvan, M Sasiela, WJ Sassone, SA Sastravaha, K Sathe, S Savard, D Sawhney, J Scemama, M Schaeufele, T Schellenberg, D Schiavi, LB Schiele, F Schifferdecker, B Schmalfuss, C Schmedtje, JF Schmidberg, JM Schmidt, E Schmitt, S Schuchard, T Schwartz, GG Schwartz, M Schwartz, S Sciborski, R Scott, D Sebastian, PJ Seferovic, P Seixo, F Selecky, J Senaratne, M Senaratne, V Sethi, S Shaburishvili, T Shah, AV Shah, BR Shah, V Shalaev, S Sharman, D Shaw, J Shaw, M Shechter, M Shehova-Yankova, NS Sheldon, W Sheller, J Sherwood, MW Shetty, S Shi, XB Shimizu, M Shinde, R Shinke, T Shogenov, Z Shou, XL Shoukfeh, M Shustov, S Shvarts, Y Sijbrands, EJG Sikic, J Silva, PGMD Silva, RP Silva, SIB Silveira, JA Silver, K Simaitis, A Sime, I Simic, D Simon, T Simonis, G Simoons, ML Singal, D Singh, N Singsaas, EG Sinha, D Sinnaeve, P Sionis, D Sirisena, T Siu, DCW Skonieczny, G Skorski, M Skoumas, I Slapikas, R Smik, R Smith, L Soggia, AP Soonfuang, W Soopold, U Soots, M Sopena, S Soran, H Soroka, E Sotnikova, T Sotty, M Sousa, L Souza, WKSB Soward, A Sparby, JA Speirs, S Spinar, J Sporn, D Spriggs, D Sritara, P Stambuk, K Staneta, P Stanislavchuk, M Stankovic, A Starcevic, B Starmer, G Stasek, J Stasiewski, A Steg, PG Steiner, S Stellbrink, C Stewart, R Stojic, S Stone, J Storey, R Strader, J Strain, J Stratmann, M Strbova, J Strelnieks, A Striekwold, H Stringfellow, K Strozzi, M Stryuk, R Su, GH Su, X Subkovas, E Sudnik, W Sugino, H Suh, D Sujjavanich, D Sukonthasarn, A Suligoj, NC Sulit, DJ Sumner, A Sun, YM Sun, YX Sundelin, T Sundram, PS Suryapranata, H Sussex, B Svab, P Sy, RAG Sy, RG Sydow, K Szarek, M Szpajer, M Szwed, H Taguchi, S Tahk, SJ Takahashi, T Takata, T Takeda, Y Tamby, JF Tan, E Tashchuk, V Tasic, N Taskinen, MR Taurio, J Ternouth, I Terzic, I Tesloianu, DN Tespili, M Teufel, E Thakkar, M Thew, S Ticona, JRC Tirador, L Tissera, N Todorov, GV Toma, M Tomala, T Tomulic, V Tonnessen, G Torstensson, I Toursarkissian, N Tov, N Tragant, GG Treasure, C Tretyakova, TV Trevelyan, J Triana, MAU Tricoci, P Troquay, RPT Trotter, C Tsai, WC Tse, HF Tseluyko, V Tumbev, HS Tunon, J Turgeman, Y Turi, T Turk, S Tyrenko, VV Tzekova, ML Ueda, Y Uehara, H Ueng, KC Ungi, I Ural, E Ushakov, O Utsu, N Vahula, V Vakaluyk, I Valdivielso, P Valdovinos, PCM Valgimigli, M Valiris, J Vallejo, GS Vallejos, JA Van Der Wal, RMA Van Der Zwaan, CC Van Diepen, SFP Van Huysduynen-Monraats, PSH Van Zyl, LJ Vardas, P Vardi, G Varleta, P Vatutin, M Vazquez, ES Vedere, A Vejar, M Velasquez, JRD Velcheva, ES Verdel, GJE Vered, Z Verrier, M Vervoort, G Vico, ML Vida, M Videbaek, L Vidotti, MH Vidovich, M Viergever, EP Viigimaa, M Vijay, N Vijayaraghavan, R Vikman, S Viktorova, I Vilamajo, OAG Vincendet, M Violini, R Vishnevsky, AY Vizel, S Vo, A Voevoda, MI Vohra, R Voller, H Vora, K Voyce, S Vrolix, MCM Vulic, D Vuurmans, T Wada, A Waider, W Waisman, GD Waites, JH Wali, A Walichiewicz, PM Waltenberger, J Waltman, J Wang, JA Wang, JF Wang, JZ Wattanakit, K Wei, M Weidinger, F Weil, J Weintraub, H Weissbrodt, M Welka, S Welker, J Wells, T Werner, N Westbrook, M Westerhausen, D Whitaker, J White, HD White, L White, M Wiersma, JJ Wilkins, G Wilkinson, P Willems, FF Wilson, MD Winkelmann, B Wiseman, A Witt, N Wlodarczak, A Wojewod, P Wollaert, B Wong, YK Wongpraparut, N Wozniak, J Wright, S Wu, C Xavier, D Xenakis, M Xu, BA Xu, DL Xu, XP Xu, YZ Yagensky, A Yakushin, S Yan, ATK Yan, BPY Yanez, M Yang, E Yang, XC Yang, XJ Yao, ZH Yazdani, S Yerra, SK Yin, WH Yong, H Yoon, JH Younis, L Yu, YH Yuan, ZY Yusoff, K Zahger, D Zaidman, CJ Zainea, M Zaman, A Zamorano, JL Zapata, G Zdravko, B Zeiher, AM Zhang, RY Zhang, WW Zhang, XL Zhang, Z Zhao, XS Zheleznyy, V Zheng, Y Zheng, ZQ Zhou, YJ Zhu, CY Zhu, H Zhu, JH Zijlstra, LE Zirlik, A Zizka, J Zobouyan, I Zong, WX Zrazhevsky, K Zuniga, JDH Zurakowski, A Zuran, I Zweiker, R de Santos, MON de Silva, HA de Souza, JA |
| author_facet | Jukema, JW Szarek, M Zijlstra, LE de Silva, HA Bhatt, DL Bittner, VA Diaz, R Edelberg, JM Hanotin, C Harrington, RA Moryusef, A White, HD Zeiher, AM Schwartz, GG Steg, PG Tricoci, P Mahaffey, KW Lecorps, G Pordy, R Sasiela, WJ Drexel, H Sinnaeve, P Dilic, M Gotcheva, NN Goodman, SG Prieto, JC Yong, H Lopez-Jaramillo, P Pecin, I Reiner, Z Poulsen, SH Viigimaa, M Nieminen, MS Danchin, N Chumburidze, V Tse, HF Xavier, D Zahger, D Valgimigli, M Kim, HS Erglis, A Laucevicius, A Lopez, R Lopez, GAR Alings, M Chua, T Murin, J Fras, Z Dalby, AJ Tunon, J De Silva, HA Chiang, CE Sritara, P Guneri, S Parkhomenko, A Ray, KK Moriarty, PM Roe, MT Chaitman, B Kelsey, SF Olsson, AG Rouleau, JL Simoons, ML Alexander, K Meloni, C Rosenson, R Sijbrands, EJG Alexander, JH Armaganijan, L Bagai, A Bahit, MC Brennan, JM Clifton, S DeVore, AD Deloatch, S Dickey, S Dombrowski, K Ducrocq, G Eapen, Z Endsley, P Eppinger, A Harrison, RW Hess, CN Hlatky, MA Jordan, JD Knowles, JW Kolls, BJ Kong, DF Leonardi, S Lillis, L Maron, DJ Marcus, J Mathews, R Mehta, RH Mentz, RJ Moreira, HG Patel, CB Pereira, SB Perkins, L Povsic, TJ Puymirat, E Jones, WS Shah, BR Sherwood, MW Stringfellow, K Sujjavanich, D Toma, M Van Diepen, SFP Wilson, MD Yan, ATK Lopes, RD Trotter, C Schiavi, LB Garrido, M Alvarisqueta, AF Sassone, SA Bordonava, AP De Lima, AEA Schmidberg, JM Duronto, EA Caruso, OC Novaretto, LP Hominal, MA Montana, OR Caccavo, A Vilamajo, OAG Lorenzatti, AJ Cartasegna, LR Paterlini, GA Mackinnon, IJ Caime, GD Amuchastegui, M Salomone, R Codutti, OR Jure, HO Bono, JOE Hrabar, AD Vallejos, JA Guerrero, RAA Novoa, F Patocchi, CA