Systematic review of clinical practice guidelines for long-term breast cancer survivorship: assessment of quality and evidence-based recommendations
BACKGROUND: Breast cancer is the most common cancer among women, with improved survival rates due to advances in early diagnosis and therapies. However, long-term survivors (≥5 years post-treatment, disease-free) face persistent physical, psychological, and social challenges requiring tailored, evid...
| Authors: | ; ; ; ; |
|---|---|
| Format: | Article |
| Status: | Published version |
| Publication date: | 2025 |
| Country: | España |
| Institution: | Universidad Pública de Navarra |
| Repository: | Academica-e. Repositorio Institucional de la Universidad Pública de Navarra |
| OAI Identifier: | oai:academica-e.unavarra.es:2454/54333 |
| Online Access: | https://hdl.handle.net/2454/54333 |
| Access Level: | Open access |
| Keyword: | Breast cancer survivorship Clinical Practice Guidelines (CPGs) Long-term outcomes Psychosocial care Evidence-based recommendations Survivorship care framework |
| _version_ | 1878729981573464064 |
|---|---|
| author | Pimentel Parra, Gustavo Adolfo |
| author2 | García Vivar, Cristina Escalada Hernández, Paula Santos Martín, José Luis Soto Ruiz, María Nelia |
| author2_role | author author author author |
| author_browse | Escalada Hernández, Paula García Vivar, Cristina Pimentel Parra, Gustavo Adolfo Santos Martín, José Luis Soto Ruiz, María Nelia |
| author_facet | Pimentel Parra, Gustavo Adolfo García Vivar, Cristina Escalada Hernández, Paula Santos Martín, José Luis Soto Ruiz, María Nelia |
| author_role | author |
| collection | Academica-e. Repositorio Institucional de la Universidad Pública de Navarra |
| description | BACKGROUND: Breast cancer is the most common cancer among women, with improved survival rates due to advances in early diagnosis and therapies. However, long-term survivors (≥5 years post-treatment, disease-free) face persistent physical, psychological, and social challenges requiring tailored, evidence-based care. Despite the growing survivor population, no systematic evaluation of Clinical Practice Guidelines (CPGs) for this group has been conducted. This study assesses the quality of CPGs and their evidence-based recommendations. METHODS: A systematic review was conducted in PubMed, CINAHL, and Cochrane Library (2015–2023), including guidelines from major oncology organisations. The AGREE II instrument evaluated CPG quality across six domains, and recommendations were classified using a Primary Care survivorship framework: prevention, surveillance, care coordination, and long-term effect management. RESULTS: Ten CPGs met inclusion criteria, with 7 classified as high quality. Most recommendations focused on prevention (adjuvant therapy, alcohol) and surveillance (follow-up, mammography), while gaps remained in lifestyle guidance, psychosocial support, and management of complications (lymphedema, osteoporosis, cognitive dysfunction). Care coordination and psychosocial interventions were inconsistently addressed. CONCLUSIONS: Current CPGs inadequately cover the complex needs of long-term survivors, particularly in psychosocial care. Evidence-based, patient-centred guidelines are urgently needed to optimise long-term outcomes and quality of life. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_12fb5259ebee548b7e12edd3fc4d2b2e |
| institution | Universidad Pública de Navarra |
| instname_str | Universidad Pública de Navarra |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:academica-e.unavarra.es:2454/54333 |
| publishDate | 2025 |
| publishDateSort | 2025 |
| publisher | Springer Nature |
| publisherStr | Springer Nature |
| reponame_str | Academica-e. Repositorio Institucional de la Universidad Pública de Navarra |
| spelling | Systematic review of clinical practice guidelines for long-term breast cancer survivorship: assessment of quality and evidence-based recommendations Pimentel Parra, Gustavo Adolfo García Vivar, Cristina Escalada Hernández, Paula Santos Martín, José Luis Soto Ruiz, María Nelia Breast cancer survivorship Clinical Practice Guidelines (CPGs) Long-term outcomes Psychosocial care Evidence-based recommendations Survivorship care framework BACKGROUND: Breast cancer is the most common cancer among women, with improved survival rates due to advances in early diagnosis and therapies. However, long-term survivors (≥5 years post-treatment, disease-free) face persistent physical, psychological, and social challenges requiring tailored, evidence-based care. Despite the growing survivor population, no systematic evaluation of Clinical Practice Guidelines (CPGs) for this group has been conducted. This study assesses the quality of CPGs and their evidence-based recommendations. METHODS: A systematic review was conducted in PubMed, CINAHL, and Cochrane Library (2015–2023), including guidelines from major oncology organisations. The AGREE II instrument evaluated CPG quality across six domains, and recommendations were classified using a Primary Care survivorship framework: prevention, surveillance, care coordination, and long-term effect management. RESULTS: Ten CPGs met inclusion criteria, with 7 classified as high quality. Most recommendations focused on prevention (adjuvant therapy, alcohol) and surveillance (follow-up, mammography), while gaps remained in lifestyle guidance, psychosocial support, and management of complications (lymphedema, osteoporosis, cognitive dysfunction). Care coordination and psychosocial interventions were inconsistently addressed. CONCLUSIONS: Current CPGs inadequately cover the complex needs of long-term survivors, particularly in psychosocial care. Evidence-based, patient-centred guidelines are urgently needed to optimise long-term outcomes and quality of life. This research was funded by the National Institute of Health Carlos III (ISCIII), Spain, grant number PI21/00894. Springer Nature https://hdl.handle.net/2454/54333 |
| spellingShingle | Systematic review of clinical practice guidelines for long-term breast cancer survivorship: assessment of quality and evidence-based recommendations Pimentel Parra, Gustavo Adolfo Breast cancer survivorship Clinical Practice Guidelines (CPGs) Long-term outcomes Psychosocial care Evidence-based recommendations Survivorship care framework |
| status_str | publishedVersion |
| title | Systematic review of clinical practice guidelines for long-term breast cancer survivorship: assessment of quality and evidence-based recommendations |
| title_full | Systematic review of clinical practice guidelines for long-term breast cancer survivorship: assessment of quality and evidence-based recommendations |
| title_fullStr | Systematic review of clinical practice guidelines for long-term breast cancer survivorship: assessment of quality and evidence-based recommendations |
| title_full_unstemmed | Systematic review of clinical practice guidelines for long-term breast cancer survivorship: assessment of quality and evidence-based recommendations |
| title_short | Systematic review of clinical practice guidelines for long-term breast cancer survivorship: assessment of quality and evidence-based recommendations |
| title_sort | Systematic review of clinical practice guidelines for long-term breast cancer survivorship: assessment of quality and evidence-based recommendations |
| topic | Breast cancer survivorship Clinical Practice Guidelines (CPGs) Long-term outcomes Psychosocial care Evidence-based recommendations Survivorship care framework |
| topic_facet | Breast cancer survivorship Clinical Practice Guidelines (CPGs) Long-term outcomes Psychosocial care Evidence-based recommendations Survivorship care framework |
| url | https://hdl.handle.net/2454/54333 |