Antioxidant and antimicrobial assessment of licorice supercritical extracts
Licorice (Glycyrrhiza glabra L.) is a plant used widely in herbal medicines due to their several biological potentials. The supercritical extraction of licorice roots was investigated to assess the antioxidant and antimicrobial activity of the extracts. Extraction conditions were pressures from 15 t...
| Authors: | ; ; ; ; ; |
|---|---|
| Format: | Article |
| Publication date: | 2019 |
| Country: | España |
| Institution: | Universidad Autónoma de Madrid |
| Repository: | Biblos-e Archivo. Repositorio Institucional de la UAM |
| Language: | English |
| OAI Identifier: | oai:repositorio.uam.es:10486/695772 |
| Online Access: | http://hdl.handle.net/10486/695772 https://dx.doi.org/10.1016/j.indcrop.2019.111496 |
| Access Level: | Open access |
| Keyword: | Antibacterial Antioxidant Bioactive compounds Glycyrrhiza glabraa Licorice Supercritical carbon dioxide Química |
| _version_ | 1878729535398084609 |
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| author | Quintana, Somaris E. |
| author2 | Cueva, Carolina Villanueva-Bermejo, David Moreno-Arribas, M. Victoria Fornari Reale, Tiziana Rodríguez García-Risco, Mónica |
| author2_role | author author author author author |
| author_browse | Cueva, Carolina Fornari Reale, Tiziana Moreno-Arribas, M. Victoria Quintana, Somaris E. Rodríguez García-Risco, Mónica Villanueva-Bermejo, David |
| author_facet | Quintana, Somaris E. Cueva, Carolina Villanueva-Bermejo, David Moreno-Arribas, M. Victoria Fornari Reale, Tiziana Rodríguez García-Risco, Mónica |
| author_role | author |
| collection | Biblos-e Archivo. Repositorio Institucional de la UAM |
| description | Licorice (Glycyrrhiza glabra L.) is a plant used widely in herbal medicines due to their several biological potentials. The supercritical extraction of licorice roots was investigated to assess the antioxidant and antimicrobial activity of the extracts. Extraction conditions were pressures from 15 to 40 MPa, 313.15 and 333.15 K, and ethanol cosolvent in the range of 0 to 20% mass. In the case of high-pressure extractions using pure carbon dioxide (CO2) fractionation of the supercritical extract was accomplished in a two-cell decompression system. Fractionation was carried out with the aim to examine the potential separation of the antioxidant and antimicrobial licorice compounds and thus increase the bioactive properties of the fractions obtained in each separation cell. Main licorice bioactive compounds, liquiritin, liquiritigenin, glycyrrhizin, isoliquiritigenin and glabridin, were identified by HPLC and quantified using standards. Extracts obtained with supercritical CO2 and ethanol cosolvent contain the higher amounts of phenolic compounds and also the higher antioxidant activity but exhibit low or even no antimicrobial activity. Using pure CO2 at high pressure coupled with the on-line fractionation of the extract, two samples were obtained which showed, respectively, lower phenolic compounds content and good antimicrobial capacity (first fraction) and higher phenolic compounds content and antioxidant capacity (second fraction). Thus, the advantages of supercritical on-line fractionation are demonstrated in the extraction of Licorice roots |
| eu_rights_str_mv | openAccess |
| format | article |
| id | ES_09e3800a10264eaa089a21cdaa8229ea |
| institution | Universidad Autónoma de Madrid |
| instname_str | Universidad Autónoma de Madrid |
| language | eng |
| network_acronym_str | ES |
| network_name_str | España |
| oai_identifier_str | oai:repositorio.uam.es:10486/695772 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| reponame_str | Biblos-e Archivo. Repositorio Institucional de la UAM |
| spelling | Antioxidant and antimicrobial assessment of licorice supercritical extracts Quintana, Somaris E. Cueva, Carolina Villanueva-Bermejo, David Moreno-Arribas, M. Victoria Fornari Reale, Tiziana Rodríguez García-Risco, Mónica Antibacterial Antioxidant Bioactive compounds Glycyrrhiza glabraa Licorice Supercritical carbon dioxide Química Licorice (Glycyrrhiza glabra L.) is a plant used widely in herbal medicines due to their several biological potentials. The supercritical extraction of licorice roots was investigated to assess the antioxidant and antimicrobial activity of the extracts. Extraction conditions were pressures from 15 to 40 MPa, 313.15 and 333.15 K, and ethanol cosolvent in the range of 0 to 20% mass. In the case of high-pressure extractions using pure carbon dioxide (CO2) fractionation of the supercritical extract was accomplished in a two-cell decompression system. Fractionation was carried out with the aim to examine the potential separation of the antioxidant and antimicrobial licorice compounds and thus increase the bioactive properties of the fractions obtained in each separation cell. Main licorice bioactive compounds, liquiritin, liquiritigenin, glycyrrhizin, isoliquiritigenin and glabridin, were identified by HPLC and quantified using standards. Extracts obtained with supercritical CO2 and ethanol cosolvent contain the higher amounts of phenolic compounds and also the higher antioxidant activity but exhibit low or even no antimicrobial activity. Using pure CO2 at high pressure coupled with the on-line fractionation of the extract, two samples were obtained which showed, respectively, lower phenolic compounds content and good antimicrobial capacity (first fraction) and higher phenolic compounds content and antioxidant capacity (second fraction). Thus, the advantages of supercritical on-line fractionation are demonstrated in the extraction of Licorice roots The authors gratefully acknowledge the financial support from Ministerio de Economía y Competitividad of Spain (Projects AGL2016-76736-C3-1-R and AGL2015-64522-C2-R) Elsevier http://hdl.handle.net/10486/695772 https://dx.doi.org/10.1016/j.indcrop.2019.111496 |
| spellingShingle | Antioxidant and antimicrobial assessment of licorice supercritical extracts Quintana, Somaris E. Antibacterial Antioxidant Bioactive compounds Glycyrrhiza glabraa Licorice Supercritical carbon dioxide Química |
| title | Antioxidant and antimicrobial assessment of licorice supercritical extracts |
| title_full | Antioxidant and antimicrobial assessment of licorice supercritical extracts |
| title_fullStr | Antioxidant and antimicrobial assessment of licorice supercritical extracts |
| title_full_unstemmed | Antioxidant and antimicrobial assessment of licorice supercritical extracts |
| title_short | Antioxidant and antimicrobial assessment of licorice supercritical extracts |
| title_sort | Antioxidant and antimicrobial assessment of licorice supercritical extracts |
| topic | Antibacterial Antioxidant Bioactive compounds Glycyrrhiza glabraa Licorice Supercritical carbon dioxide Química |
| topic_facet | Antibacterial Antioxidant Bioactive compounds Glycyrrhiza glabraa Licorice Supercritical carbon dioxide Química |
| url | http://hdl.handle.net/10486/695772 https://dx.doi.org/10.1016/j.indcrop.2019.111496 |