Zaidman, CJ Giuliano, ME Dran, RD Vico, ML Carnero, GS Guzman, PN Allende, JCM Brasca, DFG Labarta, MHB Nani, S Blumberg, EDS Colombo, HR Liberman, A Luciardi, HL Waisman, GD Berli, MA Duran, ROG Cestari, HG Luquez, HA Giordano, JA Saavedra, SS Zapata, G Costamagna, O Llois, S Waites, JH Collins, N Soward, A Aylward, PE Hii, CLS Shaw, J Arstall, MA Horowitz, J Rogers, JF Colquhoun, D Flores, REO Roberts-Thomson, P Raffel, O Lehman, SJ Aroney, C Coverdale, SGM Garrahy, PJ Starmer, G Sader, M Carroll, PA Dick, R Zweiker, R Hoppe, U Huber, K Berger, R Weidinger, F Faes, D Hermans, K Pirenne, B Leone, A Hoffer, E Vrolix, MCM De Wolf, L Wollaert, B Castadot, M Dujardin, K Beauloye, C Vervoort, G Striekwold, H Convens, C Roosen, J Barbato, E Claeys, M Cools, F Terzic, I Barakovic, F Midzic, Z Pojskic, B Fazlibegovic, E Durak-Nalbantic, A Vulic, D Muslibegovic, A Goronja, B Reis, G Sousa, L Nicolau, JC Giorgeto, FE Silva, RP Maia, LN Rech, R Rossi, PRF Cerqueira, MJAG Duda, N Kalil, R Kormann, A Abrantes, JAM Pimentel, P Soggia, AP de Santos, MON Neuenschwander, F Bodanese, LC Michalaros, YL Eliaschewitz, FG Vidotti, MH Leaes, PE Botelho, RV Kaiser, S Manenti, ERFF Precoma, DB Jorge, JCM Silva, PGMD Silveira, JA Saporito, W Marin, JA Feitosa, GS Ritt, LEF de Souza, JA Costa, F Souza, WKSB Reis, HJL Machado, L Ayoub, JCA Todorov, GV Nikolov, FP Velcheva, ES Tzekova, ML Benov, HO Petranov, SL Tumbev, HS Shehova-Yankova, NS Markov, DT Raev, DH Mollov, MN Kichukov, KN Ilieva-Pandeva, KA Ivanova, R Mincheva, VM Lazov, PV Dimov, BI Senaratne, M Stone, J Kornder, J Pearce, S Dion, D Savard, D Pesant, Y Pandey, A Robinson, S Gosselin, G Vizel, S Hoag, G Bourgeois, R Morisset, A Sabbah, E Sussex, B Kouz, S MacDonald, P Diaz, A Michaud, N Fell, D Leung, R Vuurmans, T Lai, C Nigro, F Davies, R Nogareda, G Vijayaraghavan, R Ducas, J Lepage, S Mehta, S Cha, J Dupuis, R Fong, P Rodes-Cabau, J Fadlallah, H Cleveland, D Huynh, T Bata, I Hameed, A Pincetti, C Potthoff, S Acevedo, M Aguirre, A Vejar, M Yanez, M Araneda, G Fernandez, M Perez, L Varleta, P Florenzano, F Huidobro, L Raffo, CA Olivares, C Nahuelpan, L Montecinos, H Chen, JY Dong, YG Huang, WJ Wang, JZ Huang, SA Yao, ZH Li, X Cui, L Lin, WH Sun, YM Wang, JF Li, JP Zhang, XL Zhu, H Chen, D Huang, L Dong, SH Su, GH Xu, BA Su, X Cheng, XS Lin, JX Zong, WX Li, HM Feng, Y Xu, DL Yang, XC Ke, YN Lin, XF Zhang, Z Zheng, ZQ Luo, ZR Chen, YD Ding, CH Zheng, Y Li, XD Peng, DQ Li, Y Wei, M Liu, SW Yu, YH Qu, BM Jiang, WH Zhou, YJ Zhao, XS Yuan, ZY Guo, Y Xu, XP Shi, XB Ge, JB Fu, GS Bai, F Fang, WY Shou, XL Yang, XJ Wang, JA Sun, YX Lu, QH Zhang, RY Zhu, JH Xu, YZ Fan, ZC Li, TC Wu, C Jaramillo, N Vallejo, GS Botia, DCL Lopez, RB De Salazar, DIM Bonfanti, AJC Higuera, JD Silva, SIB Lozada, HJG Arroyo, JAC Mendoza, JLA Ruiz, RLF Jatin, FGM Herazo, AS Parada, JC Triana, MAU Strozzi, M Car, S Milicic, D Bencic, ML Pintaric, H Prvulovic, D Sikic, J Persic, V Mileta, D Stambuk, K Zdravko, B Tomulic, V Krstulovic, SM Starcevic, B Spinar, J Horak, D Stasek, J Alan, D Machova, V Linhart, A Novotny, V Kaucak, V Rokyta, R Naplava, R Coufal, Z Adamkova, V Podpera, I Zizka, J Motovska, Z Marusincova, I Svab, P Ostadal, P Heinc, P Kuchar, J Povolny, P Matuska, J Raungaard, B Clemmensen, P Bang, LE May, O Bottcher, M Hove, JD Frost, L Gislason, G Larsen, J Johansen, PB Hald, F Jeppesen, J Nielsen, T Kristensen, KS Walichiewicz, PM Lomholdt, JD Klausen, IC Nielsen, PK Davidsen, F Videbaek, L Soots, M Vahula, V Hedman, A Soopold, U Martsin, K Kristjan, A Taskinen, MR Porthan, K Airaksinen, JK Juonala, M Kiviniemi, T Vikman, S Posio, P Taurio, J Huikuri, H Kaikkonen, K Coste, P Ferrari, E Morel, O Montalescot, G Barone-Rochette, G Mansourati, J Cottin, Y Leclercq, F Belhassane, A Delarche, N Boccara, F Paganelli, F Clerc, J Schiele, F Aboyans, V Probst, V Berland, J Lefevre, T Citron, B Khintibidze, I Shaburishvili, T Pagava, Z Ghlonti, R Lominadze, Z Khabeishvili, G Hemetsberger, R Rauch-Krohnert, U Stratmann, M Appel, KF Schmidt, E Omran, H Stellbrink, C Dorsel, T Lianopoulos, E Marx, R Zirlik, A Schellenberg, D Heitzer, T Laufs, U Marx, N Gielen, S Winkelmann, B Behrens, S Sydow, K Simonis, G Muenzel, T Werner, N Leggewie, S Bocker, D Braun-Dullaeus, R Toursarkissian, N Jeserich, M Weissbrodt, M Schaeufele, T Weil, J Voller, H Waltenberger, J Natour, M Schmitt, S Steiner, S Heidenreich, L Gremmler, U Killat, H Rieker, W Patsilinakos, S Kartalis, A Manolis, A Sionis, D Liberopoulos, E Skoumas, I Athyros, V Vardas, P Parthenakis, F Alexopoulos, D Hahalis, G Lekakis, J Hatzitolios, A Ovando, SRF Valdovinos, PCM Benecke, JLA De Leon, ERR Yan, BPY Siu, DCW Turi, T Merkely, B Kiss, RG Ungi, I Lupkovics, G Nagy, L Katona, A Edes, I Muller, G Horvath, I Kapin, T Falukozy, J Kumbla, M Sandhu, M Annam, S Proddutur, NR Premchand, RK Mahajan, A Abhyanakar, AD Kerkar, P Govinda, RA Oomman, A Sinha, D Patil, SN Kahali, D Sawhney, J Joshi, AB Chaudhary, S Harkut, P Guha, S Porwal, S Jujjuru, S Pothineni, RB Monteiro, MR Khan, A Iyengar, SS Grewal, JS Chopda, M Fulwani, MC Patange, A Chopra, VK Goyal, NK Shinde, R Manakshe, GV Patki, N Sethi, S Munusamy, V Karna, S Adhyapak, S Pandurangi, U Mathur, R Kalashetti, S Bhagwat, A Raghuraman, B Yerra, SK Bhansali, P Borse, R Das, S Abdullakutty, J Saathe, S Abdullkutty, J Sathe, S Palimkar, P Atar, S Shechter, M Mosseri, M Arbel, Y Lotan, C Rosenschein, U Katz, A Henkin, Y Francis, A Klutstein, M Nikolsky, E Turgeman, Y Halabi, M Kornowski, R Jonas, M Amir, O Rozenman, Y