Cancer, Epigenetics And The Nobel Prizes

The Nobel Prize in Physiology or Medicine 2012 have been awarded jointly to Sir John B. Gurdon and Shinya Yamanaka “for the discovery that mature cells can be reprogrammed to become pluripotent” as it is described in the Nobel Prize web site. Professors Gurdon and Yamanaka have all the merits to be...

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Bibliographic Details
Author: Esteller, Manel
Format: Article
Status:Published version
Publication date:2012
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/123975
Online Access:https://hdl.handle.net/2445/123975
Access Level:Open access
Keyword:Premis Nobel
Càncer
Epigenètica
Nobel Prizes
Cancer
Epigenetics
Description
Summary:The Nobel Prize in Physiology or Medicine 2012 have been awarded jointly to Sir John B. Gurdon and Shinya Yamanaka “for the discovery that mature cells can be reprogrammed to become pluripotent” as it is described in the Nobel Prize web site. Professors Gurdon and Yamanaka have all the merits to be bestowed with such a prestigious award for their seminal discoveries in the area. However, we can also consider this annual prize as a recognition to Epigenetics, similarly to the Nobel Prize of 2006 for Andrew Z. Fire and Craig C. Mello for their of RNA interference - gene silencing by doublestranded RNA. Reprogramming requires changing the epigenome of the cells and non-coding RNAs are critical elements in the establishment of epigenetic patterns