Changes in the lipid profile 5 years after bariatric surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy
BACKGROUND: Few studies have compared mid-term results of laparoscopic Roux-en-Y gastric bypass (LRYGB) versus laparoscopic sleeve gastrectomy (LSG), and none have focused on lipid profile. OBJECTIVES: To compare LRYGB versus LSG with respect to lipid disturbance evolution and remission at mid-term...
| Autores: | ; ; ; ; ; |
|---|---|
| Tipo de documento: | Artículo |
| Estado: | Accepted version |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universitat Pompeu Fabra |
| Repositorio: | Repositorio Digital de la UPF |
| OAI Identifier: | oai:repositori.upf.edu:10230/42035 |
| Acceso en línea: | http://hdl.handle.net/10230/42035 http://dx.doi.org/10.1016/j.soard.2018.05.006 |
| Nivel de acceso: | Acceso abierto |
| Palabra clave: | Associated factors Dyslipidemia Laparoscopic Roux-en-Y gastric bypass Laparoscopic sleeve gastrectomy Bariatric surgery |
| _version_ | 1878730225473290240 |
|---|---|
| author | Climent, Elisenda |
| author2 | Benaiges Foix, David Flores Le Roux, Juana Antonia Ramón Moros, José Manuel Pedro-Botet, Juan Goday Arnó, Albert |
| author2_role | author author author author author |
| author_browse | Benaiges Foix, David Climent, Elisenda Flores Le Roux, Juana Antonia Goday Arnó, Albert Pedro-Botet, Juan Ramón Moros, José Manuel |
| author_facet | Climent, Elisenda Benaiges Foix, David Flores Le Roux, Juana Antonia Ramón Moros, José Manuel Pedro-Botet, Juan Goday Arnó, Albert |
| author_role | author |
| collection | Repositorio Digital de la UPF |
| description | BACKGROUND: Few studies have compared mid-term results of laparoscopic Roux-en-Y gastric bypass (LRYGB) versus laparoscopic sleeve gastrectomy (LSG), and none have focused on lipid profile. OBJECTIVES: To compare LRYGB versus LSG with respect to lipid disturbance evolution and remission at mid-term after bariatric surgery (BS) and to assess associated factors with the remission of lipid disturbances at 5 years. SETTING: Hospital del Mar, Barcelona, from January 2005 to January 2012. METHODS: A retrospective analysis of a nonrandomized, prospective cohort was conducted on patients undergoing BS at Hospital del Mar, Barcelona, from January 2005 to January 2012 with ≥5 years' follow-up. RESULTS: Of 259 patients, 151 (58.3%) completed the 5-year follow-up. The proportion of patients who achieved normal low-density lipoprotein cholesterol levels at 5 years post-LRYGB was greater than after LSG (30/49 [61.2%] versus 6/23 [26.1%]; P = .005), being male sex, absence of statins treatment, and type of BS technique (LRYGB) the associated factors with remission. Hypertriglyceridemia remission was also higher after LRYGB (23/25 [92.0%] versus 10/15 [66.7%]; P = .041), although type of surgery was not an associated factor. No differences were found in remission rates of low high-density lipoprotein cholesterol between groups. Absence of fibrates treatment and 5-year percentage of excess weight loss were independently associated with hypertriglyceridemia remission, and only the latter was independently associated with low high-density lipoprotein cholesterol remission 5 years after surgery. CONCLUSIONS: Five-year outcome data showed that, among patients with severe obesity undergoing BS, LRYGB was associated with a higher total and low-density lipoprotein cholesterol reduction and remission in comparison to LSG, with no differences in hypertriglyceridemia and high-density lipoprotein cholesterol normalization. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_17f9112fd8ff1da7cac01d0b53aa9166 |
| institution | Universitat Pompeu Fabra |
| instname_str | Universitat Pompeu Fabra |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:repositori.upf.edu:10230/42035 |
| publishDate | 2018 |
| publishDateSort | 2018 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| reponame_str | Repositorio Digital de la UPF |
| spelling | Changes in the lipid profile 5 years after bariatric surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy Climent, Elisenda Benaiges Foix, David Flores Le Roux, Juana Antonia Ramón Moros, José Manuel Pedro-Botet, Juan Goday Arnó, Albert Associated factors Dyslipidemia Laparoscopic Roux-en-Y gastric bypass Laparoscopic sleeve gastrectomy Bariatric surgery BACKGROUND: Few studies have compared mid-term results of laparoscopic Roux-en-Y gastric bypass (LRYGB) versus laparoscopic sleeve gastrectomy (LSG), and none have focused on lipid profile. OBJECTIVES: To compare LRYGB versus LSG with respect to lipid disturbance evolution and remission at mid-term after bariatric surgery (BS) and to assess associated factors with the remission of lipid disturbances at 5 years. SETTING: Hospital del Mar, Barcelona, from January 2005 to January 2012. METHODS: A retrospective analysis of a nonrandomized, prospective cohort was conducted on patients undergoing BS at Hospital del Mar, Barcelona, from January 2005 to January 2012 with ≥5 years' follow-up. RESULTS: Of 259 patients, 151 (58.3%) completed the 5-year follow-up. The proportion of patients who achieved normal low-density lipoprotein cholesterol levels at 5 years post-LRYGB was greater than after LSG (30/49 [61.2%] versus 6/23 [26.1%]; P = .005), being male sex, absence of statins treatment, and type of BS technique (LRYGB) the associated factors with remission. Hypertriglyceridemia remission was also higher after LRYGB (23/25 [92.0%] versus 10/15 [66.7%]; P = .041), although type of surgery was not an associated factor. No differences were found in remission rates of low high-density lipoprotein cholesterol between groups. Absence of fibrates treatment and 5-year percentage of excess weight loss were independently associated with hypertriglyceridemia remission, and only the latter was independently associated with low high-density lipoprotein cholesterol remission 5 years after surgery. CONCLUSIONS: Five-year outcome data showed that, among patients with severe obesity undergoing BS, LRYGB was associated with a higher total and low-density lipoprotein cholesterol reduction and remission in comparison to LSG, with no differences in hypertriglyceridemia and high-density lipoprotein cholesterol normalization. Elsevier http://hdl.handle.net/10230/42035 http://dx.doi.org/10.1016/j.soard.2018.05.006 |
| spellingShingle | Changes in the lipid profile 5 years after bariatric surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy Climent, Elisenda Associated factors Dyslipidemia Laparoscopic Roux-en-Y gastric bypass Laparoscopic sleeve gastrectomy Bariatric surgery |
| status_str | acceptedVersion |
| title | Changes in the lipid profile 5 years after bariatric surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy |
| title_full | Changes in the lipid profile 5 years after bariatric surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy |
| title_fullStr | Changes in the lipid profile 5 years after bariatric surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy |
| title_full_unstemmed | Changes in the lipid profile 5 years after bariatric surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy |
| title_short | Changes in the lipid profile 5 years after bariatric surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy |
| title_sort | Changes in the lipid profile 5 years after bariatric surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy |
| topic | Associated factors Dyslipidemia Laparoscopic Roux-en-Y gastric bypass Laparoscopic sleeve gastrectomy Bariatric surgery |
| topic_facet | Associated factors Dyslipidemia Laparoscopic Roux-en-Y gastric bypass Laparoscopic sleeve gastrectomy Bariatric surgery |
| url | http://hdl.handle.net/10230/42035 http://dx.doi.org/10.1016/j.soard.2018.05.006 |