Fuchs, S Hussein, O Gavish, D Vered, Z Caraco, Y Elias, M Tov, N Lishner, M Elias, N Piovaccari, G De Pellegrin, A Guardigli, G Licciardello, G Auguadro, C Cuccia, C Salvioni, A Musumeci, G Calabro, P Novo, S Faggiano, P De Cesare, NB Berti, S Cavallini, C Puccioni, E Galvani, M Tespili, M Piatti, P Palvarini, M De Luca, G Violini, R De Leo, A Filardi, PP Ferratini, M Ricca, V Dai, K Kamiya, H Ando, K Takeda, Y Morino, Y Hata, Y Kimura, K Kishi, K Michishita, I Uehara, H Higashikata, T Hirayama, A Hirooka, K Sakagami, S Taguchi, S Koike, A Fujinaga, H Koba, S Kozuma, K Kawasaki, T Ono, Y Shimizu, M Katsuda, Y Wada, A Shinke, T Kimura, T Ako, J Fujii, K Takahashi, T Sakamoto, T Furukawa, Y Sugino, H Mano, T Utsu, N Ito, K Haraguchi, T Ueda, Y Nishibe, A Masutani, M Fujimoto, K Yoon, JH Kim, SH Park, HS Chae, IH Kim, MH Jeong, MH Rha, S Kim, C Hong, T Tahk, SJ Kim, Y Busmane, A Pontaga, N Strelnieks, A Mintale, I Sime, I Petrulioniene, Z Kavaliauskiene, R Jurgaitiene, R Sakalyte, G Slapikas, R Norkiene, S Misonis, N Kibarskis, A Kubilius, R Bojovski, S Kedev, S Lozance, N Kjovkaroski, A Doncovska, S Ong, TK Kasim, S Maskon, O Kandasamy, B Yusoff, K Liew, HB Mohamed, WMIW Castillo, AG Calvillo, JC Campos, PF Fragoso, JCN Llamas, EAB Gamba, MAA Madrigal, JC Salas, LGG Rosas, EL Diaz, BG Vazquez, ES Ackar, AN Esperon, GAL Sanchez, CRM De Leon, MG Otero, RS Salmon, GF Rios, JA Ruiz, JAG Breedveld, RW Hoogslag, PAM Suryapranata, H Oomen, A Wiersma, JJ Van Der Wal, RMA Van Huysduynen-Monraats, PSH Karalis, I Verdel, GJE Brueren, BR Troquay, RPT Viergever, EP Al-Windy, NYY Bartels, GL Cornel, JH Hermans, WRM Herrman, JPR Bos, RJ Groutars, RGEJ Van Der Zwaan, CC Kaplan, R Ronner, E Groenemeijer, BE Bronzwaer, PNA Liem, AAH Rensing, BJWM Bokern, MJJA Nijmeijer, R Hersbach, FMRJ Willems, FF Gosselink, ATM Elliott, J Wilkins, G Fisher, R Scott, D Hart, H Stewart, R Harding, S Ternouth, I Fisher, N Aitken, D Anscombe, R Davidson, L Tomala, T Nygard, O Sparby, JA Andersen, K Gullestad, L Jortveit, J Munk, PS Singsaas, EG Halvorsen, S Hurtig, U Flores, RMC Ticona, JRC Velasquez, JRD Miguel, SAN Perez, ESS Chambilla, JMC Ayala, CAC Leon, RPC Gonzales, RJV Zuniga, JDH Cosavalente, LAC Mannucci, JEB Landeo, JH Navarro, NCL Concha, YMR Chavez, VER Hernandez, HAA Nunez, CAZ Ramos, WM Ferrolino, A Sy, RAG Tirador, L Sy, RG Matiga, G Coching, RM Bernan, A Rogelio, G Morales, DD Tan, E Sulit, DJ Wlodarczak, A Jaworska, K Skonieczny, G Pawlowicz, L Wojewod, P Busz-Papiez, B Bednarski, J Goch, A Staneta, P Dulak, E Budaj, A Saminsk, K Krasowski, W Sudnik, W Zurakowski, A Skorski, M Lysek, R Miklaszewicz, B Kubica, J Lipko, JA Kostarska-Srokosz, E Piepiorka, M Drzewiecka, A Sciborski, R Stasiewski, A Blicharski, T Bystryk, L Szpajer, M Korol, M Czerski, T Mirek-Bryniarska, E Gniot, J Lubinski, A Gorny, J Franek, E Raczak, G Szwed, H Monteiro, P Bastos, JM Pereira, HH Martins, D Morais, J Seixo, F Mendonca, C Botelho, A Minescu, B Istratoaie, O Tesloianu, DN Dorobantu, M Cristian, G Podoleanu, CGC Constantinescu, MCA Bengus, CM Militaru, C Rosu, D Parepa, IR Matei, AV Alexandru, TM Coman, I Cioranu, RS Dimulescu, D Shvarts, Y Orlikova, O Kobalava, Z Barbarash, OL Markov, V Lyamina, N Gordienko, A Zrazhevsky, K Vishnevsky, AY Gurevich, V Stryuk, R Lomakin, NV Bokarev, I Shalaev, S Khaisheva, L Chizhov, P Viktorova, I Osokina, N Akatova, E Chumakova, G Libov, I Voevoda, MI Tretyakova, TV Baranov, E Shustov, S Yakushin, S Gordeev, I Khasanov, N Reshetko, O Sotnikova, T Molchanova, O Nikolaev, K Gapon, L Baranova, E Shogenov, Z Kosmachova, E Karpov, Y Povzun, A Egorova, L Tyrenko, VV Ivanov, IG Kanorsky, S Simic, D Ivanovic, N Davidovic, G Tasic, N Asanin, MR Stojic, S Apostolovic, SR Ilic, S Putnikovic, B Stankovic, A Arandjelovic, A Radovanovic, S Ristic, AD Balinovac, J Dincic, DV Seferovic, P Dodic, S Dimkovic, S Poh, KK Ong, HY Micko, K Nociar, J Pella, D Fulop, P Hranai, M Palka, J Mazur, J Majercak, I Dzupina, A Fazekas, F Gonsorcik, J Bugan, V Selecky, J Kamensky, G Strbova, J Smik, R Dukat, A Olexa, P Zuran, I Poklukar, J Suligoj, NC Cevc, M Cyster, HP Ranjith, N Corbett, C Bayat, J Makotoko, EM Kapp, IE Basson, MMD Lottering, H Van Zyl, LJ Sebastian, PJ Pillay, T Saaiman, JA Commerford, PJ Cassimjee, S Ebrahim, IO Sarvan, M Mynhardt, JH Reuter, H Moodley, R Vida, M Fillat, ARC Peris, VB Jimenez, FF Marin, F Fernandez, JMC Gil-Extremera, B Diz, FW Garcia-Dorado, D Iniguez, A Fernandez, JT Gonzalez-Juanatey, JR Portales, JF Murillo, FC Pericas, LM Zamorano, JL Martin, MD Cortada, JB Martin, JJA Fernandez, JRD Fernandez, JFD Lledo, JAG Sales, JC Rodriguez, JB Tragant, GG Benedicto, A Gonzalez-Juanatey, C Potau, MC Perez, IP De La Tassa, CM Rincon, PLO Recena, JB Escudier, JM Payeras, AC Orcajo, NA Valdivielso, P Constantine, G Haniffa, R Tissera, N Amarasekera, S Fernando, N Jayawardena, J Santharaj, W Ekanayaka, R Mendis, S Senaratne, V Mayurathan, G Sirisena, T Rajapaksha, A Herath, JI Amarasena, N Berglund, S Rasmanis, G Witt, N Mourtzinis, G Nicol, P Hansen, O Romeo, S Jensen, SA Torstensson, I Ahremark, U Sundelin, T Moccetti, T Muller, C Mach, F Binder, R Tsai, WC Ueng, KC Lai, WT Liu, ME Hwang, JJ Yin, WH Hsieh, IC Kuo, JY Huang, TY Fang, CY Kaewsuwanna, P Soonfuang, W Jintapakorn, W Sukonthasarn, A Wongpraparut, N Sastravaha, K Sansanayudh, N Kehasukcharoen, W Piyayotai, D Chotnoparatpat, P Camsari, A Kultursay, H Mutlu, B Ersanli, M Demirtas, M Kirma, C Ural, E Koldas, L Karpenko, O Prokhorov, A Vakaluyk, I Myshanych, H Reshotko, D Batushkin, V Rudenko, L Kovalskyi, I Kushnir, M Tseluyko, V Mostovoy, Y Stanislavchuk, M Kyiak, Y Karpenko, Y Malynovsky, Y Klantsa, A Kutniy, O Amosova, E Tashchuk, V Leshchuk, O Rishko, M Kopytsya, M Yagensky, A Vatutin, M Bagriy, A Barna, OM Ushakov, O Dzyak, G Goloborodko, B Rudenko, A Zheleznyy, V Trevelyan, J Zaman, A Lee, K Moriarty, A Aggarwal, RK Clifford, P Wong, YK Iqbal, SM Subkovas, E Braganza, D Sarkar, D Storey, R Griffiths, H Mcclure, S Muthusamy, R Kurian, J Levy, T Barr, C Kadr, H Gerber, R Simaitis, A Soran, H Mathur, A Brodison, A Oliver, R Mudawi, T Reynolds, T Sharman, D Butler, R Wilkinson, P Lip, GYH Halcox, J Vardi, G Baldari, D Brabham, D Treasure, C Dahl, C Palmer, B Wiseman, A Puri, S Mohart, AE Ince, C Flores, E Wright, S Cheng, SC Rosenberg, M Rogers, W Kosinski, E Forgosh, L Waltman, J Khan, M Shoukfeh, M Dagher, G Lieber, I Kumar, P East, C Krichmar, P White, L Knickelbine, T Haldis, T Gillespie, E Suh, D Arif, I Akhter, F Carlson, E D'Urso, M El-Ahdab, F Nelson, W Harris, B Cohen, S Carter, L Sabatino, K Haddad, T Malik, A Rao, S Mulkay, A Jovin, I Klancke, K Malhotra, V Devarapalli, SK Koren, M Chandna, H Dodds, G Janik, M Moran, J Sumner, A Kobayashi, J Davis, W Yazdani, S Pasquini, J Thakkar, M Vedere, A Leimbach, W Rider, J Singh, N Shah, AV Janosik, D Pepine, C Berman, B Gelormini, J Daniels, C Keating, F Kondo, NI Shetty, S Waider, W Takata, T Abu-Fadel, M Shah, V Aggarwal, R Izzo, M Kumar, A Hattler, B Link, C Bortnick, A Kinzfogl, G Ghitis, A Larry, J Teufel, E Kuhlman, P Mclaurin, B Zhang, WW Thew, S Abbas, J White, M Ranadive, N Gring, C Henderson, D Schuchard, T Farhat, N Kline, G Mahal, S Whitaker, J Speirs, S Andersen, R Daboul, N Horwitz, P Ponce, G Jafar, Z Mcgarvey, J Panchal, V Voyce, S Blok, T Sheldon, W Azizad, MM Schmalfuss, C Picone, M Herzog, W Lindsey, J Nowins, R Lepor, N El Shahawy, M Weintraub, H Irimpen, A May, W Galski, T Chu, A Mody, F Hodes, Z Rose, G Fairlamb, J Lambert, C Raisinghani, A Abbate, A King, M Carey, C Gerber, J Younis, L Park, H Vidovich, M Knutson, T Friedman, D Chaleff, F Loussararian, A Rozeman, P Kimmelstiel, C Silver, K Foster, M Tonnessen, G Amlani, M Wali, A Malozzi, C Wattanakit, K O'Donnell, PJ Singal, D Jaffrani, N Banuru, S Fisher, D Xenakis, M Perlmutter, N Bhagwat, R Strader, J Akyea-Djamson, A Labroo, A Marais, HJ Claxton, E Berk, M Rossi, P Joshi, P Khaira, AS Kumkumian, G Lupovitch, S Purow, J Welka, S Hoffman, D Fischer, S Soroka, E Eagerton, D Pancholy, S Ray, M Farrar, M Pollock, S French, WJ Diamantis, S Gimple, L Neustel, M Schwartz, S Pereira, E Spriggs, D Strain, J Vo, A Chane, M Hall, J Vijay, N Lotun, K Lester, FM Nahhas, A Pope, T Nager, P Vohra, R Bashir, R Ahmed, H Berlowitz, M Fishberg, R Barrucco, R Yang, E Radin, M Sporn, D Eisenberg, S Landzberg, J Mcgough, M Turk, S Schwartz, M Sundram, PS Jain, D Zainea, M Bayron, C Karlsberg, R Lui, H Keen, W Westerhausen, D Khurana, S Agarwal, H Birchem, J Penny, W Chang, M Murphy, S Schifferdecker, B Gilbert, JM Chalavarya, G Eaton, C Schmedtje, JF Christenson, S Denham, D Macdonell, A Gibson, P Rahman, A Al Joundi, T Conrad, G Kotha, P Love, M Giesler, G Rubenstein, H Akright, L Krawczyk, J Wells, T Welker, J Foster, R Gilmore, R Anderson, J Jacoby, D Gardner, G Dandillaya, R Vora, K Kostis, J Hunter, J Laxson, D Ball, E Camp, A Lopes, R Egydio, F Kawakami, A Oliveira, J Wozniak, J Matthews, A Ratky, C Valiris, J Berdan, L Hepditch, A Quintero, K Rorick, T Westbrook, M Pascual, A Rovito, C Bezault, M Drouet, E Simon, T Alsweiler, C Luyten, A Aylward, P Butters, J Griffith, L Shaw, M Hagstrom, E Grunberg, L Islam, S Bregeault, MF Bougon, N Faustino, D Fontecave, S Murphy, J Tamby, JF Verrier, M Agnetti, V Andersen, D Badreddine, E Bekkouche, M Bouancheau, C Brigui, I Brocklehurst, M Cianciarulo, J Devaul, D Domokos, S Gache, C Gobillot, C Guillou, S Healy, J Heath, M Jaiwal, G Javierre, C Labeirie, J Monier, M Morales, U Mrabti, A Mthombeni, B Okan, B Smith, L Sheller, J Sopena, S Pellan, V Benbernou, F Bengrait, N Lamoureux, M Kralova, K Scemama, M Bejuit, R Coulange, A Berthou, C Repincay, J Lorenzato, C Etienne, A Gouet, V Loizeau, V Normand, M Ourliac, A Rondel, C Adamo, A Beltran, P Barraud, P Dubois-Gache, H Halle, B Metwally, L Mourgues, M Sotty, M Vincendet, M Cotruta, R Zhu, CY Fournie-Lloret, D Morrello, C Perthuis, A Picault, P Zobouyan, I |
| author_role | author |
| collection | r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí |
| description | BACKGROUND Patients with acute coronary syndrome (ACS) and concomitant noncoronary atherosclerosis have a high risk of major adverse cardiovascular events (MACEs) and death. The impact of lipid lowering by proprotein convertase subtilisin-kexin type 9 inhibition in such patients is undetermined. OBJECTIVES This pre-specified analysis from ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) determined whether polyvascular disease influenced risks of MACEs and death and their modification by alirocumab in patients with recent ACS and dyslipidemia despite intensive statin therapy. METHODS Patients were randomized to alirocumab or placebo 1 to 12 months after ACS. The primary MACEs endpoint was the composite of coronary heart disease death, nonfatal myocardial infarction, fatal or nonfatal ischemic stroke, or unstable angina requiring hospitalization. All-cause death was a secondary endpoint. RESULTS Median follow-up was 2.8 years. Of 18,924 patients, 17,370 had monovascular (coronary) disease, 1,405 had polyvascular disease in 2 beds (coronary and peripheral artery or cerebrovascular), and 149 had polyvascular disease in 3 beds (coronary, peripheral artery, cerebrovascular). With placebo, the incidence of MACEs by respective vascular categories was 10.0%, 22.2%, and 39.7%. With alirocumab, the corresponding absolute risk reduction was 1.4% (95% confidence interval [CI]: 0.6% to 2.3%), 1.9% (95% CI: -2.4% to 6.2%), and 13.0% (95% CI: -2.0% to 28.0%). With placebo, the incidence of death by respective vascular categories was 3.5%, 10.0%, and 21.8%; the absolute risk reduction with alirocumab was 0.4% (95% CI: -0.1% to 1.0%), 1.3% (95% CI: -1.8% to 4.3%), and 16.2% (95% CI: 5.5% to 26.8%). CONCLUSIONS In patients with recent ACS and dyslipidemia despite intensive statin therapy, polyvascular disease is associated with high risks of MACEs and death. The large absolute reductions in those risks with alirocumab are a potential benefit for these patients. (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab [ODYSSEY OUTCOMES]: NCT01663402) (C) 2019 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_1a15bcc0fc418cef70e8ff5deeb8672b |
| institution | Institut d'Investigació i Innovació Parc Taulí (I3PT) |
| instname_str | Institut d'Investigació i Innovació Parc Taulí (I3PT) |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:i3pt.fundanetsuite.com:p2904 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher | ELSEVIER SCIENCE INC |
| publisherStr | ELSEVIER SCIENCE INC |
| reponame_str | r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí |
| spelling | Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial Jukema, JW Szarek, M Zijlstra, LE de Silva, HA Bhatt, DL Bittner, VA Diaz, R Edelberg, JM Hanotin, C Harrington, RA Moryusef, A White, HD Zeiher, AM Schwartz, GG Steg, PG Tricoci, P Mahaffey, KW Lecorps, G Pordy, R Sasiela, WJ Drexel, H Sinnaeve, P Dilic, M Gotcheva, NN Goodman, SG Prieto, JC Yong, H Lopez-Jaramillo, P Pecin, I Reiner, Z Poulsen, SH Viigimaa, M Nieminen, MS Danchin, N Chumburidze, V Tse, HF Xavier, D Zahger, D Valgimigli, M Kim, HS Erglis, A Laucevicius, A Lopez, R Lopez, GAR Alings, M Chua, T Murin, J Fras, Z Dalby, AJ Tunon, J De Silva, HA Chiang, CE Sritara, P Guneri, S Parkhomenko, A Ray, KK Moriarty, PM Roe, MT Chaitman, B Kelsey, SF Olsson, AG Rouleau, JL Simoons, ML Alexander, K Meloni, C Rosenson, R Sijbrands, EJG Alexander, JH Armaganijan, L Bagai, A Bahit, MC Brennan, JM Clifton, S DeVore, AD Deloatch, S Dickey, S Dombrowski, K Ducrocq, G Eapen, Z Endsley, P Eppinger, A Harrison, RW Hess, CN Hlatky, MA Jordan, JD Knowles, JW Kolls, BJ Kong, DF Leonardi, S Lillis, L Maron, DJ Marcus, J Mathews, R Mehta, RH Mentz, RJ Moreira, HG Patel, CB Pereira, SB Perkins, L Povsic, TJ Puymirat, E Jones, WS Shah, BR Sherwood, MW Stringfellow, K Sujjavanich, D Toma, M Van Diepen, SFP Wilson, MD Yan, ATK Lopes, RD Trotter, C Schiavi, LB Garrido, M Alvarisqueta, AF Sassone, SA Bordonava, AP De Lima, AEA Schmidberg, JM Duronto, EA Caruso, OC Novaretto, LP Hominal, MA Montana, OR Caccavo, A Vilamajo, OAG Lorenzatti, AJ Cartasegna, LR Paterlini, GA Mackinnon, IJ Caime, GD Amuchastegui, M Salomone, R Codutti, OR Jure, HO Bono, JOE Hrabar, AD Vallejos, JA Guerrero, RAA Novoa, F Patocchi, CA Zaidman, CJ Giuliano, ME Dran, RD Vico, ML Carnero, GS Guzman, PN Allende, JCM Brasca, DFG Labarta, MHB Nani, S Blumberg, EDS Colombo, HR Liberman, A Luciardi, HL Waisman, GD Berli, MA Duran, ROG Cestari, HG Luquez, HA Giordano, JA Saavedra, SS Zapata, G Costamagna, O Llois, S Waites, JH Collins, N Soward, A Aylward, PE Hii, CLS Shaw, J Arstall, MA Horowitz, J Rogers, JF Colquhoun, D Flores, REO Roberts-Thomson, P Raffel, O Lehman, SJ Aroney, C Coverdale, SGM Garrahy, PJ Starmer, G Sader, M Carroll, PA Dick, R Zweiker, R Hoppe, U Huber, K Berger, R Weidinger, F Faes, D Hermans, K Pirenne, B Leone, A Hoffer, E Vrolix, MCM De Wolf, L Wollaert, B Castadot, M Dujardin, K Beauloye, C Vervoort, G Striekwold, H Convens, C Roosen, J Barbato, E Claeys, M Cools, F Terzic, I Barakovic, F Midzic, Z Pojskic, B Fazlibegovic, E Durak-Nalbantic, A Vulic, D Muslibegovic, A Goronja, B Reis, G Sousa, L Nicolau, JC Giorgeto, FE Silva, RP Maia, LN Rech, R Rossi, PRF Cerqueira, MJAG Duda, N Kalil, R Kormann, A Abrantes, JAM Pimentel, P Soggia, AP de Santos, MON Neuenschwander, F Bodanese, LC Michalaros, YL Eliaschewitz, FG Vidotti, MH Leaes, PE Botelho, RV Kaiser, S Manenti, ERFF Precoma, DB Jorge, JCM Silva, PGMD Silveira, JA Saporito, W Marin, JA Feitosa, GS Ritt, LEF de Souza, JA Costa, F Souza, WKSB Reis, HJL Machado, L Ayoub, JCA Todorov, GV Nikolov, FP Velcheva, ES Tzekova, ML Benov, HO Petranov, SL Tumbev, HS Shehova-Yankova, NS Markov, DT Raev, DH Mollov, MN Kichukov, KN Ilieva-Pandeva, KA Ivanova, R Mincheva, VM Lazov, PV Dimov, BI Senaratne, M Stone, J Kornder, J Pearce, S Dion, D Savard, D Pesant, Y Pandey, A Robinson, S Gosselin, G Vizel, S Hoag, G Bourgeois, R Morisset, A Sabbah, E Sussex, B Kouz, S MacDonald, P Diaz, A Michaud, N Fell, D Leung, R Vuurmans, T Lai, C Nigro, F Davies, R Nogareda, G Vijayaraghavan, R Ducas, J Lepage, S Mehta, S Cha, J Dupuis, R Fong, P Rodes-Cabau, J Fadlallah, H Cleveland, D Huynh, T Bata, I Hameed, A Pincetti, C Potthoff, S Acevedo, M Aguirre, A Vejar, M Yanez, M Araneda, G Fernandez, M Perez, L Varleta, P Florenzano, F Huidobro, L Raffo, CA Olivares, C Nahuelpan, L Montecinos, H Chen, JY Dong, YG Huang, WJ Wang, JZ Huang, SA Yao, ZH Li, X Cui, L Lin, WH Sun, YM Wang, JF Li, JP Zhang, XL Zhu, H Chen, D Huang, L Dong, SH Su, GH Xu, BA Su, X Cheng, XS Lin, JX Zong, WX Li, HM Feng, Y Xu, DL Yang, XC Ke, YN Lin, XF Zhang, Z Zheng, ZQ Luo, ZR Chen, YD Ding, CH Zheng, Y Li, XD Peng, DQ Li, Y Wei, M Liu, SW Yu, YH Qu, BM Jiang, WH Zhou, YJ Zhao, XS Yuan, ZY Guo, Y Xu, XP Shi, XB Ge, JB Fu, GS Bai, F Fang, WY Shou, XL Yang, XJ Wang, JA Sun, YX Lu, QH Zhang, RY Zhu, JH Xu, YZ Fan, ZC Li, TC Wu, C Jaramillo, N Vallejo, GS Botia, DCL Lopez, RB De Salazar, DIM Bonfanti, AJC Higuera, JD Silva, SIB Lozada, HJG Arroyo, JAC Mendoza, JLA Ruiz, RLF Jatin, FGM Herazo, AS Parada, JC Triana, MAU Strozzi, M Car, S Milicic, D Bencic, ML Pintaric, H Prvulovic, D Sikic, J Persic, V Mileta, D Stambuk, K Zdravko, B Tomulic, V Krstulovic, SM Starcevic, B Spinar, J Horak, D Stasek, J Alan, D Machova, V Linhart, A Novotny, V Kaucak, V Rokyta, R Naplava, R Coufal, Z Adamkova, V Podpera, I Zizka, J Motovska, Z Marusincova, I Svab, P Ostadal, P Heinc, P Kuchar, J Povolny, P Matuska, J Raungaard, B Clemmensen, P Bang, LE May, O Bottcher, M Hove, JD Frost, L Gislason, G Larsen, J Johansen, PB Hald, F Jeppesen, J Nielsen, T Kristensen, KS Walichiewicz, PM Lomholdt, JD Klausen, IC Nielsen, PK Davidsen, F Videbaek, L Soots, M Vahula, V Hedman, A Soopold, U Martsin, K Kristjan, A Taskinen, MR Porthan, K Airaksinen, JK Juonala, M Kiviniemi, T Vikman, S Posio, P Taurio, J Huikuri, H Kaikkonen, K Coste, P Ferrari, E Morel, O Montalescot, G Barone-Rochette, G Mansourati, J Cottin, Y Leclercq, F Belhassane, A Delarche, N Boccara, F Paganelli, F Clerc, J Schiele, F Aboyans, V Probst, V Berland, J Lefevre, T Citron, B Khintibidze, I Shaburishvili, T Pagava, Z Ghlonti, R Lominadze, Z Khabeishvili, G Hemetsberger, R Rauch-Krohnert, U Stratmann, M Appel, KF Schmidt, E Omran, H Stellbrink, C Dorsel, T Lianopoulos, E Marx, R Zirlik, A Schellenberg, D Heitzer, T Laufs, U Marx, N Gielen, S Winkelmann, B Behrens, S Sydow, K Simonis, G Muenzel, T Werner, N Leggewie, S Bocker, D Braun-Dullaeus, R Toursarkissian, N Jeserich, M Weissbrodt, M Schaeufele, T Weil, J Voller, H Waltenberger, J Natour, M Schmitt, S Steiner, S Heidenreich, L Gremmler, U Killat, H Rieker, W Patsilinakos, S Kartalis, A Manolis, A Sionis, D Liberopoulos, E Skoumas, I Athyros, V Vardas, P Parthenakis, F Alexopoulos, D Hahalis, G Lekakis, J Hatzitolios, A Ovando, SRF Valdovinos, PCM Benecke, JLA De Leon, ERR Yan, BPY Siu, DCW Turi, T Merkely, B Kiss, RG Ungi, I Lupkovics, G Nagy, L Katona, A Edes, I Muller, G Horvath, I Kapin, T Falukozy, J Kumbla, M Sandhu, M Annam, S Proddutur, NR Premchand, RK Mahajan, A Abhyanakar, AD Kerkar, P Govinda, RA Oomman, A Sinha, D Patil, SN Kahali, D Sawhney, J Joshi, AB Chaudhary, S Harkut, P Guha, S Porwal, S Jujjuru, S Pothineni, RB Monteiro, MR Khan, A Iyengar, SS Grewal, JS Chopda, M Fulwani, MC Patange, A Chopra, VK Goyal, NK Shinde, R Manakshe, GV Patki, N Sethi, S Munusamy, V Karna, S Adhyapak, S Pandurangi, U Mathur, R Kalashetti, S Bhagwat, A Raghuraman, B Yerra, SK Bhansali, P Borse, R Das, S Abdullakutty, J Saathe, S Abdullkutty, J Sathe, S Palimkar, P Atar, S Shechter, M Mosseri, M Arbel, Y Lotan, C Rosenschein, U Katz, A Henkin, Y Francis, A Klutstein, M Nikolsky, E Turgeman, Y Halabi, M Kornowski, R Jonas, M Amir, O Rozenman, Y Fuchs, S Hussein, O Gavish, D Vered, Z Caraco, Y Elias, M Tov, N Lishner, M Elias, N Piovaccari, G De Pellegrin, A Guardigli, G Licciardello, G Auguadro, C Cuccia, C Salvioni, A Musumeci, G Calabro, P Novo, S Faggiano, P De Cesare, NB Berti, S Cavallini, C Puccioni, E Galvani, M Tespili, M Piatti, P Palvarini, M De Luca, G Violini, R De Leo, A Filardi, PP Ferratini, M Ricca, V Dai, K Kamiya, H Ando, K Takeda, Y Morino, Y Hata, Y Kimura, K Kishi, K Michishita, I Uehara, H Higashikata, T Hirayama, A Hirooka, K Sakagami, S Taguchi, S Koike, A Fujinaga, H Koba, S Kozuma, K Kawasaki, T Ono, Y Shimizu, M Katsuda, Y Wada, A Shinke, T Kimura, T Ako, J Fujii, K Takahashi, T Sakamoto, T Furukawa, Y Sugino, H Mano, T Utsu, N Ito, K Haraguchi, T Ueda, Y Nishibe, A Masutani, M Fujimoto, K Yoon, JH Kim, SH Park, HS Chae, IH Kim, MH Jeong, MH Rha, S Kim, C Hong, T Tahk, SJ Kim, Y Busmane, A Pontaga, N Strelnieks, A Mintale, I Sime, I Petrulioniene, Z Kavaliauskiene, R Jurgaitiene, R Sakalyte, G Slapikas, R Norkiene, S Misonis, N Kibarskis, A Kubilius, R Bojovski, S Kedev, S Lozance, N Kjovkaroski, A Doncovska, S Ong, TK Kasim, S Maskon, O Kandasamy, B Yusoff, K Liew, HB Mohamed, WMIW Castillo, AG Calvillo, JC Campos, PF Fragoso, JCN Llamas, EAB Gamba, MAA Madrigal, JC Salas, LGG Rosas, EL Diaz, BG Vazquez, ES Ackar, AN Esperon, GAL Sanchez, CRM De Leon, MG Otero, RS Salmon, GF Rios, JA Ruiz, JAG Breedveld, RW Hoogslag, PAM Suryapranata, H Oomen, A Wiersma, JJ Van Der Wal, RMA Van Huysduynen-Monraats, PSH Karalis, I Verdel, GJE Brueren, BR Troquay, RPT Viergever, EP Al-Windy, NYY Bartels, GL Cornel, JH Hermans, WRM Herrman, JPR Bos, RJ Groutars, RGEJ Van Der Zwaan, CC Kaplan, R Ronner, E Groenemeijer, BE Bronzwaer, PNA Liem, AAH Rensing, BJWM Bokern, MJJA Nijmeijer, R Hersbach, FMRJ Willems, FF Gosselink, ATM Elliott, J Wilkins, G Fisher, R Scott, D Hart, H Stewart, R Harding, S Ternouth, I Fisher, N Aitken, D Anscombe, R Davidson, L Tomala, T Nygard, O Sparby, JA Andersen, K Gullestad, L Jortveit, J Munk, PS Singsaas, EG Halvorsen, S Hurtig, U Flores, RMC Ticona, JRC Velasquez, JRD Miguel, SAN Perez, ESS Chambilla, JMC Ayala, CAC Leon, RPC Gonzales, RJV Zuniga, JDH Cosavalente, LAC Mannucci, JEB Landeo, JH Navarro, NCL Concha, YMR Chavez, VER Hernandez, HAA Nunez, CAZ Ramos, WM Ferrolino, A Sy, RAG Tirador, L Sy, RG Matiga, G Coching, RM Bernan, A Rogelio, G Morales, DD Tan, E Sulit, DJ Wlodarczak, A Jaworska, K Skonieczny, G Pawlowicz, L Wojewod, P Busz-Papiez, B Bednarski, J Goch, A Staneta, P Dulak, E Budaj, A Saminsk, K Krasowski, W Sudnik, W Zurakowski, A Skorski, M Lysek, R Miklaszewicz, B Kubica, J Lipko, JA Kostarska-Srokosz, E Piepiorka, M Drzewiecka, A Sciborski, R Stasiewski, A Blicharski, T Bystryk, L Szpajer, M Korol, M Czerski, T Mirek-Bryniarska, E Gniot, J Lubinski, A Gorny, J Franek, E Raczak, G Szwed, H Monteiro, P Bastos, JM Pereira, HH Martins, D Morais, J Seixo, F Mendonca, C Botelho, A Minescu, B Istratoaie, O Tesloianu, DN Dorobantu, M Cristian, G Podoleanu, CGC Constantinescu, MCA Bengus, CM Militaru, C Rosu, D Parepa, IR Matei, AV Alexandru, TM Coman, I Cioranu, RS Dimulescu, D Shvarts, Y Orlikova, O Kobalava, Z Barbarash, OL Markov, V Lyamina, N Gordienko, A Zrazhevsky, K Vishnevsky, AY Gurevich, V Stryuk, R Lomakin, NV Bokarev, I Shalaev, S Khaisheva, L Chizhov, P Viktorova, I Osokina, N Akatova, E Chumakova, G Libov, I Voevoda, MI Tretyakova, TV Baranov, E Shustov, S Yakushin, S Gordeev, I Khasanov, N Reshetko, O Sotnikova, T Molchanova, O Nikolaev, K Gapon, L Baranova, E Shogenov, Z Kosmachova, E Karpov, Y Povzun, A Egorova, L Tyrenko, VV Ivanov, IG Kanorsky, S Simic, D Ivanovic, N Davidovic, G Tasic, N Asanin, MR Stojic, S Apostolovic, SR Ilic, S Putnikovic, B Stankovic, A Arandjelovic, A Radovanovic, S Ristic, AD Balinovac, J Dincic, DV Seferovic, P Dodic, S Dimkovic, S Poh, KK Ong, HY Micko, K Nociar, J Pella, D Fulop, P Hranai, M Palka, J Mazur, J Majercak, I Dzupina, A Fazekas, F Gonsorcik, J Bugan, V Selecky, J Kamensky, G Strbova, J Smik, R Dukat, A Olexa, P Zuran, I Poklukar, J Suligoj, NC Cevc, M Cyster, HP Ranjith, N Corbett, C Bayat, J Makotoko, EM Kapp, IE Basson, MMD Lottering, H Van Zyl, LJ Sebastian, PJ Pillay, T Saaiman, JA Commerford, PJ Cassimjee, S Ebrahim, IO Sarvan, M Mynhardt, JH Reuter, H Moodley, R Vida, M Fillat, ARC Peris, VB Jimenez, FF Marin, F Fernandez, JMC Gil-Extremera, B Diz, FW Garcia-Dorado, D Iniguez, A Fernandez, JT Gonzalez-Juanatey, JR Portales, JF Murillo, FC Pericas, LM Zamorano, JL Martin, MD Cortada, JB Martin, JJA Fernandez, JRD Fernandez, JFD Lledo, JAG Sales, JC Rodriguez, JB Tragant, GG Benedicto, A Gonzalez-Juanatey, C Potau, MC Perez, IP De La Tassa, CM Rincon, PLO Recena, JB Escudier, JM Payeras, AC Orcajo, NA Valdivielso, P Constantine, G Haniffa, R Tissera, N Amarasekera, S Fernando, N Jayawardena, J Santharaj, W Ekanayaka, R Mendis, S Senaratne, V Mayurathan, G Sirisena, T Rajapaksha, A Herath, JI Amarasena, N Berglund, S Rasmanis, G Witt, N Mourtzinis, G Nicol, P Hansen, O Romeo, S Jensen, SA Torstensson, I Ahremark, U Sundelin, T Moccetti, T Muller, C Mach, F Binder, R Tsai, WC Ueng, KC Lai, WT Liu, ME Hwang, JJ Yin, WH Hsieh, IC Kuo, JY Huang, TY Fang, CY Kaewsuwanna, P Soonfuang, W Jintapakorn, W Sukonthasarn, A Wongpraparut, N Sastravaha, K Sansanayudh, N Kehasukcharoen, W Piyayotai, D Chotnoparatpat, P Camsari, A Kultursay, H Mutlu, B Ersanli, M Demirtas, M Kirma, C Ural, E Koldas, L Karpenko, O Prokhorov, A Vakaluyk, I Myshanych, H Reshotko, D Batushkin, V Rudenko, L Kovalskyi, I Kushnir, M Tseluyko, V Mostovoy, Y Stanislavchuk, M Kyiak, Y Karpenko, Y Malynovsky, Y Klantsa, A Kutniy, O Amosova, E Tashchuk, V Leshchuk, O Rishko, M Kopytsya, M Yagensky, A Vatutin, M Bagriy, A Barna, OM Ushakov, O Dzyak, G Goloborodko, B Rudenko, A Zheleznyy, V Trevelyan, J Zaman, A Lee, K Moriarty, A Aggarwal, RK Clifford, P Wong, YK Iqbal, SM Subkovas, E Braganza, D Sarkar, D Storey, R Griffiths, H Mcclure, S Muthusamy, R Kurian, J Levy, T Barr, C Kadr, H Gerber, R Simaitis, A Soran, H Mathur, A Brodison, A Oliver, R Mudawi, T Reynolds, T Sharman, D Butler, R Wilkinson, P Lip, GYH Halcox, J Vardi, G Baldari, D Brabham, D Treasure, C Dahl, C Palmer, B Wiseman, A Puri, S Mohart, AE Ince, C Flores, E Wright, S Cheng, SC Rosenberg, M Rogers, W Kosinski, E Forgosh, L Waltman, J Khan, M Shoukfeh, M Dagher, G Lieber, I Kumar, P East, C Krichmar, P White, L Knickelbine, T Haldis, T Gillespie, E Suh, D Arif, I Akhter, F Carlson, E D'Urso, M El-Ahdab, F Nelson, W Harris, B Cohen, S Carter, L Sabatino, K Haddad, T Malik, A Rao, S Mulkay, A Jovin, I Klancke, K Malhotra, V Devarapalli, SK Koren, M Chandna, H Dodds, G Janik, M Moran, J Sumner, A Kobayashi, J Davis, W Yazdani, S Pasquini, J Thakkar, M Vedere, A Leimbach, W Rider, J Singh, N Shah, AV Janosik, D Pepine, C Berman, B Gelormini, J Daniels, C Keating, F Kondo, NI Shetty, S Waider, W Takata, T Abu-Fadel, M Shah, V Aggarwal, R Izzo, M Kumar, A Hattler, B Link, C Bortnick, A Kinzfogl, G Ghitis, A Larry, J Teufel, E Kuhlman, P Mclaurin, B Zhang, WW Thew, S Abbas, J White, M Ranadive, N Gring, C Henderson, D Schuchard, T Farhat, N Kline, G Mahal, S Whitaker, J Speirs, S Andersen, R Daboul, N Horwitz, P Ponce, G Jafar, Z Mcgarvey, J Panchal, V Voyce, S Blok, T Sheldon, W Azizad, MM Schmalfuss, C Picone, M Herzog, W Lindsey, J Nowins, R Lepor, N El Shahawy, M Weintraub, H Irimpen, A May, W Galski, T Chu, A Mody, F Hodes, Z Rose, G Fairlamb, J Lambert, C Raisinghani, A Abbate, A King, M Carey, C Gerber, J Younis, L Park, H Vidovich, M Knutson, T Friedman, D Chaleff, F Loussararian, A Rozeman, P Kimmelstiel, C Silver, K Foster, M Tonnessen, G Amlani, M Wali, A Malozzi, C Wattanakit, K O'Donnell, PJ Singal, D Jaffrani, N Banuru, S Fisher, D Xenakis, M Perlmutter, N Bhagwat, R Strader, J Akyea-Djamson, A Labroo, A Marais, HJ Claxton, E Berk, M Rossi, P Joshi, P Khaira, AS Kumkumian, G Lupovitch, S Purow, J Welka, S Hoffman, D Fischer, S Soroka, E Eagerton, D Pancholy, S Ray, M Farrar, M Pollock, S French, WJ Diamantis, S Gimple, L Neustel, M Schwartz, S Pereira, E Spriggs, D Strain, J Vo, A Chane, M Hall, J Vijay, N Lotun, K Lester, FM Nahhas, A Pope, T Nager, P Vohra, R Bashir, R Ahmed, H Berlowitz, M Fishberg, R Barrucco, R Yang, E Radin, M Sporn, D Eisenberg, S Landzberg, J Mcgough, M Turk, S Schwartz, M Sundram, PS Jain, D Zainea, M Bayron, C Karlsberg, R Lui, H Keen, W Westerhausen, D Khurana, S Agarwal, H Birchem, J Penny, W Chang, M Murphy, S Schifferdecker, B Gilbert, JM Chalavarya, G Eaton, C Schmedtje, JF Christenson, S Denham, D Macdonell, A Gibson, P Rahman, A Al Joundi, T Conrad, G Kotha, P Love, M Giesler, G Rubenstein, H Akright, L Krawczyk, J Wells, T Welker, J Foster, R Gilmore, R Anderson, J Jacoby, D Gardner, G Dandillaya, R Vora, K Kostis, J Hunter, J Laxson, D Ball, E Camp, A Lopes, R Egydio, F Kawakami, A Oliveira, J Wozniak, J Matthews, A Ratky, C Valiris, J Berdan, L Hepditch, A Quintero, K Rorick, T Westbrook, M Pascual, A Rovito, C Bezault, M Drouet, E Simon, T Alsweiler, C Luyten, A Aylward, P Butters, J Griffith, L Shaw, M Hagstrom, E Grunberg, L Islam, S Bregeault, MF Bougon, N Faustino, D Fontecave, S Murphy, J Tamby, JF Verrier, M Agnetti, V Andersen, D Badreddine, E Bekkouche, M Bouancheau, C Brigui, I Brocklehurst, M Cianciarulo, J Devaul, D Domokos, S Gache, C Gobillot, C Guillou, S Healy, J Heath, M Jaiwal, G Javierre, C Labeirie, J Monier, M Morales, U Mrabti, A Mthombeni, B Okan, B Smith, L Sheller, J Sopena, S Pellan, V Benbernou, F Bengrait, N Lamoureux, M Kralova, K Scemama, M Bejuit, R Coulange, A Berthou, C Repincay, J Lorenzato, C Etienne, A Gouet, V Loizeau, V Normand, M Ourliac, A Rondel, C Adamo, A Beltran, P Barraud, P Dubois-Gache, H Halle, B Metwally, L Mourgues, M Sotty, M Vincendet, M Cotruta, R Zhu, CY Fournie-Lloret, D Morrello, C Perthuis, A Picault, P Zobouyan, I acute coronary syndrome alirocumab cerebrovascular disease death major adverse cardiac events peripheral artery disease BACKGROUND Patients with acute coronary syndrome (ACS) and concomitant noncoronary atherosclerosis have a high risk of major adverse cardiovascular events (MACEs) and death. The impact of lipid lowering by proprotein convertase subtilisin-kexin type 9 inhibition in such patients is undetermined. OBJECTIVES This pre-specified analysis from ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) determined whether polyvascular disease influenced risks of MACEs and death and their modification by alirocumab in patients with recent ACS and dyslipidemia despite intensive statin therapy. METHODS Patients were randomized to alirocumab or placebo 1 to 12 months after ACS. The primary MACEs endpoint was the composite of coronary heart disease death, nonfatal myocardial infarction, fatal or nonfatal ischemic stroke, or unstable angina requiring hospitalization. All-cause death was a secondary endpoint. RESULTS Median follow-up was 2.8 years. Of 18,924 patients, 17,370 had monovascular (coronary) disease, 1,405 had polyvascular disease in 2 beds (coronary and peripheral artery or cerebrovascular), and 149 had polyvascular disease in 3 beds (coronary, peripheral artery, cerebrovascular). With placebo, the incidence of MACEs by respective vascular categories was 10.0%, 22.2%, and 39.7%. With alirocumab, the corresponding absolute risk reduction was 1.4% (95% confidence interval [CI]: 0.6% to 2.3%), 1.9% (95% CI: -2.4% to 6.2%), and 13.0% (95% CI: -2.0% to 28.0%). With placebo, the incidence of death by respective vascular categories was 3.5%, 10.0%, and 21.8%; the absolute risk reduction with alirocumab was 0.4% (95% CI: -0.1% to 1.0%), 1.3% (95% CI: -1.8% to 4.3%), and 16.2% (95% CI: 5.5% to 26.8%). CONCLUSIONS In patients with recent ACS and dyslipidemia despite intensive statin therapy, polyvascular disease is associated with high risks of MACEs and death. The large absolute reductions in those risks with alirocumab are a potential benefit for these patients. (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab [ODYSSEY OUTCOMES]: NCT01663402) (C) 2019 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. ELSEVIER SCIENCE INC https://i3pt.portalinvestigacion.com/publicaciones/2904 |
| spellingShingle | Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial Jukema, JW acute coronary syndrome alirocumab cerebrovascular disease death major adverse cardiac events peripheral artery disease |
| status_str | publishedVersion |
| title | Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial |
| title_full | Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial |
| title_fullStr | Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial |
| title_full_unstemmed | Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial |
| title_short | Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial |
| title_sort | Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial |
| topic | acute coronary syndrome alirocumab cerebrovascular disease death major adverse cardiac events peripheral artery disease |
| topic_facet | acute coronary syndrome alirocumab cerebrovascular disease death major adverse cardiac events peripheral artery disease |
| url | https://i3pt.portalinvestigacion.com/publicaciones/2904 |